Dr. Mariana Vargas Caballero

Associate Professor of Neuroscience 🧠 University of Southampton. Electrophysiologist. I 🖤 synapses & ion channels. #LatinaInSTEM 🇲🇽🇬🇧 Mum. My own views.

[Dr. Mariana Vargas Caballero @synapseMVClab]

New paper for the lab!
"Functional effects of haemoglobin can be rescued by haptoglobin in an in vitro model of subarachnoid haemorrhage." #JNeurochem Thanks to all authors for the great team effort @WarmingHannah @KatrinDeinhardt
#patchclamp

[Dr. Mariana Vargas Caballero @synapseMVClab]

@ElenaRF @josefagbom @Tracy_Henning27 @UWTSD Congratulations!!! 🇲🇽🇬🇧 How are you going to celebrate? This year in Sept will be my very own 24+24 and I'm thinking of ideas!?

[Dr. Mariana Vargas Caballero @synapseMVClab]

@EBrookesNeuro @KatrinDeinhardt We are the lucky ones!

[Dr. Mariana Vargas Caballero @synapseMVClab]

Congratulations Hannah Warming on passing your PhD viva 🎉🎉🎉 Thanks to examiners Vincent O'Connor and Adrian Parry-Jones and co-supervisors Ian Galea and Diederik Bulters. Grateful to Kerkut Trust and Institute for Life Sciences @WarmingHannah 🎉🎉🎉

[Dr. Mariana Vargas Caballero @synapseMVClab]

We are grateful to our funders @ARUKscientist and Kerkut Trust. #alzheimersresearch

[Dr. Mariana Vargas Caballero @synapseMVClab]

Congratulations Lauren McNicholas on passing your PhD viva 🎉🎉👏🏽👏🏽👏🏽. Thanks to @KatrinDeinhardt for co-supervising, Ole Paulsen and Salah Elias for being examiners.#electrophysiology @LaurenMcN1 @OlePaulsen2 @theeliaslab

[Emily Brookes @EBrookesNeuro]

I’m excited to announce that I have 2 fully funded, 3.5 year PhD studentships to join my lab next year. Please take a look if you fancy some neuroepigenetics fun on the south coast! @unisouthampton @sotonbiosci Details below

[Dr. Mariana Vargas Caballero @synapseMVClab]

@EBrookesNeuro @SouthamptonCC @alanwhiteheadmp I hope this gets resolved immediately for you. It’s hard enough to move, start a new research group and wait so long for a school place.

[Dr. Mariana Vargas Caballero @synapseMVClab]

@parkrunUK Me! Did my 50th #parkrun today ���🏽 thanks @parkrunUK and @Sotonparkrun volunteers for keeping it going 🙌🏽

[Andrew Penn @ACPenn6]

A new paper from our lab reveals the effect of gain- and loss-of-function GluN2B mutations on synaptic function. The differences in NMDA-EPSCs mediated by synaptic GluN1/2B mutants are lost when the mutated subunits assemble with GluN2A into triheteromers

https://t.co/95NzWngcot

[Dr. Mariana Vargas Caballero @synapseMVClab]

@neuronancy_ 👏🏽👏🏽👏🏽 these are tricky, but once you have them, a dream for voltage clamping native ion channels.

[Dr. Mariana Vargas Caballero @synapseMVClab]

@BBCInOurTime @BBCRadio4 Fascinating stuff @MarkSulAstro 👏🏽👏🏽👏🏽 @unisouthampton

[In Our Time @BBCInOurTime]

Coming up: how collisions of neutron stars, billions of years ago, created all the gold in the world https://t.co/40uRu7cQhQ 9am @BBCRadio4

[SussexNeuro @SussexNeuro]

Abeta effect on synaptic vesicle pools: latest paper from a fantastic collaboration with @KStaras and first authorship from @Luca_Biasetti along with collaborations with @cathnaledi @synapseMVClab. A brilliant team effort. @The_MRC @SussexNeuro https://t.co/hx1kgaZMn9

[Dr. Mariana Vargas Caballero @synapseMVClab]

Co-led with @OlePaulsen2. Following on from key papers published by Ole's lab including work by @KohlLab showing that CA1 synapses with left CA3 input have a higher proportion of GluN2B-NMDARs and are more plastic. Fantastic work by co-authors Olivia Shipton and Clara Tang.

[Dr. Mariana Vargas Caballero @synapseMVClab]

Thrilled to share our new paper! Our results suggest that hippocampal CA3‑CA1 synapses with presynaptic axon originating in the left CA3 are selectively vulnerable to Aβ and that a genetic knock out of tau protein protects them. https://t.co/OsdH438u4M

[Dr. Mariana Vargas Caballero @synapseMVClab]

@josefagbom @Embamexru @InovaUK What a pleasure to visit the Mexican embassy and meet amazing women including the ambassador Josefa González Blanco. Motivating, inspiring and empowering girls and women in #STEM… I’m in!