Today is a historic day. India has entered 2nd stage of our three stage nuclear power program with the achievement of clriticality of PFBR. Congratulations to every contributor to this critical technology that makes India only the second country to operate a large fast reactor.
@DalrympleWill@mukulkesavan Doesnt it follow that a state that is violent on its own majority does not have a right to exist? Would you make this argument against Iran or Syria (Assad days) or Taliban’s afganistan or even China? You may want a regime change in Israel but to say it has lost the right to be??
ok so the rosie story was even more insane than it looked
> be the australian tech guy who made a cancer vaccine for his dog
> first try: genetic algorithms to design a new drug from scratch
> works in simulation but would take years to test
> second try: screen 1 million existing compounds against the mutation
> two weeks of computation. find a perfect match
> it's patented
> patent holder says no to compassionate use
> what_did_you_expect.jpg
> spend two weeks just being with the dog
> 2am idea: what if i just make a vaccine
> chatgpt for pipeline, gemini for construct, grok for validation
> 300 gigabytes of raw sequencing data to half a page of vaccine construct
> university ethics approval would take until mid-2026
> dog doesn't have that long
> panik
> canine cancer expert connects him to a lab in queensland with existing approval
> drive 14 hours to get there
> inject
> three weeks later the tumors swell. immune system swarming
> six weeks later shrinking
> two months later legs returning to normal
> one mass doesn't respond
> sequence it again
> different cancer. the vaccine worked. the body grew a new tumor
he's now building a company so every dog owner can do this
he had the technology the whole time. he spent 18 months fighting for permission to use it
@jasonwilliamsmd The time from scan to biopsy to surgery to chemo/meds so critical. There is some complacency in early stage BC, the patients not as prioritised in public health systems
Wishing Susie Wiles a full recovery. Early-stage breast cancer caught early has excellent outcomes, and the decision to act immediately is smart.
One thing most patients aren't told is that the clock starts ticking the moment a biopsy is performed. A 2023 study in Cell Reports Medicine looked at over 176,000 early-stage breast cancer patients and found mortality risk rises significantly when treatment is delayed beyond 53 days after biopsy. The reason is biological. The biopsy creates a wound inside the tumor, and that wound environment becomes dominated by M2 macrophages that promote angiogenesis and help cancer cells gain the ability to spread. You've essentially disturbed a hornet's nest and then walked away.
That same study showed that NSAIDs like ketorolac given at the time of biopsy can disrupt this process by blocking the COX-2/PGE2/EP2 loop that drives those pro-metastatic changes. A study in the British Journal of Anaesthesia found ketorolac or diclofenac at the time of breast cancer surgery reduced recurrence or metastasis risk by 6%. With 40,000 women dying from breast cancer each year in the US, that's a meaningful number of lives from something as simple as an anti-inflammatory.
Something else worth considering is that early-stage breast cancer does not have to mean losing a breast. At Williams Cancer Institute, our breast cancer patients keep their breasts. Cryoablation and intratumoral immunotherapy treat the tumor directly, at the time of biopsy, while preserving the breast entirely. No mastectomy. No reconstruction with a foreign body that creates a new wound environment for cancer to exploit. The physical and emotional toll of losing a breast is real, and the stress response from major surgery suppresses the immune system for months. Keeping a woman whole matters for her healing in every sense.
We can do better than the conventional sequence of biopsy, wait, surgery, wait, chemo, wait. The needle is already in the tumor. That's the moment to start.
25 years ago at Eden Gardens Rahul and I shared a partnership that will forever remain special. In a moment when the game looked beyond us we chose belief, patience and resilience. That stand was not just about runs but was about trust, teamwork and fighting for every session. Grateful to have shared that journey with Rahul and to be part of a Test that reminded us all that in cricket comebacks are always possible👍 @BCCI #PowerOfPartnership #Believe #Resilience
@IterIntellectus Hi mate, there are a few people here claiming this is fake news. Rose and I were on Aussie national television this morning:
https://t.co/2ruE3LR4Wx
.@GemsOfBollywood has formally filed complaint with @KanoongoPriyank about sexualised portrayal of girls in school uniforms in popular music videos and entertainment content and asked for urgent advisory and warnings
His work in protecting minors from criminal and perverted rackets is simply remarkable
Today’s to think of anyone else who has acted in these issued with such consistency and determination
We have raised, among others, these concerns:
- Sexualises imagery associated with minors, eroded the dignity of girl child
- Normalises adult sexual attraction towards schoolgirls
- Conditions young audiences, particularly boys and teens, to associate schoolgirls with sexual desirability
- Undermines the spirit and intent of child protection laws
Every few months, I write an updated, idiosyncratic guide on which AIs to use right now.
My new version has the most changes ever, since AI is no longer just about chatbots. To use AI you need to understand how to think about models, apps, and harnesses. https://t.co/m6iTbqsdbK