Al Charest Lab

We Integrate Brain Cancer Biology, Signaling Networks and Tumor Immunology

- Cancer Research Institute, Beth Israel Deaconess Medical Center

[Oded Rechavi @OdedRechavi]

PI asked to do research, teach, and take care of the budget
https://t.co/ynfCohG4ul

[Al Charest Lab @AlCharestLab]

Happy to share our newest publication in @NatImmunol
Congratulations to all authors, so proud to be your colleague. Full manuscript available here https://t.co/kKbYuaK0J4

[Al Charest Lab @AlCharestLab]

Always a good feeling when the lab gets an NIH NOA ! Very proud of the hard work all the lab members put in day in day out.

[Dana-Farber @DanaFarber]

We are proud to acknowledge the first #GlioblastomaAwarenessDay. Please join us in remembering those that have been taken by this disease, as well as the patients that are currently fighting it. Learn more here: https://t.co/nqK8mRkB3e

[SNO @NeuroOnc]

The #glioblastoma patient population is in desperate need of new and better therapeutic options. Join the brain tumor community as we aim to raise awareness and find treatments on the first-ever #GBMDay - July 17! #BTSM

[Al Charest Lab @AlCharestLab]

Today is GBM day. Learn about this intractable cancer at #GBMday

[Al Charest Lab @AlCharestLab]

Impressive work from the ⁦@RonDePinho⁩ lab on how the genetic makeup of #glioblastoma dictate the composition of the TME. Symbiotic Macrophage-Glioma Cell Interactions Reveal Synthetic Lethality in PTEN-Null Glioma: Cancer Cell https://t.co/6p9xkTTHah

[Al Charest Lab @AlCharestLab]

Post-doc position available in the Charest Lab to advance the field of #ExtracellularVesicle #exosome ! Send in your CV. The position is open and available immediately.

[Al Charest Lab @AlCharestLab]

Congratulations to Dr. Aron Gyuris (and all of our colleagues) for publishing his work today on #ExtracellularVesicle #MV #EV in @CellReports

[Al Charest Lab @AlCharestLab]

Physical and Molecular Landscapes of Mouse Glioma Extracellular Vesicl... https://t.co/qejlxjxoH0

[Al Charest Lab @AlCharestLab]

Our review paper with my esteemed colleague and co author Dr. Vicki Boussiotis on immuno therapies made the list!

[Oncogene Journal @oncogenejournal]

Have you checked out our 'Brain Tumors Web Focus' yet?
If not, have a look at this nice collection of #oncogenejournal papers that helped change the landscape in brain tumor research. #cancer #CancerResearch

https://t.co/5hIDXYoaeN

[Al Charest Lab @AlCharestLab]

A nice and quick read on the status of various forms of #immunotherapy for #glioblastoma

[National Cancer Institute @theNCI]

Can #immunotherapy succeed in glioblastoma? A research update on efforts to use the immune system to treat brain cancer: https://t.co/3fmGDif0HA #CancerCurrents

[Al Charest Lab @AlCharestLab]

Amazing line up of speakers! https://t.co/SxI6FPe4w9

[Al Charest Lab @AlCharestLab]

Amazing piece of work from the Sweet-Cordero’s lab. Congrats Alejandro!

[Cancer Discovery @CD_AACR]

Just published: Targeting patient-specific somatic copy number alterations reduces tumor burden in #osteosarcoma patient-derived xenografts @UCSF https://t.co/UMvQASDmQH

[Roel Verhaak @roelverhaak]

For anyone using https://t.co/9dGJ695Nkx: the site is currently down and we are working on bringing it up again. We are also re-engineering the site to increase stability. Apologies for inconvenience.

[Al Charest Lab @AlCharestLab]

Several lines of evidence point to the multi-functionability of extracellular vesicles like #exosomes

[National Cancer Institute @theNCI]

Some tumors may evade the immune system by secreting small membrane-encased sacs called #exosomes: https://t.co/FJnBi4YCzn #immunotherapy

[Al Charest Lab @AlCharestLab]

In cancer, we now know the most common mutations in protein coding genes thanks to the #TCGA. I suspect that the bulk of mutations are found in those 10% of most studied genes with few mutations in the 90% less “popular” genes

[PLOS Biology @PLOSBiology]

Which genes are hot... and which genes are not? Massive study of gene-specific bias in publication and funding shows that most human research is done on just 10% of genes, and predicts the most promising neglected gems #PLOSBiology https://t.co/jYxqjpahGK

[Al Charest Lab @AlCharestLab]

Congratulations Pasi ! Well deserved!

[ESMO - Eur. Oncology @myESMO]

Huge congratulations to the distinguished winners of the ESMO Awards 2018 - @jsoriamd, @TonyMok9, Pasi A. Jänne and Margaret Foti, in recognition of their outstanding contribution to oncology https://t.co/C0uUi2aBSc

[Al Charest Lab @AlCharestLab]

Nice approach towards eventually controlling off-target effects of crispr-cas9-based editing

[Nature Portfolio @NaturePortfolio]

A system to effectively identify genome-wide off-target effects from CRISPR–Cas9 genome editing has been tested in mice in a paper published in Nature. These findings could facilitate research into the clinical translation of genome editing. https://t.co/azMSpGJzeq

[Kevin Haigis Lab @KevinHaigisLab]

Beautiful paper from @SageJulien and colleagues demonstrating the power of GEMMs. There truly are important discoveries to be made from autochthonous mouse models.