Sin_Reni

Account ufficiale della Società Italiana di Nefrologia (SIN) - Official account of the Italian Society of Nephrology - L’account @SinReni non è più online

[Sin_Reni @Sin_Reni]

Se sei socio attivo della #SIN, hai accesso libero alle riviste scientifiche e puoi anche richiedere articoli specifici per aggiornarti e migliorare la pratica clinica.
Scopri come 👉 https://t.co/8gHr4EmL0Q
#Nefrologia #RenePolicistico #MalattiaRenaleCronica #SaluteRenale

[Centro Nazionale Trapianti @CNTrapianti]

West Nile Virus: crescono i casi ma le donazioni restano sicure.

Negli ultimi tre anni i casi in Italia sono più che raddoppiati ma non si è verificata la trasmissione dopo trasfusione o trapianto di organi, tessuti e cellule. Qui il comunicato completo: https://t.co/soB30POCqj

[Fluid Academy @Fluid_Academy]

💧 Fluid Management in Sepsis and Septic Shock

Early, but Not Excessive

This core chapter revisits sepsis resuscitation in the era of stewardship, showing how initial fluids remain essential to reverse life‑threatening hypoperfusion, but fixed large bolus protocols can lead to harmful volume overload when applied indiscriminately. It integrates the ROSE concept, emphasizing short, targeted resuscitation followed by optimization and, where needed, timely evacuation.

Dynamic Assessment and Early Vasopressors

The authors advocate dynamic tests of fluid responsiveness (passive leg raising, stroke volume variation, echocardiographic indices) and early vasopressor support rather than repeated blind boluses. Evidence linking positive fluid balance with mortality in sepsis is summarized, underlining the need for explicit stop rules and deresuscitation plans once shock has resolved.

📘 Full sepsis algorithms and case vignettes in Chapter 14.
🔵 IFAD 2026 in Antwerp will devote multiple sessions to sepsis fluid management, including hands‑on hemodynamics and stewardship.
👉Registration: https://t.co/wATwBWAIge

#Sepsis #SepticShock #FluidResuscitation #ICU #ROSE #FluidStewardship

[ERA - European Renal Association @ERAkidney]

🩺 More than 500,000 people across the EU are receiving kidney replacement therapy (KRT) – a figure that has grown by around 150% since 1990.

The latest ERA Registry data highlights both the advances made in treating kidney failure and the challenges that remain.

Key findings include:
📌 Wide variation in KRT prevalence and treatment patterns across the EU
📌 Haemodialysis remains the predominant treatment pathway for patients starting KRT
📌 Survival outcomes differ markedly between treatment modalities, with transplantation associated with better long-term outcomes

As the number of people living with kidney failure continues to rise, strengthening early CKD detection, ensuring equitable access to KRT and reducing disparities in care across Europe will be critical to improving patient outcomes.

👉 https://t.co/3QI1mWl4wo

#ERARegistry #KidneyHealth #KRT #ERA #KidneyReplacementTherapy #KidneyTransplant #Dialysis #CKD

[Sin_Reni @Sin_Reni]

Fresh evidence on kidney stone prevention. A new Annals of Internal Medicine review highlights the role of higher fluid intake, reduced salt and animal protein, and targeted therapies Read the open‑access article: https://t.co/zLWkO6ZFYk #Nefrologia #CalcolosiRenale #SaluteRenale

[Sin_Reni @Sin_Reni]

Last year at the 66th #SIN2025 Congress, Dr. Luca De Nicola and Dr. Maura Ravera highlighted key updates on CKD screening and holistic care.
👇 Watch the talks 🇮🇹
👉 Screening law & Observatory: https://t.co/i62kteOkZD
👉 CKD burden & new therapies: https://t.co/Ck1UGa4csd

[AJKD @AJKDonline]

Advice for Living With Hemodialysis: A Qualitative Study of Older Patients and Their Care Partners

https://t.co/E7yoMJD2Ns (OPEN ACCESS)

@PhD_NDePasquale @Rasheeda_HallMD @barrett_bowling

[ERA - European Renal Association @ERAkidney]

1/6 🧵 #ERA26 - High impact clinical trials in Nephrology. #ChallengeYourThinking
🪑 Chairs: Mario Gennaro Cozzolino @MarioCozzolin19, Kaitlin Mayne

GOOD-IDES-02: a randomized controlled phase 3 trial testing imlifidase treatment in anti-GBM disease – outcomes and post hoc analysis

👉Anti-GBM disease remains one of the most devastating nephrological emergencies.
👉Could rapid antibody depletion with imlifidase improve outcomes beyond current standard therapy?
💬 Mårten Segelmark

