New paper with @skleinstein and @28Cole on how to build B cell lineage trees with paired heavy and light chain BCRs with Dowser! Paired H+L improved accuracy, but *most* methods highly biased when mixing #SingleCell and bulk #BCR (1/3). https://t.co/m7a54fyAcv
You can now build B cell trees using paired heavy and light chains with Dowser! We show adding light chains significantly improves tree building across methods. Mixing bulk and single cell can cause significant biases, but these are fixed with multi-partition models. @skleinstein
Your Earth Day reminder that we must not go back to normal after this crisis ends.
We should not try to prop up oil prices. We should not bail out oil companies. We should accelerate our shift to solar, wind, and other non-fossil fuels.
Second US case of #nCoV2019, also due to travel to Wuhan. Sixty-three others under investigation nationally (I think it likely that most of those will be negative). https://t.co/VqTSGyFb3n
Of all the aspects of the rapidly spreading Wuhan virus, this is perhaps the most alarming: A single patient has infected 14 health care workers.
That's what's called a "super spreader" -- and identifying them is a key element of fighting the virus. https://t.co/oMdpe4FO45