Dr Sreenidhi dhambolam

Urology resident

[Kawsar @Kawsar_Ai]

GOODBYE TO ASTROLOGERS.

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[Nav Toor @heynavtoor]

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[Dr Sreenidhi dhambolam @urolsreeni]

@sbinhamrii I think guidewire went submucosally!!

[Dr Rishabh Jain @DrRishabhOnco]

MRI before prostatectomy isn’t just staging… it’s prognostic.

New meta-analysis in JAMA Oncology shows MRI predicts outcomes independently.

🧵

📌 Study: Pretreatment MRI as prognostic factor after radical prostatectomy
📊 40 studies | 24,941 patients

👨‍⚕️ Population
Men undergoing radical prostatectomy with pre-treatment MRI

⚔️ Key MRI features → Strong outcome predictors

🔴 Extraprostatic extension (mrT3a)
•BCR: HR 2.16
•Metastasis: HR 3.18
•Cancer-specific mortality: HR 10.9 (!!)

🔴 Seminal vesicle invasion (mrT3b)
•BCR: HR 2.74
•Metastasis: HR 5.58

📊 Quantitative MRI also matters
•PI-RADS 4–5 → HR ~2.1
•Tumor ≥20 mm → HR ~2.35
•Low ADC → HR ~2.4

💡 Key insight
MRI adds independent prognostic value beyond PSA, Gleason, and pathology

👉 Not just imaging
👉 A biologic risk signal before surgery

⚠️ Practice-changing angle
MRI T-staging may be stronger than DRE-based clinical staging

→ Enables better pre-op risk stratification
→ Potential for treatment intensification / de-escalation

🎯 Takeaway
If you’re still using MRI only for staging…
You’re underusing it

MRI = prognosis + decision-making tool

🔖 Save this for clinic discussions

📖 Full paper in comment ⬇️

#OncoTwitter #MedTwitter #ProstateCancer #UroOncology @OncoAlert @myesmo @esmo_open @asco

[Jad Najdi @najdi_jad]

Take-home messages from an outstanding update on mHSPC by Dr.
@dmukherji

[Yüksel Ürün @DrYukselUrun]

ESMO Clinical Practice Guideline: Local and locoregional prostate cancer!
@myESMO @APCCC_Lugano @AttardLab @Ecastromarcos @stefanofanti4 @Silke_Gillessen @Prof_Nick_James @piet_ost @MarkARubin1 @ChrisSweens1 @Tilki_De @ZilliThomas @alison_tree @OncoAlert
https://t.co/jbgi5KBYxs

[Urological Society of India 🇮🇳 @usioffice]

USICON 2025.
The biggest urology conference in South Asia started from today 9 Jan. Witnessing ground breaking research and cutting edge technology till 12 Jan 2025.

[Dr Sreenidhi dhambolam @urolsreeni]

@Usicon2025 @chennaitradecenter
@eposter @endourology @rirs

[gaganprakash @drgaganprakash]

Impactful start to #SIU2024 this morning with @UroDocAsh highlighting likely shifts in MIBC landscape..relevant for organising treatment pathways @TataMemorial & @ACTREC_TMC @VedangMurthy @dramandeeparora @AmitJos93188352 @docpriyamvada @IBCG_BladderCA

[Dr Sanjay Kulkarni @sanjaybkulkarni]

#SIU2024NewDelhi

[Dr Sreenidhi dhambolam @urolsreeni]

#Apollo11 #urology

[Dr Sreenidhi dhambolam @urolsreeni]

Fusicon 2024 Urology conference

[Dr Sreenidhi dhambolam @urolsreeni]

@usioffice @BAUSurology @AmerUrological @Uroweb @USANZUrology @SIU_urology @SGUrologia @sanjaybkulkarni @DrPNMaheshwari @pmulawkar @rbsabnis Rip sir