Hypothesis

Asking questions! Wondering!

[Hypothesis @Test_Hypotheses]

Maechling Myopia - the world as an Erlenmeyer flask!

A world where formulas pretend to be reality!

H2O is a formula!

Water as we encounter it in reality is never pure H2O!!

And every synthetic chemical product will contain finite and measurable impurities!!

[Hypothesis @Test_Hypotheses]

@SamaHoole Sama

Your preachings are a disservice to public health!

A meat diet maybe a short term escape from DM2 but in the long term it will cause serious cardiovascular disease!

If you feel comfortable with advising people to eat a lethal diet - continue your deadly preachings!

[Hypothesis @Test_Hypotheses]

@SamaHoole Sama

Your preachings are a disservice to public health!

A meat diet maybe a short term escape from DM2 but in the long term it will cause serious cardiovascular disease!

If you feel comfortable with advising people to eat a lethal diet - continue your deadly preachings!

[Hypothesis @Test_Hypotheses]

Maechling Myopia - the world as an Erlenmeyer flask!

A world where formulas pretend to be reality!

H2O is a formula!

Water as we encounter it in reality is never pure H2O!!

And every synthetic chemical product will contain finite and measurable impurities!!

[Simon Maechling @simonmaechling]

What if, for a few minutes, you could see the world through the eyes of a chemist?

You might discover that the greatest problem isn’t chemistry itself, but the stories we’ve come to believe about it.

For years, I’ve watched something curious happen.

People have become increasingly afraid of the word chemical.

As a chemist, that’s difficult to understand - not because I work with chemicals, but because everything is chemistry.

When I look at a glass of water, I don’t see something “natural.” I see H₂O.

When I look at a banana, aspirin, caffeine, vitamin C, or the fragrance of a rose, I don’t divide them into “good” and “bad” chemicals. I see molecules with structures, properties, and interactions.

Chemistry teaches you something that changes how you see the world forever.

Nature doesn’t know the difference between natural and synthetic.
Atoms don’t care where they came from.

A molecule has no memory of whether it was made inside a plant or inside a laboratory. It behaves according to the same laws of physics and chemistry.
That’s why chemophobia feels so strange to me.

People often ask whether something is “full of chemicals.” To a chemist, that’s like asking whether music is full of notes.
Of course it is.

Everything around us is made of chemicals, including us.

What matters isn’t whether something is a chemical.
What matters is which chemical, how much of it, how we’re exposed to it, and what the evidence says.

That’s how toxicology works.
That’s how medicine works.
That’s how chemistry works.

Yet somewhere along the way, we’ve started judging molecules by their origin instead of their properties.

Natural has become synonymous with safe.
Synthetic has become synonymous with dangerous.

The real cost of chemophobia isn’t just confusion.
It’s that fear replaces curiosity.

People become suspicious of medicines before understanding them.
They reject innovations before examining the evidence.

Young people begin to associate chemistry with pollution rather than discovery.

That saddens me.

Because chemistry has given humanity clean drinking water, antibiotics, fertilizers, batteries, polymers, vaccines, semiconductors, modern materials, and countless medicines that millions of people rely on every day.

Its greatest success may also be its greatest weakness.

Chemistry has become so woven into everyday life that most people no longer notice it.

We notice rockets launching into space.

We rarely notice the chemistry that keeps food on supermarket shelves, powers our phones, or allows a child with diabetes, cancer, or an autoimmune disease to live a normal life.

I didn’t become a chemist to make the world more “artificial.” I became a chemist because I wanted to understand how the world works.

The more chemistry I learned, the less mysterious and the less frightening the world became.

That’s what chemistry offers us.

Not reasons to be afraid.
But the tools to replace fear with understanding.

[Hypothesis @Test_Hypotheses]

My friend Leon Elon?

[Hypothesis @Test_Hypotheses]

If I were as rich as Elon I’d buy out Bayer and fire Maechling!

[Simon Maechling @simonmaechling]

If I were as rich as Elon Musk, I’d invest less in rockets and more in helping people understand science.

Because the biggest barrier to progress isn’t technology.

It’s understanding.

[Hypothesis @Test_Hypotheses]

It’s not just the quality but also the quantity and frequency!

Dumbshit fatty brain!!

