Check out our work in AI-guided chemistry, now out in @Nature, enabling novel chemical synthesis with detailed protocols and feasibility!
Thanks to my co-first author Haote, Profs Newhouse, Batista, authors & @Boehringer!
@Yale News: https://t.co/QbekDADy3r
Publication: https://t.co/MtFfqAg6vt
Yale chemists have developed a new digital framework they say will speed up drug discovery and other breakthroughs. MOSIAC is an open-source AI-guide for researchers navigating the complex world of chemical synthesis. Learn more in this article https://t.co/nclRePDjay.
Check out our work in AI-guided chemistry, now out in @Nature, enabling novel chemical synthesis with detailed protocols and feasibility!
Thanks to my co-first author Haote, Profs Newhouse, Batista, authors & @Boehringer!
@Yale News: https://t.co/QbekDADy3r
Publication: https://t.co/MtFfqAg6vt
New heterocoupling to make complex morpholine is unlocked! 🚀🔬Check it out!
Aziridine–Epoxide Heterocoupling: A Straightforward Approach to Stereoselective Synthesis of Complex Morpholine Derivatives | Journal of the American Chemical Society https://t.co/dfs6wQwB8d
Direct C–H alkylation could be a very useful strategy for rapidly building molecular diversity, including 3° & 4° carbon centers. Congrats Subham & Gaurav on developing Light-Induced Pd-Catalyzed Allylic C–H Alkylation of Internal Alkenes! out in @J_A_C_S
https://t.co/HnqDfzs7bk
🚨 Two new C–H bonds borylated – no metals, no catalysts, just light!
Excited to share our work, now out in @J_A_C_S: Site-selective β- & γ-C–H borylation of amines, featuring a new tether for elusive β-functionalization.
Grateful to Nitish, Tong & Vlad!
https://t.co/QoAsIaLJFe
Please join us in congratulating Sumon, Nitish, & Tong for achieving photoinduced, site-selective β- and γ-borylation of amines using a new, easily installable/ removable radical translocating group, enabling late-stage derivatization. Out now in @J_A_C_S
https://t.co/JVvLY2gF4m
Transition-Metal-Free Site-Selective β- and γ-C–H Borylation of Aliphatic Amines | Journal of the American Chemical Society @GevorgyanLab@UT_Dallas https://t.co/jE3FT7ecqL
Aryl radical-mediated dual HAT enables direct CDC of aldehydes & alkenes to form skipped enones with high chemoselectivity! Congrats, Sidhant & Pramod, for developing Ni-Catalyzed Cross-Dehydrogenative Coupling toward Skipped Enones, now out in @J_A_C_S
https://t.co/fWWMusfC2m