Leonardo Velazco-Cruz

Pluripotent stem cell scientist developing next-gen β islet therapies.

[Juan [email protected] @JuanAlvarezDom]

🚨Preprint alert #1🚨AI-driven spatial transcriptomics for a SC-pancreas transplant test case - fantastic collaboration with @ganoopyliujia @wenbowang11 @ZuwanLin - checkout the youtube demo!

[Jeffrey Millman @JeffreyRMillman]

Sana Biotechnology's first-in-human study of hypoimmune-engineered deceased donor islets shows insulin production & immune evasion without immunosuppression #Diabetes #T1D #CellTherapy https://t.co/ynsDJKmP0o

[Heiko Lickert @LickertHeiko]

Thrilled to share one of our biggest discoveries: “Inceptor binds to and directs insulin towards lysosomal degradation in beta cells”.
https://t.co/GKx6eslJz0
A tremendous collaborative effort led by @JohannaSiehler, @BilekovaSara and other members of the @LickertHeiko lab.

[XX @bcellorg]

Online @Cell_Metabolism - a Focus on https://t.co/aAsQpIBqEu. Views on data accessibility, sharing, quality, and general thoughts on the field.

“https://t.co/SzapxteAFl: Improving accessibility, integration, and usability of human research islet data”

https://t.co/y9lrQob5M4

[Prof Lennart Nacke, PhD @acagamic]

The classic hourglass structure of paper writing
#academicx #phdchat

[Jeffrey Millman @JeffreyRMillman]

🧬 Exciting new study out in @NatureComms! We identify cell-type-specific responses in pancreatic islets to stress, shedding light on diabetes progression. It is #OpenAccess for all to download for free! #DiabetesResearch @WUSTLmed @WUDeptMedicine https://t.co/7s0534QwYu

[Jeffrey Millman @JeffreyRMillman]

Hey, that's me! :)

[Diego Balboa @_DiegoBalboa_]

Thrilled to announce we just got funded by @novonordiskfond Research Leader program!! We will explore the mechanisms behind islet cell maturation using human pluripotent stem cells. Recruiting PostDocs and PhD students really soon, get in touch ;) @STEMMProgram @helsinkiuni

[Jeffrey Millman @JeffreyRMillman]

Congrats to Millman lab alumni @ericamarquez95 and her @American_Heart fellowship!

[Eric Topol @EricTopol]

Our most complex biologic system—immunity—is reviewed in 3 new @CellCellPress papers, open-access
Adaptive
https://t.co/rJRBnV7u8I
Innate
https://t.co/PMKA6KgL7R
New insights
https://t.co/rJRBnV7u8I @RMedzhitov

[WashU Medicine Endocrinology @WashUMedEndo]

Endocrine-metabolic research at #WashUMed can be traced to the Nobel Prize-winning work of Drs. Carl and Gerty Cori. Among their trainees were Drs. William H. Daughaday and David M. Kipnis, who molded and led our division during the 1950s-1970s.
Read more: https://t.co/7ehUYrsnFR

[Jeffrey Millman @JeffreyRMillman]

We previously performed a study demonstrating AMX0035 improves in Wolfram Syndrome patient iPSC-derived islets with @FumihikoUrano. @amylyxpharma just announced interim clinical trial data with AMX0035 showing improved diabetes and vision! Congratulations! https://t.co/FweSU8FlRa

[Christos Karampelias @CKarampelias]

Great work from the lab and a thorough characterization of pig pancreas development and comparison to other species! Congrats to @Carina_K_YANG @HannahSpitzer1 and all authors for the highly collaborative project! See tweetorial from the boss below for more details on the work!

[Daniel J Drucker @DanielJDrucker]

Here comes once weekly insulin #diabetes

[Pancreatic Cell News @PancreaticCell]

🗺️ Scientists charted a high-resolution roadmap with scRNA-seq to investigate pathogenesis of wolfram syndrome #βcell failure, revealing two distinct cellular fates along pseudotime trajectory: maturation and stress branches.

#OpenAccess in @cddpress:
🔗 https://t.co/hfkQUgRmdP

[Daniel J Drucker @DanielJDrucker]

New from @HuisingLab @ucdavis The physiological role of δ cells and SST is to provide tonic feedback inhibition that reduces the β cell glucose threshold and consequently lowers the glycaemic set point in vivo #islets #diabetes @NatMetabolism https://t.co/bfnunRbmwV

[Joseph Ross @rossbiology]

A thing I ❤️ about my job is I'm lab-active. Semester is done; winter project going! 60 F1 hybrids; 500 plates poured for some F2s…time for some genetics! This will be a multi-day 🧵, which might become cautionary, about chasing an interesting observation w/dubious impact 1/n

[XX @bcellorg]

Bright and sensitive red voltage indicators for imaging action potentials in brain slices and pancreatic islets | Science Advances https://t.co/J4VELofWUZ

[Pancreatic Cell News @PancreaticCell]

Drs. Z. Ian Hu at @MDAndersonNews and Eileen O’Reilly at @MSKCancerCenter highlight contemporary areas of research for pancreatic cancer, including poly(ADP-ribose) polymerase inhibitors, KRAS-targeted therapies, and #immunotherapies.

https://t.co/OT1Xx9YtvG

[Islet Biology Lab - UMH @isletbiologylab]

Dr. Leete provides an overview of pancreatic anatomy, and the importance of research focused on the pancreas in #type1diabetes, which ranges from histological breakthroughs to briefly discussing the challenges associated with characterizing the organ.
https://t.co/4MDVwnuFZm