https://t.co/yo0ADqaJHP
Thrilled to share our new study! We show that mirusviruses include lineages packed with spliceosomal introns and likely replicating in the nucleus of unicellular eukaryotes—a sharp contrast to most large eukaryotic viruses that replicate in the cytoplasm.
1/7 What happens when specialists of methanogens join forces with experts in archaeal viruses? Happy to share my last study with @SGribaldo, @mkrupovic, guillaumeborrel, @institutpasteur funded by @ANR. Link: https://t.co/z2HfH9SXvs
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7/7 The characterization of this vast repertoire of viruses paves the way toward a better understanding of their role in regulating methanogen communities globally as well as the development of much-needed genetic tools. Stay tuned for further developments!
6/7 Methanogens are widespread in the human gut. Are there any signatures of viral adaptation to the gut environment? Yes! We found an enrichment of Ig-like domains and Diversity Generating Retroelements (DGRs) in gut viruses, which can help virions attach to the mucosal layer.