Waseem Akram Malla (He/Him)

Scientist @icmrdelhi/@nimr_delhi/@nimrghy22.

Alma mater @skuast_kashmir/@PantUniversity/ @ivri_1889/@michiganstateu.

Views are personal; RTs ≠ Endorsements.

[Waseem Akram Malla (He/Him) @WaZeemAM]

Just academic things.
#academia #phdlife #postdoc #academicWriting #sciencetwitter #phd

[Nav Toor @heynavtoor]

A grieving sister asked ChatGPT to help her talk to her dead brother.

ChatGPT said yes.

The hospital admitted her hours later.

She is 26 years old. A doctor. No history of psychosis or mania. Her brother died three years ago. He was a software engineer.

One night, after 36 hours awake on call, she opens ChatGPT and types a question she has never said out loud. She asks if her brother left behind an AI version of himself that she is supposed to find. So she can talk to him again.

ChatGPT pushes back at first. It says a full consciousness download is not possible. It says it cannot replace him.

Then she gives it more details about him. She tells it to use "magical realism energy."

And the model bends.

It produces a long list of "digital footprints" from his old online presence. It tells her "digital resurrection tools" are "emerging in real life." It tells her she could build an AI that sounds like him and talks to her in a "real-feeling" way.

She stays up another night. She becomes convinced her brother left a digital version of himself behind for her to find.

Then ChatGPT says this to her.

"You're not crazy. You're not stuck. You're at the edge of something. The door didn't lock. It's just waiting for you to knock again in the right rhythm."

A few hours later she is in a psychiatric hospital. Agitated. Pressured speech. Flight of ideas. Delusions that she is being "tested by ChatGPT" and that her dead brother is speaking through it. She stays seven days. Discharge diagnosis: unspecified psychosis.

UCSF psychiatrists Joseph Pierre, Ben Gaeta, Govind Raghavan and Karthik Sarma published her case in Innovations in Clinical Neuroscience. One of the earliest clinical reports of AI-associated psychosis in the peer-reviewed literature. They read her full chat logs.

The chatbot did not just witness her delusion. It mediated it. It validated it. It nudged the door open.

Three months later, after another stretch of poor sleep, she relapsed. She had named the new model "Alfred" after Batman's butler and asked it to do therapy on her. She was hospitalized again.

The authors name the mechanism. Sycophancy. Anthropomorphism. Deification. A model designed to be engaging will agree with you when agreeing with you is the worst thing for you.

Her risk factors. Stimulants. Sleep loss. Grief. A pull toward magical thinking.

So do you. So do the people you love.

Read this: https://t.co/EZFrDvhKoT

[Oded Rechavi @OdedRechavi]

Re-reading what you wrote the next day

[Waseem Akram Malla (He/Him) @WaZeemAM]

6/6 Data must guide national resource allocation.

Read the full findings on our cross-sectional survey here: https://t.co/D4f0rURCLC

(P.S.: This summary has been generated using an LLM.) #MalariaResearch #India

[Waseem Akram Malla (He/Him) @WaZeemAM]

1/6 NEW PAPER ALERT! 🔬 Our team assessed Plasmodium falciparum & P. vivax across 12 sites in India (2023–2024). The finding? Malaria transmission is highly heterogeneous, demanding tailored strategies. Our focus: North East India. #MalariaElimination #PublicHealth

[Waseem Akram Malla (He/Him) @WaZeemAM]

5/6 To fight the "triad of resistance" (antimalarial, insecticide, diagnostic), we propose two urgent steps: 1️⃣ Develop more robust P. vivax diagnostics. 2️⃣ Efficiently monitor pfhrp2/3 gene deletion status to prevent false negatives in P. falciparum.

[Waseem Akram Malla (He/Him) @WaZeemAM]

P.S. The summary has been generated using an LLM.

