In this study, we reveal that type II interferon signaling following immunotherapy drives the generation of an aged, high PD-L1 expression immunosuppressive neutrophil population. This provides new insights into how to enhance the efficacy of immunotherapies in the future.
Thrilled to share our latest work on the role of neutrophils in immunotherapy, now out in @ImmunityCP ! π₯³ A huge thank you to all our amazing collaborators for their invaluable support! π€ @soehnleinlab @jeffreyravetch
Thrilled to share our latest work on the role of neutrophils in immunotherapy, now out in @ImmunityCP ! π₯³ A huge thank you to all our amazing collaborators for their invaluable support! π€ @soehnleinlab @jeffreyravetch
IFN-Ξ³ produced during immunotherapy induces PD-L1 expression by neutrophils with an aged phenotype that drives therapy resistance @ImmunityCP@0310Polo@karolinskainst
https://t.co/V2l6hJrvvg
Great thanks to Oliver @soehnleinlab and all local organizers @CRC_TRR332 for such a great meeting! It means a lot to the young participants like me that we could talk to and learn from the senior scientists in this field! Hope we could meet again soon! @neutrophil2024
Very happy our unexpected findings about CAFs were finally published on CMI as a correspondence. Please check it out if you are interested in CD1d biology in cancer: https://t.co/XQc4Gvypnx