Alba

#bio

[AlfonsoValencia alfonsovalencia.bsky.social @Alfons_Valencia]

I love this part on coevolution derived constraints ;-))

[Ewan Birney @ewanbirney]

So @JeremyFarrar asked for an "explainer thread" on Noble Prizes in Chemistry around AlphaFold and Protein design, so here goes.

[Ewan Birney @ewanbirney]

@emblebi Like all Noble Prizes, selecting 3 people - even just in the big teams around them - seems a bit weird - let alone the key people stretching back - John Moult and the CASP team; Chris Sander and @Alfons_Valencia on evolutionary signals/co-evolution in the 1990s

[Alba @Albalepore]

@JamesLucasIT Related https://t.co/xUzJB21FuV

[Leonid Kruglyak @leonidkruglyak]

@TriggerLoop @RyanDhindsa @RMeyerSchuman And that's a serious technical problem that probably entirely explains the results. This is a crude way of looking at it, but the real signal is below the red line and it's nearly all non-synonymous

[JekerLab @JekerLab]

Today! Folks at FOCIS. Check out our work on how to Protect Therapeutic Cells From Targeted Immunotherapy. Presented by Anna Devaux https://t.co/pWUTd42uJE

[sciCORE @sciCORE_Basel]

sciCORE supports #SUCHO! sciCORE is teaming up with @DaSCHSwiss , and @UBBasel to offer a mirror of Ukrainian cultural heritage data collected in the SUCHO initiative 👉https://t.co/vmVgNO83I8 .
@UniBasel_en #SUCHO #UniversityOfBasel #Ukraine

[sciCORE @sciCORE_Basel]

Looking for the next step in your career🚀? Join our Team! Our Center for #DataAnalytics at University of Basel is looking for experts in machine learning/ advanced statistics 👉 https://t.co/Py5PoiYwZU
@UniBasel_en @ISBSIB @DHLabBasel

[Alex Cagan @ATJCagan]

As a scientist and an illustrator having our article featured on the cover of @Nature is a dream come true
I've done an illustrated tweetorial, so this is the illustrators' tweetorial.

[Cimeio Therapeutics @Cimeio]

So excited to introduce Cimeio Therapeutics! With technology discovered at @JekerLab, incubation at Ridgeline Discovery, and Series A funding from @VersantVentures, we aim to transform HSC transplant.
https://t.co/8F2SgbBNaz

[Michelle Trenkmann @MT_Genetics]

Also in @Nature this week: a computational method called EVE (evolutionary model of variant effect) which predicts the functional effects of genetic variants based on evolutionary conservation and sequence context without clinical labels and supervision
https://t.co/uI35mpEy6D

[Andrea Capocci @andcapocci]

Dal dipartimento di fisica della Sapienza.

[The Nobel Prize @NobelPrize]

BREAKING NEWS:
The Royal Swedish Academy of Sciences has decided to award the 2021 #NobelPrize in Physics to Syukuro Manabe, Klaus Hasselmann and Giorgio Parisi “for groundbreaking contributions to our understanding of complex physical systems.”

[Josep Carreras Leukaemia Research Institute (IJC) @CarrerasIJC]

🆕 Resarchers from @ManelEsteller lab show that #epigenetics predicts the efficacy of CAR-T treatments in hematological malignancies.
Find out more about this article, published in @JNCI_Now, @theNCI, @OUPAcademic.
➡️ https://t.co/psYpKDoAIG

[Eric Topol @EricTopol]

This will go down in history as one of science and medical research's greatest achievements. Perhaps the most impressive.
I put together a preliminary timeline of some key milestones to show how several years of work were compressed into months.

[ChimeraX (bsky: chimerax.ucsf.edu) @UCSFChimeraX]

The human muscle protein titin predicted by AlphaFold, 34350 residues.

[Alfredo Iacoangeli @AlfredoIacoange]

I'm excited to see our MachineLearning work on human disease genetics out in NAR https://t.co/38lmteyV5F DGLinker predicts new candidate genes given a set of known disease genes.Great team effort JiajingHu et al @Nicole22874565 @_danbean @Albalepore @AmmarAlChalabi @richdobson

[Alba @Albalepore]

ERC grantee Giorgio Parisi wins prestigious Wolf Prize in physics | ERC: European Research Council @giorgioparisi https://t.co/5I24C8jVWK