UCLA Vascular Biology Lab

The labs of Drs. Kristina Bostrom and Yucheng Yao @dgsomUCLA study the role of bone morphogenetic proteins and their inhibitors/receptors in vascular biology.

[Xinjiang Cai, MD, PhD 🫀 @XinjiangCai]

We are happy to share our newly published viewpoint, "Cardioprotective Mechanisms of Sodium-Glucose Cotransporter-2 Inhibitors: What Have We Learned So Far?", published today in @JACCJournals JACC: Advances.

https://t.co/KU4bfoMENB

[ATVB: An AHA Journal @atvbahajournals]

BMP binding by matrix Gla protein (MGP) is essential for limiting aortic fibrosis but not the anti-calcific effects.
@UCLAVascularBio @XinjiangCai @Wu_Xiuju @Zhanglily19 @juliyan_g
https://t.co/7dk4ON148W

[UCLA Vascular Biology Lab @UCLAVascularBio]

Fresh from the press - please check out our article published online by ⁦@MolMetab⁩ today.

⁦@zhanglily19⁩ ⁦@XinjiangCai⁩ ⁦@dgsomucla⁩

Regulating the Cell Differentiation Trajectory of Progenitor Cells in Adipose Tissue Fibrosis https://t.co/TBeuHnbOBM

[UCLA Vascular Biology Lab @UCLAVascularBio]

Check out our paper on AVM and hemorrhagic telangiectasia type 2 published in Circulation today!

Arterial-Lymphatic-Like Endothelial Cells Appear in Hereditary Hemorrhagic Telangiectasia 2 and Contribute to Vascular Leakage and Arteriovenous Malformations https://t.co/Nj1n6jVQek

[UCLA Vascular Biology Lab @UCLAVascularBio]

Hot off the press from our lab!

⁦@CircAHA⁩ ⁦@DOM_UCLA⁩

Arterial-Lymphatic-Like Endothelial Cells Appear in Hereditary Hemorrhagic Telangiectasia 2 and Contribute to Vascular Leakage and Arteriovenous Malformations | Circulation https://t.co/Nj1n6jVQek

[UCLA Vascular Biology Lab @UCLAVascularBio]

JCI in press - our most recent paper on EndMT and cerebral AVMs. It will be a fantastic read!

@UCLAHealth @DOM_UCLA @dgsomucla @uclaCVfellows

JCI - Inhibition of endothelial histone deacetylase 2 shifts endothelial-mesenchymal transitions… https://t.co/5iZoxlhMkm

[UCLA Vascular Biology Lab @UCLAVascularBio]

Check out our most recent publication on fibrosis in patients with Fontan Procedure published in
@JACCJournals. In collaboration with our adult congenital heart disease and transplant surgeon teams @dgsomucla @DOM_UCLA @UCLAHealth

https://t.co/KZSwFHVqP2

[UCLA Vascular Biology Lab @UCLAVascularBio]

Check out our new publication in JCI Insight - CDK1 inhibition reduces osteogenesis in endothelial cells in vascular calcification @vascularbiology @JCI_insight @DOM_UCLA @dgsomucla

https://t.co/tiOZluxizB

[UCLA Vascular Biology Lab @UCLAVascularBio]

Please join us at the next NAVBO InFocus session on Thursday 01/25/24. Dr. Li Zhang @zhanglily19 from our lab will present her recent report on the role of matrix Gla protein in adipogenesis.@DOM_UCLA @dgsomucla

[NAVBO @vascularbiology]

Join us TOMORROW! #InFocusSession 👇🤓🫀📈

👉👉 Register: https://t.co/Lh6PTcutol

[UCLA Vascular Biology Lab @UCLAVascularBio]

Our paper exploring brown adipose tissue differentiation regulated by Matrix Gla Protein has just been published by ⁦@MolMetab⁩.

Congratulations to ⁦@zhanglily19⁩ from our lab at ⁦@DOM_UCLA⁩ ⁦@dgsomucla⁩.
https://t.co/1d7V5etKWI

[UCLA Vascular Biology Lab @UCLAVascularBio]

Dr. Li Zhang @zhanglily19 from @UCLAVascularBio @dgsomucla presented her research on the role of matrix Gla protein in brown adipose tissue development at the Vascular Biology 2023 meeting.

Five lab members attended the @vascularbiology meeting. It was a fantastic experience!

[UCLA Vascular Biology Lab @UCLAVascularBio]

Aurora Kinase A Regulates Cell Transitions in Glucocorticoid-Induced Bone Loss. Take a look! https://t.co/8RrP6pcnCv

[UCLA Vascular Biology Lab @UCLAVascularBio]

We used publicly available databases to study the relationship among COVID-19, endothelial cells, and Pulmonary Fibrosis

https://t.co/i6npaFhiLi

[UCLA Vascular Biology Lab @UCLAVascularBio]

Just published in the Special Issue GSK3 as a Master Regulator of Cellular Processes

- GSK3β Inhibition Ameliorates Atherosclerotic Calcification.
@MDPIOpenAccess
@IJMS_MDPI

https://t.co/QZvwytXRKr

[UCLA Vascular Biology Lab @UCLAVascularBio]

Hot off the press!

“… the results suggest that glucocorticoids suppress osteogenic capacity and cause bone loss at least in part through previously unrecognized osteoblast–endothelial transitions.”

@endothelialnews

https://t.co/DV2B2sAhHr

[UCLA Vascular Biology Lab @UCLAVascularBio]

A new perspective on pulmonary fibrosis - take a look at our recent paper published online in the European Respiratory Journal @ERSpublications

Regulating the cell shift of endothelial cell-like myofibroblasts in pulmonary fibrosis

https://t.co/vXRfahZFsr

[UCLA Vascular Biology Lab @UCLAVascularBio]

Happy Holidays! We would like to introduce to you our newest lab members! @uclachem @dgsomucla @UCLACollege

Jocelyn Ma is a brilliant UCLA undergraduate majoring Biochemistry. She and Jaden are both working on the Matrix Gla Protein.

Here is her introduction and a fun photo.

[UCLA Vascular Biology Lab @UCLAVascularBio]

Happy Holidays! We would like to introduce to you our newest lab members! @MicrobioUcla @dgsomucla @UCLACollege

This is Jaden Ji - a talent third year UCLA undergraduate majoring Microbiology, Immunology, and Molecular Genetics.

Here is her introduction and a fun photo.

[UCLA Vascular Biology Lab @UCLAVascularBio]

Come to visit us at the poster session at noon today! @vascularbiology @ivbm2022. Poster #3122 #3137 #3138.

Topics range from cardiac transition from adipose derived cells, congenital heart disease, to vascular calcification! @DOM_UCLA @dgsomucla @UCLAVascularBio