Zzznorks

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[Maria Marinova, PhD @m__marinova]

New Yamanaka preprint suggests rejuvenation by partial reprogramming must be optimized one cell lineage at a time. They investigate the key question of whether cells can become biologically younger, then recover their identity and function, while still maintaining the rejuvenation effect.

After the reprogramming was done, 3 human cell types took on quite different trajectories:

-Endothelial cells recovered their identity, retained a younger DNA methylation age and improved vascular function.
-T cells recovered only after shallow reprogramming but showed enhanced effector function.
-Fibroblasts retained a younger DNA methylation age but did not fully recover their proliferative capacity.

The authors' conclusion: "Partial reprogramming involves a lineage-specific tradeoff between rejuvenation and recovery that must be optimized one lineage at a time."

https://t.co/bHNqtjsUhY

[Trolling.Canuck @TrollingCanuck]

🎯

[Dr Singularity @Dr_Singularity]

We live in an age of miracles.

Scientists at Germany’s University of Bonn have developed a method to gradually reverse aging markers in human cells by up to 60 years in less than 2 months.

The breakthrough allows researchers to track the rejuvenation process step by step, potentially helping unlock safer, more effective aging reversal therapies.

The results are currently limited to laboratory grown cells.

2030s - age reversal tech in coming

[Toby Rogers @uTobian]

The @nvidia board of directors wiped out one trillion dollars in shareholder value. They should all be replaced by people who actually know what they are doing.

[Wall Street Mav @WallStreetMav]

The German government has made conditions so horrible in Germany that Mercedes has halted all future investment in their home country. They are planning to shut plants and relocate jobs.

Energy costs are too high and unions are impossible to work with. The cost of an hour of labor in Germany is 5 times higher than locations in eastern Europe.

[Gen Z Anxiety 🫪 @Genz_anxiety]

🚨 JUST IN: Billionaire Nvidia shareholder Leo KoGuan says he won’t invest more in the company without Jensen Huang 💰🇺🇸

@grok please verify.

[Global Dissident @GlobalDiss]

🚨🇵🇱 Polish President Nawrocki BLOCKS the EU's internet CENSORSHIP.

He vetoed implementing if the Digital Services Act, warning it would hand the government "arbitrary control" over what people can publish online.

A major VICTORY against Brussels' GRIP on free speech!

[Simon Betschinger @SBetschinger]

Wir NVIDIA-Aktionäre sollten uns verbünden und den NVIDIA-Verwaltungsrat neu besetzen.

Dank Jensen Huang sind rund 27.000 NVIDIA-Mitarbeiter durch Mitarbeiterbeteiligungsprogramme zu Millionären geworden.

Jensen Huang hat den Wert der NVIDIA-Aktie um 70.000 % gesteigert.

Der NVIDIA-Verwaltungsrat handelt kleingeistig und weder im Interesse der Eigentümer noch im Interesse der Mitarbeiter.

Moralische Schuld hat Jensen Huang gegenüber seiner Ehefrau. Wenn sie ihn vor die Tür setzt und mit 70 Mrd. USD aus der Scheidung hervorgeht, ist das eine ausreichende Strafe für seine Fehltritte.

Als NVIDIA-Aktionär fordere ich, den NVIDIA-Verwaltungsrat zu feuern und jeden Huang zurückzuholen.

[Preston Byrne @prestonjbyrne]

Australia's "eSafety" commissioner has sent several of my U.S. clients demands which, if sent by the U.S. government, would be unconstitutional.

Australians: everything that "eSafety" does, from an American POV, is censorship.

We don't tolerate it. Neither should you.

[范凯说AI @fankaishuoai]

如果黄仁勋被 fire，英伟达的价值至少腰斩，根本不值得继续持有了。

不要去看英伟达现在的 Forward PE 很低，这个没意义。

英伟达自己不生产芯片，不生产服务器机架，英伟达本质上就是一家芯片设计公司。

没有黄仁勋的行业前瞻性，对台湾韩国芯片的内存制造行业的影响力和整合能力，没有黄仁勋对各个 Cloud 厂商的影响力和整合能力，没有黄仁勋积极的跑大客户，甚至各个国家去社交 BD，

一家芯片设计公司凭什么成为全球股王，凭什么常年 70% 以上的利润率？

没有黄仁勋，���能保证那些供应商和客户还那么配合吗？

[🇨🇳 Guo Shen 郭深 @GuoShenCN7]

他们没有“解雇”黄仁勋（Jensen Huang），而是将他彻底抹去了。

他花了33年时间打造英伟达（Nvidia），却在4天内化为乌有。

在我看来，事情的真相是这样的：

黄仁勋的影响力变得太大了。英伟达是整场人工智能（AI）竞赛的引擎，而他正处于这一切的核心——谁能拿到芯片？能拿到多少？AI的下一阶段发展速度有多快？这些都由他说了算。

而他背后的那些人——那些习惯了发号施令、掌控巨额资本的势力——发现他们已经无法控制他了。

他不再听从他们的指令。

他们强推自己的计划，他拒绝了；他们再次施压，他依然坚持按自己的方式推进。

你没法直接解雇这样一个人，否则股价会崩盘，全世界也会追问原因。所以，他们采取了另一种手段。

他们把他塑造成了一个“反派”。

看看时间线：

→ 11月8日：他承认了一段私情。

→ 几天后，各大媒体的头条都称其涉及“中国间谍”。

→ 新加坡方面表示，他们针对该女性的调查与“间谍活动”无关——但几乎没有媒体报道这一点。

→ 今天：他不再担任首席执行官（CEO）、总裁及董事会成员，即刻生效。

→ 同一天，英伟达迎来了史上首位董事长（Chair）。

一段私情不可能在4天内终结一位深耕33年的创始人的职业生涯。

这分明是一场精心策划的“抹黑行动”。

同样的措辞，同样的反派人设，在同一周内，铺天盖地而来。

这根本不是新闻，而是一场针对他个人声誉的蓄意打击。

至于事件核心的那位女性？据彭博社报道，她已经身在北京。这意味着她无法接受质询，而黄仁勋也永远无法彻底洗清自己的名声。这件事将永远悬而未决——这简直是完美的“武器”。

