Alex Kumachev

General Internal Medicine | Clin Pharm & Tox | Quality Improvement @UofTDOM

[Tony Breu @tony_breu]

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Why can't you use direct oral anticoagulants (DOACs) in patients with mechanical valves (MVs)?

DOACs have been one of the most important advances in my career. And yet, the presence of a MV is one of the few contraindications.

The reason highlights the unique nature of thrombus formation in those with a MV and provides insights into the evolution of human hemostasis.

[David Juurlink @DavidJuurlink]

Now THAT is a prescribing cascade

@CarolynTanMD

[David Juurlink @DavidJuurlink]

Canadian MDs are relying less on opioids. That is a good thing. New commentary from me in @CMAJ
https://t.co/kvPrT6jmg3

[Amit Segal @AmitSegal]

The 6 victims of today’s terror attack in Jerusalem.

Sarah (Saritah) Mendelson, 60
Rabbi Levi Yitzhak Pash
Yaakov Pinto, 25
Rabbi Mordechai Shteintzag, 79
Israel Mencer, 28
Rabbi Yosef David, 43

May their memories forever be a blessing.

[Alex Kumachev @AlexKumachev]

@johnmarkowsky @DavidJuurlink Hi John, unfortunately we are unable to provide a virtual option this year due to the accreditation process through our continuing education office

[David Juurlink @DavidJuurlink]

Toronto-area MDs and pharmacists: Join us for Therapeutics Day 2025

- Relevant topics
- Great speakers
- You will be fed
- You will get CE credits

To register: https://t.co/fkJrmsWOwS

[Hen Mazzig @HenMazzig]

Gadi Haggai, 72, and Judi Weinstein-Haggai, 70, moved to Kibbutz Nir Oz 30 years ago.

According to the kibbutz, Judi was volunteering there when she first heard Gadi playing the flute, and fell in love.

They had four children and seven grandchildren.

Judi, a dual American-Israeli citizen, was an English teacher specializing in children with special needs. She worked with children suffering from anxiety, using meditation and mindfulness techniques. She loved writing poetry and was also an entrepreneur.

Gadi was a gifted musician from the age of three, a talented chef, and a man deeply connected to the land. Together with Judi, he led a healthy, active lifestyle.

Both were devoted believers in peace and coexistence.

On the morning of October 7, while on their regular walk near the kibbutz, Hamas terrorists opened fire. The couple sought shelter under a tree in the fields.

Gadi was shot and killed. Judi, severely wounded, managed to call for help.

An ambulance was dispatched, but it was hit by a missile and never arrived. Gadi and Judi died in that field.

Shortly afterward, the terrorists returned and took their bodies into Gaza.

The terror cell responsible for this atrocity is the same unit that kidnapped and murdered Shiri, Ariel, and Kfir Bibas.

Today, thanks to intelligence efforts, the IDF recovered Judi and Gadi’s bodies in the Khan Younis region.

May their memories be a blessing. 🕯️

[Alex Kumachev @AlexKumachev]

@YoniFreedhoff

[Tony Breu @tony_breu]

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In today's Morning Report, I learned that DRESS is associated with the reactivation of herpesviruses, particularly HHV-6.

Whether this or other herpesviruses are part of the pathogenesis of DRESS or a consequence of DRESS remains unsettled.

https://t.co/4G3mXhNPcQ

[David Juurlink @DavidJuurlink]

Toronto-area MDs and pharmacists: Join us for Therapeutics Day 2024

- Relevant topics
- Great speakers
- You will be fed
- You will get CE credits

Space is limited. Register here: https://t.co/aWXChi9vl3

[Michael Fralick @FralickMike]

Want to learn more about drug interactions but not sure where to start? Great upcoming conference by @DavidJuurlink @JonZipursky @CarolynTanMD @AlexKumachev @Pete_Wu et al!

https://t.co/namSlMQnpj

[Aviva Klompas @AvivaKlompas]

Rachel Goldberg-Polin: "Ok sweet boy, go now on your journey. I hope it's as good as the trips you dreamed about because finally, my sweet boy, finally, finally, finally, finally you are free.

I will love you and I will miss you every single day for the rest of my life, but you're right here. I know you're right here. I just have to teach myself how to feel you in a different way.

And Hersh there is one last thing I need you to do for us. Now I need you to help us stay strong and I need you to help us survive"

[Alex Kumachev @AlexKumachev]

These altered images were then shared by physicians in Ontario. Physicians who are described as heroes, and having integrity.

[Drew Pavlou 🇦🇺🇺🇸🇺🇦🇹🇼 @DrewPavlou]

One of the most evil things I’ve ever seen from an anti-Zionist account: She edited Paragraph 95 of the UNHCR report to censor the part where the UN found patterns of sexual violence against Israeli women on October 7.

So so shameless.

[Alex Kumachev @AlexKumachev]

RT @BarakRavid: BREAKING: Israeli soldiers retrieved the bodies of three hostages who were killed by Hamas on October 7 and their bodies we…

[Yoni Freedhoff @YoniFreedhoff]

14 women are still being held hostage in Gaza.

[Alex Kumachev @AlexKumachev]

Am Yisrael Chai. #BringThemHomeNow

[Yoni Freedhoff @YoniFreedhoff]

#BringThemAllHome #100Days

[The Persian Jewess @persianjewess]

Jonny Siman Tov, a wheat farmer, and his wife Tamar, a women’s rights activist, were hiding in a safe room w/ their 4 yo son and 6 yo twin daughters.

Jonny texted his sister: "They're here. They're burning us. We're suffocating."

The whole family was burned alive, to ashes.

#IStandWithIsrael
#HamasRapists
#BringThemHomeNow
#BelieveIsraeliWomen
#NeverAgainIsNow