Mike Martynowycz

Opinions are my own.

[Mike Martynowycz @ScienceMick]

Our work on ab initio phasing #MicroED data is now published @naturemethods! Big thanks to @markherzik @_KevinCorbett for writing an awesome News & Views (and Mark for reviewing the work). Big thanks to @gonenlab @maxclabbers and Johan for their hard work! https://t.co/tHJuen5rPR

[Mike Martynowycz @ScienceMick]

Dog is 9

[Mike Martynowycz @ScienceMick]

@CorneliusGati @PaulLXavier @Penn @PennMedicine Congratulations!

[Mike Martynowycz @ScienceMick]

👀
The Frontiers of Structure | Science | AAAS https://t.co/3J9NZaAtTy

[Tomasz Góral @t_goral]

Another fantastic results published in #JACS. This work shows a great potential of #microED for studying mineralogical and geological samples. ED data were acquired on our Glacios at CeNT UW. https://t.co/riabujXUkB

[Mike Martynowycz @ScienceMick]

🍃➡️🧬 First paper from the Martynowycz Lab!
Spontaneous seed-protein nanocrystals → 0.85Å ab-initio structure of crambin by #MicroED No crystallization screens, no MR bias.

Watch the diffraction-to-density movie & grab the preprint below!

https://t.co/6FJWU5gg4S

[Mike Martynowycz @ScienceMick]

Dog is 8

[Mike Martynowycz @ScienceMick]

Coming soon! Deep dish Eucharist. #Chicago #Pope

[Barack Obama @BarackObama]

Congratulations to Judge Susan Crawford on her victory, and to the people of Wisconsin for electing a judge who believes in the rule of law and protecting our freedoms.

[UBuffalo Hauptman-Woodward Research Institute @UB_HWI]

What holds your eye lens together? UCLA scientists along with now UB-HWI faculty found out! Using advanced microcrystal electron diffraction, they solved the structure of the abundant lens protein MP20. https://t.co/0DITZpNSdd

[Tamir Gonen @gonenlab]

Super stoked that this study is finally out

Heroic effort from several people and of course #cryoem #MicroED #FIB 👍👍

Structure of the lens MP20 mediated adhesive junction | Nature Communications

https://t.co/l17MWmHr9B

[UBuffalo Hauptman-Woodward Research Institute @UB_HWI]

Researchers from UCLA and UB-HWI have pushed the boundaries of electron crystallography, achieving sub-atomic resolution using energy-filtered #MicroED #CryoEM. This improves structural detail, advancing drug discovery and biomolecular research. https://t.co/4ZdgiIhqai

[Mike Martynowycz @ScienceMick]

@IsraelF96135088 Yes

[Tamir Gonen @gonenlab]

Now most folks cant tell the difference between an Xray diffraction pattern and #MicroED 😁

Behold 0.9Å 😍

[Mike Martynowycz @ScienceMick]

Our latest work shows how energy filtering, PFIB, and direct electron detection unlock sub-atomic resolution for #MicroED! 🎯

Great work from @maxclabbers and JohanHattne back when I was with @gonenlab at @BC_UCLA. Excited to bring this capability to @UBuffalo!

[Tamir Gonen @gonenlab]

Happy to share high throughput ligand and inhibitor screening against enzymes using MicroED. Drug discovery based on structures

Ligand Screening and Discovery using Cocktail Soaking and Automated MicroED | bioRxiv https://t.co/4cWhylMBvg

[Sven Klumpe @svenklumpe]

Happy to share our manuscript on the in situ visualization of the copia retrotransposon in its final form today published in @CellCellPress https://t.co/bTSd8t4POV . What’s new?

[Tamir Gonen @gonenlab]

Probing ion channel dynamics at atomic resolution using vanishingly small crystals and #MicroED.

Yes, dynamics can be probed even qith crystals...

High-throughput MicroED for probing ion channel dynamics | bioRxiv https://t.co/SGgkghbmlE

[Tamir Gonen @gonenlab]

Whats the best slit width for your energy filter? ⁦@maxclabbers⁩ systematically tested the settings. The results may surprise you...

Characterization of energy filtering slit widths for MicroED data collection | bioRxiv https://t.co/P7I3jischP

[Tamir Gonen @gonenlab]

The 7th Challenges in Structural Biology Summit will be 9/9-12/25 at UCLAs Lake Arrowhead Resort. @BrentNannenga and I are taking nominations for speakers. Please write, self nominations are OK. Focus is on methods and challenges. Everyone speaks. Limited to 50 speakers/attendees

[Mike Martynowycz @ScienceMick]

@gonenlab @HWMRI @UBuffalo Capitals cost extra 😂

[Mike Martynowycz @ScienceMick]

I’m happy to share that @HWMRI has merged with @UBuffalo. My lab will stay at HWI, and my title is changing. I’m starting a new position as a tenure track Assistant Professor at the Jacob’s School of Medicine at the University at Buffalo!