Christine

Tech Support Specialst in SoCal.
GLP-1s 💉Hiking 🥾 Australian Cattle Dogs 🐕 Books 📚 and Tech.

[Brandon Katz @Great_Katzby]

I'm a former critic. Here's my analysis on the upcoming #TheEndofOakStreet:

If the dog survives, the movie rules. If the dog dies, it sucks.

[Christine @TechLifeNCoffee]

@Great_Katzby I need to know what happens to the dog! I have an Australian Cattle Dog that looks very similar to this dog. If he dies in the movie, I cannot watch it.

[The Best @TheBestqueenx]

This is what the first payment on a 30-year home loan looks like.

[erika @yeeeerika]

the human spirit was not designed for this many passwords

[Christine @TechLifeNCoffee]

This! #AI

[Massimo @Rainmaker1973]

A new study has shown that Raccoons are showing early signs of domestication

The University of Arkansas found that urban raccoons have smaller snouts, a sign of domestication syndrome.

[On The Pen™ @ManOnThePen]

Remember when GLP-1 haters said these meds were “just vanity drugs”?

Now we’re seeing data suggesting people on Ozempic and Mounjaro may have LOWER cancer progression, LOWER mortality, and even reduced breast cancer risk.

Heart disease. Sleep apnea. Addiction behaviors. And now potentially cancer outcomes too.

Funny what happens when we treat obesity as the chronic disease that it is.

[Christine @TechLifeNCoffee]

Save 5% on GLP-1's and other peptides and wellness meds at Belle. https://t.co/QKTThcMErr

[Christine @TechLifeNCoffee]

Such a great video!
#cortisol #hormones #walking
https://t.co/g6WBSVWMjz

[Sweatpants & Coffee @SweatpantsCafe]

What’s going on here?? ☕️🫪

[On The Pen™ @ManOnThePen]

The medical community can only scream and shout about the lack of of safety around compounded GLP-1 so much before patients using them just feel gaslit.

They’re down meaningful amounts of weight, improved their biomarkers, and taken their lives back.

[Christine @TechLifeNCoffee]

@dog_rates Poor Spear! 😩😩

[Christine @TechLifeNCoffee]

😆😆😆

[WeRateDogs @dog_rates]

This is Spear. He is being forced to leave his grandma's house against his will. You know who would never do this to him? Grandma. 13/10

[Michael Albert, MD @MichaelAlbertMD]

“25–40% of weight loss is lean muscle” is not accurate.

What those analyses (STEP, SURMOUNT) actually report is loss of lean mass on DEXA—and that is not the same thing as skeletal muscle.

DEXA divides the body into:
🔹Fat mass
🔹Bone
🔹Lean soft tissue

That “lean” bucket includes water, glycogen, organs, connective tissue, and muscle. It is highly dynamic and shifts with caloric restriction, hydration, and glycogen depletion.

So when you see “25–40% lean mass loss,” what you’re really seeing is: ➡️ fat-free tissue change—not isolated muscle loss

If you want to measure actual skeletal muscle, you need CT or MRI (cross-sectional area, muscle volume, etc.).

And here’s the key point:
There is no consistent CT/MRI evidence showing that GLP-1–based therapies cause disproportionate skeletal muscle loss relative to expected weight loss physiology.

What we do know:
🔹All weight loss (diet, surgery, pharmacotherapy) includes some lean/FFM reduction
🔹The ~25–40% range is well-described baseline physiology, not a GLP-1-specific signal
🔹The dominant effect remains preferential fat mass loss with significant metabolic benefit

So this isn’t a drug-specific muscle-wasting phenomenon.
It’s a misinterpretation of what DEXA actually measures.

If we’re going to have strong opinions here, we should at least be precise about the difference between: lean mass, fat-free mass, and skeletal muscle

Because those are not interchangeable terms—and treating them like they are leads to bad conclusions.

[Christine @TechLifeNCoffee]

😆😆😆

[garshmo @garshmo]

Matthew McConaughey in kindergarten trying to spell his own name

[National Park Service @NatlParkService]

Don’t go chasing waterfalls...cautiously approach and be careful of slippery conditions. In fact, you may just want to stick to the rivers and lakes that you’re used to.

[Christine @TechLifeNCoffee]

On April 30th, 2026, the FDA moved to exclude GLP-1s from the 503B "Bulks List." How will this affect 503A pharmacies? #glp1 #compoundtirzepatide #compoundsemaglutide #503bpharmacies
https://t.co/zHNQvFZTZp

[Christine @TechLifeNCoffee]

https://t.co/NXibL96ebJ

[Christine @TechLifeNCoffee]

Nevermind, I see the issue on your status page. https://t.co/iPa2CJLefz

[Christine @TechLifeNCoffee]

@OpenAI are you aware of an issue with downloading PDFs and other files generated by ChatGPT? It just sits at "starting download" and nothing happens. I did find a workaround on Reddit - but it is not user friendly. Thanks!