Anxhela Docaj

Biomedical Engineering PhD student at @CityCollegeNY
Research Lab: Carriero Lab - Multiscale Biomechanics and Mechanoadaptation

[Prof Natalie A Sims @NatalieASims]

All welcome to join us for a virtual seminar from the quite wonderful @JoyYWu next week on the intersections of 🦴and🩸@ANZBMSoc @ANZBMS_ECIC I’m really looking forward to hearing her latest work!

[James Iatridis @iatridislab]

⁦⁦⁦⁦⁦@ORSsociety⁩ ⁦@cpane94⁩ @pcz_2016 @ad_425 #orsambassador scavenger hunt….in progress!

[Prof Natalie A Sims @NatalieASims]

Thread: Thanks to @ECTS_science for inviting me to speak today on What is New in Basic Bone Biology Techniques at #ECTS2021. It is an overview of many interesting papers over the past 18 months, so to make it simple for listeners, here’s a thread of the papers I’ll discuss. 1/21

[James Iatridis @iatridislab]

⁦@ORSsociety⁩ ⁦@cpane94⁩ #orsambassador scavenger hunt event… team Partridge Family staging Abbey Road picture at HSS with @PCZ_2016 ⁦@425_ad⁩ and Nicola Partridge. Super fun event and great to see NYC ORS members!

[Anxhela Docaj @425_ad]

Diabetic patients can always try to manage the condition on their own through lifestyle and home remedies. Committing to managing your diabetes, scheduling a physical exam and regular eye exams, etc. Mayo Clinic has all these tips and much more https://t.co/1QoVBPtcVw

[Anxhela Docaj @425_ad]

The outcome was that not only A1C levels had decreased but also patients had lost weight with both kinds of drugs. The results are promising, however SGLT-2s have not been approved by the FDA yet. There are concerns relating to diabetic ketoacidosis https://t.co/yyKMyx4P8u

[Anxhela Docaj @425_ad]

Insulin isophane is an intermediate acting insulin used to treat blood sugar level in adults and children. Depending on what other medicines that you may be taking, this insulin may not work. Its side effects may be weight gain, swelling, itching, etc. https://t.co/IqRKnaDFpH

[Anxhela Docaj @425_ad]

In two studies involving adults with type 1 diabetes, the addition of two different oral type 2 meds from the SGLT-2 inhibitor class lowered A1C without causing hypoglycemia. Other researchers added injections of a type 2 drug from the GLP-1 receptor. https://t.co/yyKMyx4P8u

[Anxhela Docaj @425_ad]

https://t.co/ncBhODLkbV

[Anxhela Docaj @425_ad]

Blood Glucose readings may vary considerably, the target A1C is most likely lower. A person without diabetes stays within a narrow band, ranging from about 70 to 130 mg/dl. The person with type 1 diabetes,oscillates widely between low and high depending on insulin/food intake.

[Anxhela Docaj @425_ad]

Insulin detemir, also known as Levemir, is a long-acting sterile solution. It is recommended for once- or twice-daily subcutaneous administration. Some common side effects with other insulins are hypoglycemia, hypersensitive and allergic reactions.
https://t.co/w3ir6KSxQm

[Anxhela Docaj @425_ad]

It is important to keep blood glucose levels targeted for preventing diabetes-related complications and may also help prevent dementia later in life. Studies compared patients with diabetes or not that later on developed dementia or did not. https://t.co/YUC6twBjfr

[Anxhela Docaj @425_ad]

Another insulin to treat type 2 diabetes is Lantus. It is a sterile solution consisting of insulin glargine dissolved in a clear aqueous fluid, where each milliliter of lantus contains 100 Units insulin glargine. https://t.co/CvmhEYPZKj

[Anxhela Docaj @425_ad]

A1C test is a clinical tool that experts now recommend using it to diagnose diabetes and prediabetes. An A1C of below 5.7% is considered normal, while A1C levels of 6.5% and above call for a diagnosis of diabetes. Anything in between links to prediabetes. https://t.co/7NxI8W20Xk

[Anxhela Docaj @425_ad]

Insulin aspart injuction is also known as Novolog, a fast-acting insulin. It is produced by recombinant DNA technology utilizing Saccharomyces cerevisiae. Its side effects can be hypoglycemia, allergic reactions, and hypokalemia. https://t.co/DSKKMB9P0r

[Anxhela Docaj @425_ad]

A1C molecule is hemoglobin A— it has the same sequence of amino acids—but with one critical difference: a glucose molecule stuck to one end. This could be the reason why hemoglobin A1C tracked with blood glucose levels is higher in people with diabetes. https://t.co/7NxI8W20Xk

[Anxhela Docaj @425_ad]

Another type of insulin to treat type 2 diabetes is Humalog. It is also known as insupin lispro. Different from human insulin, humalog has lysine and proline. Some side effects are: lipodystrophy, weight gain, peripheral edema, ect.
https://t.co/isuWPSIYbt

[Anxhela Docaj @425_ad]

https://t.co/LV4lpWxjmG

[Anxhela Docaj @425_ad]

For some patients gene therapy for neuropathy relief seems to have successful outcomes. The gene was injected in each leg twice two weeks apart. Some patients had pain relief and the therapy seemed to work very well for them.

[Anxhela Docaj @425_ad]

Diabetic patients sometimes suffer diabetic neuropathy as well, a tingling sensation, pain or numbness in their feet. Scientists discovered that intensive blood glucose management does prevent amputations but unfortunately, not foot ulcers. https://t.co/1fkYJD7Cdl