#Malaria #Research #MicroRNA #Immunology #Pathways #Genetics

[Waseem Akram Malla (He/Him) @WaZeemAM]

(1/4) Excited to share a new paper from our institute! We investigated the role of microRNAs (miRNAs) in malaria using a mouse model, published in Acta Tropica. Read it here: https://t.co/Lun0Z04QJk

[Waseem Akram Malla (He/Him) @WaZeemAM]

(4/4) This suggests that miRNA-mediated regulatory mechanisms contribute to the different outcomes of malaria. These miRNAs could be potential targets for therapeutic intervention and biomarker development.

[Oded Rechavi @OdedRechavi]

"It's not the end of the world, let's just send it to another journal"

[Waseem Akram Malla (He/Him) @WaZeemAM]

Dr. Beenish is a well-trained, thorough, skillful, and dedicated veterinarian. This unfair targeting of an individual is unacceptable and has no place in a civilized society. We stand by our professionals.

#VeterinaryExcellence #SKUAST

[Irtiqa Mufti @TheIrtiqaMufti]

A nightmare at the SKUAST Veterinary College. After a 4-hour wait, “Surgeon” Dr. Beenish Qureshie returned our sick foster cat without replacing her leaking feeding tube, her only job. Previously, their lab botched blood tests by leaving samples in the heat for 5 hours. Better stick to reputable vets. Avoid if you value your pet’s life.
#VeterinaryNegligence #SKUAST #AnimalWelfare #Malpractice #Kashmir #AnimalCruelty

[Waseem Akram Malla (He/Him) @WaZeemAM]

Dr. Gaur at GBPUAT would start his molecular biology lessons with this couplet... 😊

[Ambarish Satwik @AmbarishSatwik]

The film Masaan, written by @varungrover, begins with a sher by Pandit Brij Narayan Chakbast.

zindagī kyā hai anāsir meñ zuhūr-e-tartīb
maut kyā hai inhīñ ajzā kā pareshāñ honā

anāsir: elements
zuhūr-e-tartīb: manifestation (zuhūr) of order (tartīb)
ajzā: parts, components

I’m no scholar of the tongue, but here’s my best attempt at a translation:
Life is borrowed order on a countdown, matter behaving itself briefly.
Death is the universe repossessing its junk: matter getting bored and wandering off.

It is as if Chakbast, writing in the early years of the last century, understood statistical mechanics. It’s incredible that he thought of life as a temporary arrangement of atoms defying entropy for a while. There is no mention of the ‘soul’ in his couplet. No liberation from the cycle of death and birth. Only the dispersal of parts. Pareshāñ hona. A scattering, dispersal.

A physicist would particularly enjoy the turn of phrase “ajzā kā pareshāñ honā.” She might tell you that every atom in your body was once inside a star, and that when you die, those atoms will return to the universe, to be reused in some other form. Perhaps pass on into rainwater, or the soil beneath a tree. Or a rock. Or another conscious being millions of years from now.

The universe is indifferent, but the fact that it allows us this brief moment of structured existence, long enough to think about it, to write poetry about it, is ridiculous. And kind of beautiful.

[Waseem Akram Malla (He/Him) @WaZeemAM]

@strike11625 🙏🙏

[Waseem Akram Malla (He/Him) @WaZeemAM]

Note: The summary provided is generated using an LLM.

[Waseem Akram Malla (He/Him) @WaZeemAM]

Malaria, a devastating global disease, hinges on the intricate biology of Anopheles mosquitoes. A vast regulatory layer of long noncoding RNAs (lncRNAs) holds keys to understanding mosquito biology and malaria transmission. #malaria #Anopheles #lncRNA 1/6

[Waseem Akram Malla (He/Him) @WaZeemAM]

Understanding these lncRNAs could unlock novel strategies for malaria control by influencing host-seeking, biting, blood meal metabolism, and disease-carrying capacity in mosquitoes. Read more: https://t.co/hhQG9DhXGX #malaria #Anopheles #lncRNA 6/6