[ERA - European Renal Association @ERAkidney]

1/6 🧵 #ERA26 - High impact clinical trials in Nephrology. #ChallengeYourThinking
🪑: Mario Gennaro Cozzolino @MarioCozzolin19; Kaitlin Mayne

Effects of SGLT2 inhibitors on erythropoiesis and iron homeostasis: a systematic review and meta-analysis exploring how these agents may raise Hb/Hct beyond simple hemoconcentration.
💬 Speaker: Michele F. Eisenga

[ERA - European Renal Association @ERAkidney]

🔥During #ERA26 Late-Breaking Clinical Trials 2, @AgarwalRajivMD presented efficacy and safety of finerenone in patients with chronic kidney disease: a pooled individual participant data analysis (INFINITY)♾

Finerenone trials included a broad CKD population encompassing a range of disease aetiologies and levels of glycemia, eGFR & albuminuria

[ERA - European Renal Association @ERAkidney]

🔥Last presentation in high impact clinical trials in Nephrology #ERA26

⏩Efficacy and Safety of SGLT2 Inhibitors in Alport Syndrome: A Multicenter Prospective GLIFAS Study

🎙️Presented by Domenico Santoro

🧬Alport syndrome results from COL4A3–5 variants affecting GBM collagen

[ERA - European Renal Association @ERAkidney]

1st simultaneous publication of the day #ERA26 @HyperAHA

📍Safety and Synergy of Finerenone and Empagliflozin in Lowering Blood Pressure

✍️By @AgarwalRajivMD and co

https://t.co/5mHZTDn5bn

[Arunkumar @Arunkr_Dr]

🚨 High-Impact Clinical Trial at #ERA26

FIND-CKD explores whether the benefits of finerenone can extend beyond DKD to the large population with non-diabetic CKD

#FINDCKD #CKD #Nephrology

[Arunkumar @Arunkr_Dr]

📊 #TURING results #ERA26

✅ Ritux delayed relapse
✅ 3 × 1 g doses over 26 wks maintained remission for >2.8 years
✅ Higher CR rates in FSGS (21/30 vs 11/26; p=0.037)
✅ Faster prednisolone taper feasible

Another important step toward steroid-sparing Rx in podocytopathies

[Andreas Kronbichler @AKronbichler]

It was a huge pleasure to work alongside a global team and contribute to the CKD series published in @TheLancet (article 1 out of 3).

https://t.co/2yYXOx2aC3

[ERA - European Renal Association @ERAkidney]

Wearable devices for vascular access monitoring
#ERA26

Technology at the service of AVF monitoring:
📌 impedance
📌 thermal flow
📌 thrill sensor

Speaker: Maurizio Gallieni @MGallieni

[KDIGO @goKDIGO]

KDIGO and Nexus Healthcare Education have a new 3-part webinar series on the complex relationship between CKD and hypertension and its implications for patient care.

Join us on June 15 for Part 1 of the series, which focuses on the role of aldosterone in the decline of kidney function in people with CKD. Register: https://t.co/9UDAKY4SiO

Led by Professors David Wheeler, Adeera Levin, and Hiddo Heerspink, the series explores practical strategies for translating emerging science into better patient care.

Learn more: https://t.co/Iz4mWsKEca

#CKD #hypertension

[ERA - European Renal Association @ERAkidney]

CME4: Hemo and PD
#ERA26 @ERAkidney

Introduction by Manferd Hecking and Rusksana Shroff @RukshanaShroff chairing
EuDial working group aims to improve and innovate dialysis treatments and this CME aims to challenge your thinking!

1/9
🗣️Mabel Aoun @MabelAoun kicks off the session with the talk ‘Evidence Based Medicine (EBM) use of laboratory tests in PD and HD’

▶️Is there any true evidence in this area?
Measuring pre and post-HD BUN, creatinine, and electrolytes is an evidence free area
Certainty in evidence -GRADE approach to access quality of evidence. Based on the quality if data and publications, RCTs and observational studies can be ⬆️or ⬇️ graded.
BUT clinical judgment and expertise along with patients' values and understanding shape clinical practice. Effective health care also has to be cost-effective.

[Arunkumar @Arunkr_Dr]

#ERA26 #IgG4RelatedDisease by Dr Augusto Vaglio

🔹When thinking of #IgG4RD and the kidney, think beyond TIN.
🔹Renal involvement spans TIN, MN, and RPF, with distinct clinical phenotypes and presentations.
🔹Hypocomplementemia and elevated IgG4 provide valuable diagnostic clues

[ERA - European Renal Association @ERAkidney]

Prevention strategy!
#ERA26