Our creation of 'ligand-operable cages' -- designed protein cages that disassemble when they bind a specific cellular protein -- has been published: https://t.co/4tN8uJWRVZ
I'm thrilled to share our latest work on designing imaging scaffolds to determine the structure of small proteins using cryo-EM!
https://t.co/FbXdjnABxG
‘Rigidified Scaffolds for 3-Angstrom Resolution Cryo-EM of Small Therapeutic Protein Targets’
Congrats @rcastellsg@kylemeador and team!
With our imaging scaffolds, we report a 2.9A structure for a ~19 kDa KRAS protein oncogenic mutant.
https://t.co/4SkwhwkbxP