SigniosBio

AI-powered multiomics & bioinformatics. An affiliate of MedGenome. Global RWE to support discovery in oncology, rare disease & more.

[SigniosBio @SigniosBio]

Welcome to Signios Bio, where we are decoding the future of healthcare with multiomics and AI-powered bioinformatics. https://t.co/5aEmvtrYSF
#SigniosBio #Multiomics #ScienceOfSignals

[SigniosBio @SigniosBio]

We’re heading to #ASH2025 in Orlando. Visit Signios Bio at Booth 165, Dec 6–9.

Learn how we support hematology research with single-cell RNA seq, spatial transcriptomics, bulk sequencing and TCR/BCR profiling. Schedule a time to connect
https://t.co/eYPTDOIzGY

[SigniosBio @SigniosBio]

Checkpoint response reflects clonal expansion, transcriptional state, and spatial context in the TME. Signios provides immune profiling from bulk TCR/BCR sequencing to single-cell V(D)J analysis for immuno-oncology research. https://t.co/zPKCSv7hzz
#ImmunoOncology #TCRSeq #BCRSeq

[SigniosBio @SigniosBio]

Antibody repertoires reveal how B cells shape the immune response in cancer.

Our RNA-based BCR workflows capture full-length chains and quantify diversity, even from FFPE samples.

Read the white paper: https://t.co/0fNCIAeG4r

#BCRSequencing #RNAseq #ImmunoOncology

[SigniosBio @SigniosBio]

Visium HD or Xenium Prime 5K? Two paths to spatial insights—one for broad, unbiased discovery, the other for targeted, cell-level precision. Read how each fits discovery and validation workflows: https://t.co/aF9ti97Mxa
#SpatialBiology #SingleCell #SpatialTranscriptomics

[ArgenTag @argentagbio]

The Future is Single-Cell Long-Read @GeneticsSociety

Thanks to all the innovators we had exciting discussions with about how to advance the Single-Cell Long-Read space. STAY TUNED! @PacBio, @nanopore, @Roche, @Singleron_Bio, @TwistBioscience, @ParseBio, @BioRad, @RNA_Connect, @SigniosBio, @GenomeWeb

[SigniosBio @SigniosBio]

Last chance: Live webinar tomorrow, 10:00 am PT. Single-cell with tumor genomics and transcriptomics in multiple myeloma. Register: https://t.co/t8qKpPfDNO Can’t make it? Register anyway, get the recording. #MultipleMyeloma #SingleCell

[SigniosBio @SigniosBio]

Signios is at #ASHG2025! Find us at Booth 2603, end of Row 2500. Ask about our free RNA-seq offer, long-read sequencing with @PacBio, and single-cell, spatial with @10xGenomics and proteomics solutions @OlinkProteomics. https://t.co/22acMoNDQD

[SigniosBio @SigniosBio]

Live webinar with Dr. David Coffey (U Miami): integrating tumor genomics , transcriptomics and immune single-cell profiling in multiple myeloma. Oct 21, 10:00 am PT. Register: https://t.co/Lg5UhtTdeV
#MultipleMyeloma #SingleCell #CancerResearch #ImmunoOncology #Genomics

[SigniosBio @SigniosBio]

As #AlzheimersBrainAwarenessMonth ends, see how single-cell, spatial & long-read sequencing are used to study brain complexity in TBI, FTD, FA & Alzheimer’s.
Read more: https://t.co/KU0ycjpyz7
#NeuroscienceResearch #Genomics

[SigniosBio @SigniosBio]

#BrainAwarenessMonth: Prof. Theus (Virginia Tech) on #TBI research with Signios Bio: “…we validated signaling at the protein level and tested it therapeutically in our model.” Multiomics made it possible. Read the TBI story: https://t.co/Fds5oYAySs #Multiomics #ScienceOfSignals

[SigniosBio @SigniosBio]

It’s still #BrainAwarenessMonth. Signios Bio supported scRNA-seq in a progranulin deficiency study, uncovering diverse microglia-like cells: https://t.co/l84xC1qsTk
Explore our single-cell services: https://t.co/CoZMfb4Er2
#scRNAseq #Genomics

[SigniosBio @SigniosBio]

For #BrainAwarenessMonth: Stanford study (w/ scRNA-seq + bioinformatics by Signios Bio) reveals 6 microglia-like cell subtypes in a model of progranulin deficiency (#FTD). New insights into CNS cell replacement. Preprint: https://t.co/kBwMPhWNJD
#scRNAseq #ScienceOfSignals

[SigniosBio @SigniosBio]

It’s Alzheimer’s & Brain Awareness Month. Signios Bio supports brain research with Neuroregulation Signal (to identify vulnerable neurons) and Neuroimmune Signal (to map immune activity). Learn more: https://t.co/2SlMo1KbYy
#BrainAwarenessMonth #Neuroscience #ScienceOfSignals

[SigniosBio @SigniosBio]

New grant alert! Illumina & Signios Bio are offering no-cost proteomic analysis (up to 170 samples, 9.5K proteins via NovaSeq) + expert support + a chance to present your work. Apply by June 27!
Press release: https://t.co/oPcsJ5pEHw
Apply: https://t.co/dwJNZ4S11f

[SigniosBio @SigniosBio]

Advancing #ImmunoOncology research? Check out our latest application note on how single-cell profiling revealed immunologic signatures of response and resistance to ICIs in metastatic cancer. https://t.co/v9BQ1oxmY7 #SigniosBio #ImmunoOncology #SingleCell #ScienceOfSignals

[SigniosBio @SigniosBio]

See beyond the genome with HiFi sequencing to directly map DNA methylation (5mC, no bisulfite!) & resolve complex SVs missed by short reads. Explore cancer epigenetics & genomics with #SigniosBio https://t.co/szzKaeOfgR #Hi

[PacBio @PacBio]

More data, less DNA. With #SPRQ chemistry, Signios Biosciences is unlocking #HiFisequencing for tough samples—boosting output and expanding access to more sample types.

🔗 See how they’re using SPRQ to scale impact and access: https://t.co/OFBQ6dwOF2

#PacBio #PacBioSPRQ

[SigniosBio @SigniosBio]

Short-read RNA-seq missing key cancer transcript details? #SigniosBio's long-read RNAseq provides full-length clarity on isoforms, fusions & splice variants. Get in touch to learn more. https://t.co/UgBr5EOjz0 #IsoSeq #HiFiSequencing #RNA #CancerResearch #ScienceOfSignals

[SigniosBio @SigniosBio]

Researching #HematologicMalignancies? Check out our new application note to see solutions and how they helped researchers uncover microenvironment changes after GSI treatment in multiple myeloma https://t.co/OPH8qVx0u4 #SigniosBio #Hematology #Multiomics #ScienceOfSignals

[SigniosBio @SigniosBio]

Dissecting LUSC heterogeneity with scRNA-seq: See how researchers identified KLF4-driven hillock-like states in our new solid tumor profiling note. https://t.co/7PeEP2Ikw7. #CancerResearch #Genomics #SingleCell #SigniosBio #ScienceOfSignals