Steve Garguilo

Founder, @wearecultivate. Empowering changemakers inside big companies. Card-carrying member of both @sheetz and @wawa.

[Prompter @PromptLLM]

you need to start visualising

[Steve Garguilo @sdgarguilo]

Hotel lobby productivity is one of my favorite forms of productivity.

[Derek Thompson @DKThomp]

This has quietly been a miracle month in medicine.

In the last 5 weeks we’ve got news on:

- retatrutide, the triple agonist GLP-1 from Lilly, basically melting fat and body-wide inflammation at record levels
- RevMed’s new pancreatic cancer drug showing unprecedented abilities to extend life
- small trial of a one-and-done PCSK9 gene editing therapy for slashing LDL cholesterol
- Mayo’s AI-assisted radiology showing vastly improved cancer detection
- this new therapy for metastatic solid tumors

This stuff is at varying levels of evidence. Retatrutide is ~100% on its way, other stuff needs more clinical trial data. But put it together and we’re maybe on the verge of majorly reducing the mortality of heart disease and cancer, the two leading causes of death in America.

[Rajvi @rajvishah30]

today someone in office said that “worrying is the worst way to use your imagination” and that’s easily the best thing Ive heard all week

[Nicholas Fabiano, MD @NTFabiano]

Worrying about the future is associated with poor mental health.

Be in the present.

[Smirkley @Smirkley]

A 5-gallon water cooler jug of water produces about $132 in economic output from data centers, but only about 2 cents from almonds.

[Steve Garguilo @sdgarguilo]

@BiancoDavinci Still very much there! And they have one of the “new” Pizza Huts!

[Matt Braynard @MattBraynard]

We're so back.

An entrepreneur is restoring Pizza Huts to their former glory.

[Jason Saltzman @saltzman_jason]

The businesses getting the most out of AI right now aren't tech companies.

They’re plumbers, agency owners, dentists, Etsy sellers.

New data from @OpenAI (cc @RonnieChatterji) makes the pattern clear: tech startups account for about 5% of ~active~ U.S. users doing entrepreneurial work with ChatGPT.

The other 95% are spread across services, retail, healthcare, and trades.

AI adoption for entrepreneurship isn’t concentrated in tech. It’s happening inside everyday businesses, folding into routine work that used to be slower or outsourced or entirely overlooked.

[Tim Tebow @TimTebow]

Attitude is a choice.
Gratitude is a discipline.
Bitterness is expensive.

Nobody accidentally has a great attitude.
Nobody stumbles into gratitude.
And nobody means to end up bitter, it just quietly moves in when you stop choosing something better.
Guard your peace like it cost you something.
Because it did.

[Justin Skycak @justinskycak]

"Your lack of urgency is wasting your potential."

[Alec Stapp @AlecStapp]

One of my favorite stats that serves as a reality check for people:

The median American took zero flights last year.

[Jaya Gupta @JayaGup10]

https://t.co/5vDrndcmFn

[Siddharth Khurana @SidKhurana3607]

Counties with a median income above 100K:

[Steve Garguilo @sdgarguilo]

@businessbarista AI-native

[Christina Agapakis @thisischristina]

Husband and Claude set up a receipt printer to make daily briefings for the kids

[Steve Garguilo @sdgarguilo]

Just ran into @JonHaidt and was glad I could thank him personally for his work helping to save kids from the harmful effects of too much phone time.

[James Clear @JamesClear]

Life rarely changes in a positive way without an increase in responsibility.

That can mean taking ownership of your health or committing to a relationship or starting a business.

Whatever it is, if you want the trajectory to change, the amount of responsibility usually has to change.

[Vala Afshar @ValaAfshar]

Complaining is not a strategy.