#STROKE🧵This topical review by Ballout et al. outlines the existing gap between histopathological studies and clinical trials that have shaped our understanding of current imaging constructs. #AHAJournals@AhmadBalloutMD@dliebesk@TudorGJovin
A Libertarian Textbook Case of Compassion and Collaboration.
Christians & Sunnis have welcomed Shiites seeking refuge. Greek Orthodox, Maronite, & Catholic schools have housed displaced families.
"Nevertheless, continued efforts to narrow the imaging-neuropathological gap are critical to ensure that our diagnostics keep up with our therapeutics, in that our imaging constructs evolve and remain in stride with our reperfusion therapies."
https://t.co/IsiUx41mqW
@TudorGJovin@dliebesk
"Our current imaging constructs have been critical in guiding us toward the forest but may have blurred the diversity of trees...
"This journey must also be met with a psychological shift, as we must reconcile our desires for precision with the exquisite time dependence of treatment and the immense difficulty in predicting the behavior of complex biological processes....
In the recent large core trials, the treatment effect of mechanical thrombectomy persisted across all imaging strata.
So, does core volume still matter?
Ongoing meta-analyses will be critical in defining this relationship.
Thoughts below 👇
https://t.co/88Mfb4Nwtn
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✋The degree of stenosis is not the whole story!
Why is it that some patients with ICAD are a higher risk of recurrent strokes than others?🤔
Enter Computational Fluid Dynamics (CFD)!
@ShadiYaghi2 I like it. Rather than $$$, maybe reviewer gets credits that can be used to support open access publication fees for future paper submissions to any journal that falls under the publishers umbrella.
@stephanamayer The recent LASTE study showed benefit of MT in patients presenting within 12 hours, with more than half of the patients having ASPECTS 0-2 and no heterogeneity of treatment effect across ASPECTS. So, probably, in most.
@MicieliA_MD@stephanamayer Great example, highlights the uncertainty I've had w/ several recent cases. At what shade of grey do we call this a "completed infarction". While there is a linear correlation b/w degree hypodensity & ionic edema, does this necessarily correlate w/ degree infarction?