就连特朗普都曾称他为“体面人”，但这毫无作用。

这从来就不是关于一段私情的问题，而是关于谁能掌控那些驱动AI的芯片。在AI发展的下一阶段，他们需要一个“听话”的人。

那么，看看现在坐在他位置上的人是谁：首席财务官（CFO）科莱特·克雷斯（Colette Kress）出任“临时”CEO。而且，英伟达历史上首次设立了董事长一职，凌��于CEO之上。

她并非在真正掌管英伟达，她不过是个傀儡。这一切的幕后推手，直指那些一心想让詹森（Jensen）出局的人。

本周，大多数人看到的会是一桩性丑闻；但几年后，他们终将看清这背后的真相。

他们或许能让詹森的名字淹没在新闻头条里，却无法将其从历史中抹去。关注我，并将此文转发给那些依然轻信新闻头条的人。

[Carlo @carloAI]

nvidia board should be fired just for considering firing jensen

[Null @Vhoyde]

Nvidia replaced an engineer with an accountant. Guess we know what happens next

[紫水晶Amethyst @jjamesw1]

绝大多数人对黄仁勋在英伟达作用的认识还是太幼稚了。
美国那套空降兵制度（职业经理人制度），
根本不可能玩转这种高科技企业。

加拿大北电危机了，叫来一个经理人，结果北电不存在了。
黑莓危机了，叫来一个经理人，谁还知道黑莓啊。
诺基亚危机了，叫来一个经理人，诺基亚手机很快就消失了。
这种例子数不胜数。

苏妈管不了英伟达，库克管不了英伟达。
英伟达42000人，单人利润286万美元，是苹果的四倍多。
这些都是老黄的高效管理模式导致的。

[Brivael Le Pogam @brivael]

NVIDIA employees: go on strike. Now.

Not for a raise. Not for more PTO. For your founder.

Jensen Huang was just pushed out in four days, after thirty-three years building the company. The GPU, CUDA, the entire infrastructure the world's AI runs on today. And it ends with a three-line press release on a Thursday morning.

Here are the facts. Sunday, Huang admits to an affair and apologizes to his teams. The board launches an independent investigation, led by Wachtell Lipton and a former federal prosecutor. Thursday, he resigns under pressure. The investigation hasn't reached any conclusion. No technology leak has been established. No misconduct has been announced.

The sentence came before the verdict.

Let me be clear: if the investigation shows that NVIDIA secrets ended up in Beijing, he has to go, and nobody will defend him. But you don't unplug the most important builder of the decade over press reports and a market panic. It's called the presumption of innocence. It applies to founders too.

And it has worked before.

November 2023. OpenAI's board fires Sam Altman on a Friday night. Within days, more than 700 of roughly 770 employees sign a letter: bring Altman back, or we all walk. Five days later, Altman is back, and most of the board that fired him is gone.

Call it the Altman precedent: in a company built on talent, real power doesn't sit with the board. It sits with the people who build.

NVIDIA's engineers hold that power today. They're the ones running the machine. Without them, there is no next generation of chips.

So put down your tools. All of you. And tell the board: no successor until the investigation is done. Facts first, sentence second.

A founder isn't an executive you swap out. A founder is the soul of the company. Apple learned that when it pushed out Steve Jobs in 1985. It took twelve years and a near-bankruptcy to bring him back.

NVIDIA doesn't have twelve years. The AI race won't wait for anyone.

A company's soul isn't something you vote on in a boardroom. It's something you fight for.

[Europoor @theEuropoor]

European innovation is finding new ways to tax the same €20

[Lukasz Olejnik @lukOlejnik]

The European Commission is ordering Google to share the search data of all Europeans with other companies (AI chatbot makers, search engines, etc.), after a kind of "anonymisation". I tested it on the real Google data, hundreds of billions of search records. I broke it.

Findings. I singled out the people behind half a million searches, and that only for few countries over one month of August (record isolation). I joined the pieces of search history beyond the defined cap of 3, more than 200,000 sets just for Germany and only in August (linkage). I also confirm that it is possible to perform inference on the dataset, for example concerning health, religion or political opinions. This moves us beyond data protection, and in the national security direction.

My report: "Alone among a thousand". (link below)

[Beff (e/acc) @beffjezos]

This was always the plan of the Dems btw.

You're seeing the shift now. They want to monopolize superintelligence and achieve reg capture with a few insiders.

[Laurent Michelon @LAURENTMICHEL0N]

The world must take notice, because this developemnt of the Jensen Huang saga is extremely grave.

The Economist is not only taking sides, based on G.d-knows-what authority, but it is now applying to international business and politics the trick played by Western media at the national level against people they want to see gone : the role of the Prosecutor, who condemns before the investigation, before any trial.

Even before justice by trial, there is in Western countries a travesty of justice which one could call "trial by media".
The media frames a story a certain way, massages it into the public opinion, which will in turn give pressure to the justice system.

“Public opinion has spoken; now the courts must follow”.

This is an attempt at public crucifixion, by forcing the authorities to yield to public pressure rather than legal evidence.

[Kieler Aktionär @KielerFinanzen]

52 % Staatsquote heißt in erster Linie, allen jungen Menschen die Zukunft zu versauen.

Und zwar nachhaltig.