Alexander Mahnert🇪🇺🇺🇦

Microbiome researcher at the Medical University of Graz | focused on confined built environments | human associated archaea | applied bioinformatics and PP

[Alexander Mahnert🇪🇺🇺🇦 @AlexMahnert]

@gilbertjacka Congrats Jack!

[Alexander Mahnert🇪🇺🇺🇦 @AlexMahnert]

@gilbertjacka @NOAA @Scripps_Ocean Fantastic! Congrats Jack 💪

[Alexander Mahnert🇪🇺🇺🇦 @AlexMahnert]

@gilbertjacka The evening was a blast. Thanks Jack. Happy to continue our collaborations!

[Jack A Gilbert (he/him/his) @gilbertjacka]

Lovely hanging with @AlexMahnert yesterday! Science for the win!

[Alexander Mahnert🇪🇺🇺🇦 @AlexMahnert]

@gibbological @gilbertjacka cute you two 🤩

[Alexander Mahnert🇪🇺🇺🇦 @AlexMahnert]

@abgradeurope

[Alexander Mahnert🇪🇺🇺🇦 @AlexMahnert]

Happy to host europes astrobiology community this week in Graz 😍 https://t.co/yhCgPNB7Dl
With great creative formats like its Space Factor contest! 👍

[Alexander Mahnert🇪🇺🇺🇦 @AlexMahnert]

Today acting as the chair for the Mars 1 and 2 sessions, and looking forward to tomorrow's #BioTechMed-Graz supported planetary protection session, where I'll present some results from our ProConTra project!

[Christine Moissl-E @chmoei]

New #archaeome paper alert! Growing human #archaea is sometimes really a pain, but we found a way to cultivate Methanobrevibacter species in a very targeted way: https://t.co/lUSyDZl4PC

[Christine Moissl-E @chmoei]

It took 10 years of research to finally prove the presence of archaea on human skin. What a challenging yet thrilling journey! Big thanks to @Archaea_Vienna for the amazing collaboration, discussions, and dedication to our shared vision. 🙌🔬 #ResearchJourney #Collaboration

[Christine Moissl-E @chmoei]

Overall, Nitrosocosmicus archaea are proving to be integral, stable components of the human #skin #microbiome. Their unique adaptations and interactions with our skin open new doors for understanding skin health and and the biology or archaea.

[Christine Moissl-E @chmoei]

Co-occurrence network patterns show these AOA interact with specific skin bacteria, reinforcing their role in a balanced skin microbiome. This relationship suggests they play a key role in maintaining skin health.

[Christine Moissl-E @chmoei]

In our study with 47 individuals, we found these AOA strains consistently present in both cross-sectional and longitudinal samples. Their stability on the skin highlights their role as emerging commensals.

[Christine Moissl-E @chmoei]

Genomic analysis reveals special adaptations, including unique gene families and interactions with host proteins. These adaptations help them colonize skin effectively and maintain their presence, especially in sebaceous areas.

[Christine Moissl-E @chmoei]

These AOA strains are autotrophic, meaning they use ammonia and urea as their sole energy sources. This unique metabolic capability allows them to thrive on our skin, where nutrients are quite different from their usual soil environments.

[Christine Moissl-E @chmoei]

Archaea on skin? YES! We’ve tracked and isolated two new strains of ammonia-oxidizing archaea (AOA) from human skin: Nitrosocosmicus epidermidis and Nitrosocosmicus unguis. Here’s what makes them fascinating. 👇 #Microbiome #SkinHealth

[Christine Moissl-E @chmoei]

‼️Exciting news this morning! Our new preprint on human skin #archaeome is online. A great collaboration with the Schleper lab @Archaea_Vienna, spearheaded by @AlexMahnert supported by many colleagues and friends! 👇Details: https://t.co/ovUOEJ5nrO