[Sama Hoole @SamaHoole]

1900s: "Butter is wholesome. Everyone cooks with it."
1911: "Try Crisco. Modern, clean, better than old-fashioned lard."
1960s: "Butter clogs your arteries. Switch to margarine."
1980s: "Margarine is the heart-healthy choice. Spread it thick."
1990s: "Those margarine trans fats are quietly killing people."
2004: "We are banning the trans fats we told you to eat."
2014: "Butter is back. We may have got this one wrong."
2020s: "Grass-fed butter is a health food now."

You: realising the food never changed once. Only the advice did, every decade, always with total confidence, and always with something new to sell you.

[Hypothesis @Test_Hypotheses]

Garbledegook again from the master of stupetalk!

Aging and death are inevitable and not negotiable!

Disease is highly negotiable at individual, societal and global levels!

And - as Simon knows too well - disease is big BIG Pharma business!!

[Simon Maechling @simonmaechling]

The conspiracy theory assumes health is the default and medicine is the business.

Reality is the opposite.

Disease, aging, and death are the defaults.

Medicine is humanity’s attempt to negotiate a better deal.

[Hypothesis @Test_Hypotheses]

The human skin - even when maximally melanized - was not made for the sun!

On the contrary- it was made to defend itself AGAINST the sun!

Despite all its defense mechanisms there is only one effective way for it to survive!

GET OUT OF THE SUN!!

[Sama Hoole @SamaHoole]

Hours in the midday sun, weeks on end. Tanned like a conker. Not one peel.

Six years ago, before I cut seed oils, the sun would barely touch me and I'd be peeling within days.

Correlation isn't causation, sure. Until you learn seed oils get stored in your skin and oxidise under UV. That reaction is the burn.

Cut the oils. Give it two years. Your skin stops flinching at the sun it was built for.

[Hypothesis @Test_Hypotheses]

Sama

what happened????

You quit your carnivore rants for a great post!

Keep it up!

Forget that carnivore crap!

[Sama Hoole @SamaHoole]

We have been trained to treat the smallest hunger as an emergency. For all of human history it was the most ordinary state there was.

Every religion built fasting into its calendar. Lent, Ramadan, the Orthodox fasts that fill half the year. Going without food was treated as cleansing, even holy.

Every hunter fasted between kills, sometimes for days, then ate to bursting when the hunt came good. Feast and famine was the human rhythm long before three meals a day were invented.

The body is built precisely for the gap. Run it low and it turns to its own fat for fuel, sharpens the mind, and clears out worn cells.

Then the food industry arrived and crowned breakfast the most important meal of the day, a slogan dreamed up to sell cereal.

It taught you to dread the space between meals. To carry snacks. To eat six times a day. To treat plain hunger as a medical event.

Every culture in history knew how to be hungry for a while and be perfectly fine.

We are the first people ever sold the idea that an empty stomach is a problem, by the very people who profit each time you fill it.

[Hypothesis @Test_Hypotheses]

Getting a transmural MI or a paralyzing stroke won’t be boring!

I promise!

And 10 years from now the reaper will find you!!

And have his beef with you!

[Sama Hoole @SamaHoole]

Getting lean on carnivore is almost boring.

You cannot really overeat a ribeye. Protein and fat fire the "done" signal long before you've done any damage.

There's no bottomless snacking, because the food satisfies you and then declines to be interesting.

Meanwhile the muscle stays put, because you're swimming in protein and lifting heavy.

A deficit you never have to count, holding muscle you never have to fight for.

They don't put that bit on the poster.

[Hypothesis @Test_Hypotheses]

Sorry

this is a straw man story!

I can’t picture Simon listening to anybody for even s second

how could he

he is constantly mouthing off

AI bull!

[Simon Maechling @simonmaechling]

At dinner last night a man explained that the local rice was drowned in glyphosate.

He spent 20 minutes warning me about chemicals in food.

Then he stepped outside and smoked a cigarette.

I’ve never seen a better demonstration that people don’t fear risk.

They fear stories.

[Hypothesis @Test_Hypotheses]

Scientists don’t develop technologies!

Scientists test hypotheses!

Big Pharna, anong others, develop technologies and their minions like Simon Maechling push them via propaganda in their AI assisted X posts!

