Adi Doron

[Eran Malach @EranMalach]

My new paper is on arxiv, so I guess it now deserves a thread…

Let’s start from the end: AGI is possible (!) using… LINEAR next-token predictors!

How can this be? And what does this tell us about the power of next-token predictors?

https://t.co/3daDzvW2WF

1/n

[Lyda Hill Department of Bioinformatics @LHBioinf_UTSW]

Join us and @UTSWBrain as we host our next #NeuroChat on 12/8, 11a GMT-5!
Speaker: @AdiDoron, #GradStudent from @ELSCbrain
Abstract: https://t.co/vOoZBpppw5
#Astrocytes #RewardPathways #Hippocampus #NeuroInformatics #Bioinformatics #ComputationalBiology

[Adi Doron @AdiDoron]

@IM_Inman Indeed, the revolution is coming 😊

[Adi Doron @AdiDoron]

@BeetzJerome Thanks 😊

[Adi Doron @AdiDoron]

@mazefire56 @nbcsnl We were also surprised 😊

[Adi Doron @AdiDoron]

@neurokev Astrocytes are definitely the new stars 😊

[Adi Doron @AdiDoron]

@lisa_giocomo Thank you so much!

[Adi Doron @AdiDoron]

@BDehbozorgi83 @Nature Thank you!

[Adi Doron @AdiDoron]

Our paper is now out in @Nature!
https://t.co/a645FvCEOk
What started as a small side project ended up revealing new surprising capabilities of astrocytes - We chronically imaged hippocampal astrocytes and show that they encode reward location.

[Adi Doron @AdiDoron]

@PhilippMarkolin @Nature Thanks, we’re also excited about this 😊

[Adi Doron @AdiDoron]

@annmclemens @Nature Thanks!

[Adi Doron @AdiDoron]

@Sophistarete @Nature Indeed, the astrocytes are probably affected by, as well as affecting, the neurons nearby though we didn’t test this in this study. Manipulating the astrocytes could definitely be interesting.

[Adi Doron @AdiDoron]

@omerxsharon @Nature Thanks 😊

[Adi Doron @AdiDoron]

@hugospiers @Nature Thank you!

[Adi Doron @AdiDoron]

@kamsehrawat @Nature Thanks Kamini!

[Adi Doron @AdiDoron]

@hugospiers @RamosNeuro @ElDuvelle @vineettiruvadi @Nature @NeuroCellPress @NilsNyberg_ @caswellcaswell That’s a great paper that we sadly had to leave out due to the journal limitations, along with other relevant papers

[Adi Doron @AdiDoron]

@RamosNeuro @ElDuvelle @vineettiruvadi @Nature encoding scheme that we can see in the population ramping activity.

[Adi Doron @AdiDoron]

@RamosNeuro @ElDuvelle @vineettiruvadi @Nature Astrocytes are definitely not working in a vacuum, and are probably responding to neuronal activity as well as affecting neurons, though we did not test this in our study. The temporal dynamics of the astrocytic signal is different from the neuronal signal, leading to a different

[Inbal Goshen @GoshenInbal]

Our lab has a Nature paper!
A truly amazing work by @AdiDoron, showing that Hippocampal Astrocytes Encode Reward Location. You read correctly, astrocytes!
We oddly enjoyed the review process! Had sensible reviewers that helped us make the article better!
https://t.co/h51lVaHZga

[Adi Doron @AdiDoron]

Of course, this work couldn’t have been done without the help of the amazing Goshen lab members, as well as Alon Rubin and Yaniv Ziv. @GoshenInbal @ELSCbrain

[Adi Doron @AdiDoron]

As mice approach the reward location in familiar environments, astrocytic activity gradually increases. We do not see this ramping in novel environments nor when the reward is shifted in a familiar environment.