Behind the scenes in the lab 🔬: Dr. Arne Peirsman, one of our postdoctoral researchers under Dr. Vadim Jucaud, putting our new Leica STELLARIS 8 confocal microscope to work.
The STELLARIS 8 delivers higher sensitivity and spectral flexibility thanks to a tunable White Light Laser with 5 Power HyD detectors, which capture brighter signals with outstanding contrast and resolution. Dr. Peirsman is using the microscope’s multi-label imaging, that helps to separate signals, to localize different cell types and visualize perfusable microvasculature with greater fidelity within the fat tissueoid-on-a-chip. Always inspiring to see our researchers pushing innovation forward!
#TerasakiInstitute #LeicaSTELLARIS #BehindTheScenes
VJLabs @ Terasaki Institute awarded NIH R21 grant to advance xenotransplantation research using organ-on-a-chip technology, via @EurekAlert! @TerasakiInst https://t.co/iO2BCuGq7m
When exposed to allogeneic T cells, the LToC demonstrates clear, measurable features of immune‑mediated rejection, including endothelial damage, reduced liver markers, elevated HLA‑I expression, and a strong surge in inflammatory cytokines. These responses closely resemble patterns observed in clinical liver transplant rejection, offering researchers a real‑time view of how the immune system interacts with human liver tissue.
According to Principal Investigator Dr. Vadim Jucaud (@drjucaud), this platform has strong potential to improve immunosuppressive drug testing and support more personalized transplant strategies.
The work also continues the legacy of Dr. Paul Terasaki, advancing technologies designed to improve outcomes and quality of life for transplant patients
#TerasakiInstitute #LTOC #TransplantResearch
Join us Friday August 7th at 11 am PST for a fireside chat on:
Creating High Quality Schematics with PowerPoint
Register today. Spaces may be limited.
https://t.co/gTsEktKZ9M
#academia#design#schematics#science#create#aimbig…