AV Washington

Dr. Washington’s lab studies the #TLT-1 #platelet receptor which influences #hemostasis and inflammation mediated by platelets and the immune system.

[AV Washington @AVWashingtonLab]

A special opportunity at #ISTH2025 to celebrate the power of scientific lineage - introducing Dan McViker to his “scientific grandchildren” in platelet research. Science is as much about innovation as it is about connection — across generations, disciplines, and borders.

[AV Washington @AVWashingtonLab]

Still in Kraków, presenting at the GENOMICA Student Conference of Genetics. A vibrant community of undergraduate & graduate researchers. I was truly impressed by quality of their work, especially the posters—hearing students explain their work was energizing.

[AV Washington @AVWashingtonLab]

Today in Kraków, I shared a proposed mechanism of TLT-1 function linking in vitro findings with in vivo data at Instytut Farmakologii im. Jerzego Maja, Polish Academy of Science. Excited about the potential for collaborations ahead.
#ScienceCollaboration #TLT1

[AV Washington @AVWashingtonLab]

Thankful for the opportunity to present at the at #HTRS2025 this week on how TLT-1 nucleates clot formation in the presence of low levels of #platelet agonist. This mechanism could open new avenues for therapeutic strategies in coagulation disorders.

[AV Washington @AVWashingtonLab]

Shade Onunkun, Nana Boateng & Dr. Lauver from MSU Department of Pharmacology & Toxicology joined Dr. Avery’s graduate seminar at @oaklandu to present their latest research findings. Great presentations, sparking insightful discussions and fostering collaboration!

[AV Washington @AVWashingtonLab]

The OU @oaklandu University Career & Life Design Center & Biojourneys initiative teamed up with Endo Pharmaceuticals to help students explore their personalized career pathways! Glad to be part of this collaboration that empowers students to discover their unique strengths.

[AV Washington @AVWashingtonLab]

I recently had the opportunity to speak at the @oaklandu Undergraduate Research Society, sharing insights and experiences with students and researchers. It was an honor to contribute to the discussions and engage with emerging scholars.

[AV Washington @AVWashingtonLab]

Congratulations to Madison Luxmore and Prisha Mehta, undergraduate students at #AVWashingtonLab, for outstanding poster presentations at the Midwest Platelet Conference in KY! Always inspiring to see young researchers presenting complex concepts and engaging discussions.

[AV Washington @AVWashingtonLab]

Exciting News! Welcoming Dr. @SravyaNimmala to our lab! 🌟 A physician with hands-on clinical experience, she’s now pursuing a Ph.D. in medical research to address critical gaps in healthcare.
Connect with her to discuss #Hematology #Research

[AV Washington @AVWashingtonLab]

An incredible milestone! Huge congratulations @SiobhanBranfie1 Ph.D. for completing her academic journey at @oaklandu Watching her pour her heart into this journey was inspiring. She’s lifted the laboratory to new heights. Hope to remain part of this incredible journey.

[AV Washington @AVWashingtonLab]

Great summary of the signaling pathways involving regulation of #platelet ROS production and their role in platelet function and thrombosis.

[JTH @JTHjournal]

#Platelets are players #cardiovascular diseases such as atherosclerosis and venous #thrombosis.

Reactive oxygen species (ROS) are generated within activated platelets.

Read new review now!

https://t.co/bhOzhz68Km

[AV Washington @AVWashingtonLab]

Recently a colleague and I presented an action plan for inclusive teaching, marking the culmination of an incredibly valuable learning journey at @CETLatOU. Inclusive teaching is a commitment to ensuring that every student feels valued, respected & empowered to succeed.

[AV Washington @AVWashingtonLab]

Our new publication @of_therapeutic TLT-1 plays a pivotal role by binding fibrinogen. Our assay identified 80 potent inhibitors to significantly reduce TLT-1 binding (80%) Promising avenue to combat thrombosis associated with cardiovascular disease. https://t.co/d4j1Dl0sNv

[AV Washington @AVWashingtonLab]

Implications of this study: platelets may prevent the exacerbation of ferroptosis-associated diseases dependent on CLEC-2;
platelets bind different types of iron substances ➡️platelets may play a significant role in the regulation of pathophysiological iron homeostasis.

[JTH @JTHjournal]

Ferric chloride activates platelets through CLEC-2. Tsukiji et al find platelet CLEC-2 attenuates ferric chloride-induced endothelial ferroptosis.
@clinlab_yama
https://t.co/CaqMc3dcEK

[AV Washington @AVWashingtonLab]

Washington Lab spotlight: Yashieta immerses herself in the world of hematology, where she develops skills in cryosectioning, tissue analysis, and genotyping. Stay tuned as Yashieta continues to make strides in her research journey! 🧬💡

#Science #Research #Hematology #TLT1

[AV Washington @AVWashingtonLab]

Inspiring career development discussion with young scientists of the Biomedical Research for University Students in Health Sciences Summer Research Prgm @michiganstateu!🌟It was energizing to engage with such articulate UG & veterinary students. They will do great things!

[AV Washington @AVWashingtonLab]

Excited to announce our latest from #AVWashingtonLab a new protocol for murine whole blood aggregometry as an alternative to traditional light transmission aggregometry https://t.co/fYDcSyy9O5 @SiobhanBranfie1 @Curr_Protocols @WileyGlobal

[AV Washington @AVWashingtonLab]

Actin filaments reside within human platelet microtubules ➡️ stress placed upon the microtubule network during motor-driven microtubule looping & sliding may facilitate the incorporation of actin into microtubules.

[Mark Dodding @MarkDodding]

Our latest paper on actin within platelet microtubules led by @ChisatoTsuji is now in print. https://t.co/3fwNOoo9Aa
Where else might those little turduckens 🦃🦆 be hiding? @BristolBiochem @UoBrisPPN

[AV Washington @AVWashingtonLab]

New potential therapy for breast cancer involving #platelets from @BloodJournal. “Targeting this irregular multicellular interplay may represent a novel immunotherapeutic strategy for TNBC without the adverse effects of systemic IC inhibition”

[Blood Journals Portfolio @BloodPortfolio]

Procoagulant platelets use these IC molecules to misguide immune cell responses, thus promoting tumor progression. https://t.co/N3VOpACImO #plateletsandthrombopoiesis #immunobiologyandimmunotherapy

[AV Washington @AVWashingtonLab]

BDUC (bleeding disorder of unknown cause ) patients show reduced platelet adhesion/ thrombus formation.➡️ To diagnose BDUC, platelet light transmission aggregometry should be performed as a minimum assessment. Platelet transfusions can be a potential treatment option.

[JTH @JTHjournal]

On #Cover #July
New @isth SSC paper on bleeding disorders of unknown cause
@MahaOthman8 @nikmutch @@Mtl_PlateletLab
https://t.co/Ii8d4MKjM2