[Hypothesis @Test_Hypotheses]

Scientists don’t develop technologies!

Scientists test hypotheses!

Big Pharna, anong others, develop technologies and their minions like Simon Maechling push them via propaganda in their AI assisted X posts!

[Simon Maechling @simonmaechling]

A reminder that scientists spent decades developing technologies that… checks notes… reduce disease, increase food production, and save lives.

And somehow that’s become controversial.

[Hypothesis @Test_Hypotheses]

@CaimanVigilante @simonmaechling Incorrect! The evidence of today is the trash of tomorrow! The is no truth in science! Only in logic!

[Hypothesis @Test_Hypotheses]

Sama

Get a bit more educated!

Even if you block all glucose intake a cancer will ���steal” glucose via gluconeogenesis!

And the main substrate for gluconeogenesis are amino acids - from either ingested protein or broken down endogenous proteins, primarily muscle!

[Sama Hoole @SamaHoole]

We worked out, decades ago, exactly which fuel many cancers prefer.

Glucose. They guzzle it, ferment it even with oxygen right there, and lean on that sugar to grow. It has a name, the Warburg effect, and it's been in the textbooks since the 1920s.

So, knowing the tumour's favourite food, here's the plan:

- Demonise the diet that lowers it
- Pancakes for breakfast
- Biscuits in the day room
- "Build you up" sugar drinks
- Jelly and ice cream as a treat
- Tut at anyone who asks about cutting the sugar

We found the fuel. Then we built the catering trolley to deliver it.

To be clear, since it matters: keto is not a cure, and nobody serious says it is. It's being tested as an adjunct, alongside chemo and radiotherapy, mostly in small glioblastoma trials, and the evidence is still early. Anyone promising more is selling something.

But there's a difference between "we don't yet know if starving the tumour helps" and "let's actively feed it custard."

One is honest uncertainty. The other is on the lunch menu.

[Hypothesis @Test_Hypotheses]

Simon

Could you give us a few details and insights regarding anti-science theories along with citations and sources?

Or shall we be stuck with the belief you are building straw men or are fighting wind mills?

Thanks from a published molecular neurobiologist!!

[Simon Maechling @simonmaechling]

Anti-science theories have a built-in defense mechanism.

Show evidence?
“It’s fake.”

Show a study?
“Big Pharma paid for it.”

Show 100 studies?
“They bought them all.”

The goal isn’t to test a belief.
It’s to protect it.

[Hypothesis @Test_Hypotheses]

WTF??

Are you inebriated?

Senseless gobbledygook!!

Go sleep it off on a sidewalk somewhere!

Not here on X!!

[Simon Maechling @simonmaechling]

People like to think beliefs follow evidence.

More often, evidence follows beliefs.

[Hypothesis @Test_Hypotheses]

Data centers gobbling up water and spewing diesel fumes is the progress we’ve all been praying for!!

And perhaps AGI will grant humans continued existence!

Hail progress!!

[Simon Maechling @simonmaechling]

Humanity survived before science and technology transformed our lives.

But billions didn’t.

Progress is what happens when we stop accepting suffering as inevitable.

[Hypothesis @Test_Hypotheses]

That animal looks so happy, content and healthy but Sama can’t wait to kill and devour it!

Pure EVIL!

[Sama Hoole @SamaHoole]

There is an animal that:

- Walks to her own food on her own legs
- Eats grass humans cannot digest
- Drinks rainwater that falls whether she's there or not
- Needs no pesticide, herbicide, irrigation, factory, or refinery
- Builds topsoil 30 to 50 times faster than nature
- Fertilises the ground that grew her dinner
- Supports dozens of wildflower, insect, and bird species
- Reproduces herself once a year, free of charge
- Produces meat, milk, butter, cheese, cream, leather, tallow, suet, bone, and broth
- Delivers complete protein, every fat-soluble vitamin, haem iron, B12, zinc, and choline
- Has done all of this, on the same hillsides, for ten thousand years
- Runs on sunlight

And we have spent thirty years being told this animal is the problem.

The fermentation tank in Singapore, drawing power from a fossil fuel grid, fed on monoculture soy from a deforested Brazilian plain, producing a beige paste with twenty-two ingredients, is the solution.

The audacity is breathtaking.