Alok Jha

Always thinking!

[Alok Jha @AlokGene]

My recent publication in Frontiers in Immunology”Extracellular caspase-1: a critical inducer and a therapeutic target of lung injury in gut ischemia-reperfusion” https://t.co/XsqcsfSNSF

[Alok Jha @AlokGene]

My recent publication in Molecular Medicine “A novel CD112-derived peptide targeting gut-primed neutrophils to attenuate deadly hepatic injury”.

https://t.co/AACbZgdrIu

[Frontiers - Immunology @FrontImmunol]

New Research: B-1a cells mitigate radiation injury by protecting intestinal barrier integrity https://t.co/aDpnwKbXAi #FrontiersIn #Immunology

[Journal of Clinical Investigation @jclinicalinvest]

@AlokGene @NorthwellHealth DLL4+ neutrophils promote Notch1-mediated endothelial PANoptosis to exacerbate acute lung injury in sepsis

[Journal of Clinical Investigation @jclinicalinvest]

Can we disrupt the amplification of systemic inflammation in #sepsis?

Alok Jha @AlokGene, Ping Wang & team @NorthwellHealth find a unique neutrophil subpopulation expressing high DLL4 induces pulmonary endothelial cell PANoptosis, exacerbating acute lung injury. And treatment with a notch inhibitor in septic mice… 👇 https://t.co/jVQqDWQ9y2

Image (1/2) shows mouse lung tissue with elevated damage (indicated by ZBP1, red) in tissue from sepsis mouse models with DLL4+ neutrophil injections; and survival rates (2/2) in septic mice following treatment.

[Alok Jha @AlokGene]

My recent publication in “The Journal of Clinical Investigation (JCI)” “DLL4+ neutrophils promote Notch1-mediated endothelial PANoptosis to exacerbate acute lung injury in sepsis”. https://t.co/b5dROr6e74

[Alok Jha @AlokGene]

My recent publication in Nature Communications “ Gut-primed neutrophils activate Kupffer cells to promote hepatic injury in mouse sepsis”
https://t.co/Y31rSXKAA5

[Alok Jha @AlokGene]

I thought Time could be more than just one way-flow. Here Scientist Proposes ‘Three-Dimensional Time’ Theory. https://t.co/Gm8WSevHrP

[Alok Jha @AlokGene]

My recent publication in Molecular Medicine “The role of an anti-inflammatory molecule AIM/CD5L in gut ischemia/reperfusion injury of male mice.”

https://t.co/2VLnDHN96S

[Alok Jha @AlokGene]

@NobelPrize Congratulations.

[Alok Jha @AlokGene]

My recent publication in “Advanced Science”- “Critical Role of IL1R2‐ENO1 Interaction in Inhibiting Glycolysis‐Mediated Pyroptosis for Protection Against Lethal Sepsis” - Advanced Science - Wiley Online Library https://t.co/dKdrJmq7aC

[Alok Jha @AlokGene]

@EyeDaisyShu @MetabolitesMDPI @lennikov @MengluYangMD @gammaDave1 Congratulations.

[Alok Jha @AlokGene]

@ClaireMax Great!

[Alok Jha @AlokGene]

My recent publication “Identification of a multiple DAMP scavenger mimicking the DAMP-binding site of TLR4 to ameliorate lethal sepsis” https://t.co/NL7E8ZMMyo

[Frontiers - Immunology @FrontImmunol]

New Research: Identification of a multiple DAMP scavenger mimicking the DAMP-binding site of TLR4 to ameliorate lethal sepsis https://t.co/nPYEo39ZMt #FrontiersIn #Immunology

[Alok Jha @AlokGene]

@EyeDaisyShu @ASIPath @WomeninPath @UNSWoptomvsci Congratulations!

[Alok Jha @AlokGene]

@EyeDaisyShu @ASIPath @WomeninPath @AmyEngevik @micromindy @MengluYangMD @thekengevik Great!

[World Governments Summit @WorldGovSummit]

@AlokGene Day 3 | World Governments Summit 2025 – Ministerial meetings, future solutions, and exceptional opportunities for governments. Global leaders are presenting new insights.

Join the Conversation.

#WorldGovSummit #WGS2@AlokGene Day 3 | World Governments Summit 2025 – Ministerial meetings, future solutions, and exceptional opportunities for governments. Global leaders are presenting new insights.

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#WorldGovSummit #WGS2@AlokGene Day 3 | World Governments Summit 2025 – Ministerial meetings, future solutions, and exceptional opportunities for governments. Global leaders are presenting new insights.

Join the Conversation.

#WorldGovSummit #WGS2@AlokGene Day 3 | World Governments Summit 2025 – Ministerial meetings, future solutions, and exceptional opportunities for governments. Global leaders are presenting new insights.

Join the Conversation.

#WorldGovSummit #WGS2@AlokGene Day 3 | World Governments Summit 2025 – Ministerial meetings, future solutions, and exceptional opportunities for governments. Global leaders are presenting new insights.

Join the Conversation.

#WorldGovSummit #WGS2@AlokGene Day 3 | World Governments Summit 2025 – Ministerial meetings, future solutions, and exceptional opportunities for governments. Global leaders are presenting new insights.

Join the Conversation.

#WorldGovSummit #WGS25

[World Governments Summit @WorldGovSummit]

@AlokGene Day 2 | World Governments Summit 2025 – Discussions happening now! Artificial intelligence, government efficiency, and emerging economies.

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#WorldGovSummit #WGS2@AlokGene Day 2 | World Governments Summit 2025 – Discussions happening now! Artificial intelligence, government efficiency, and emerging economies.

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#WorldGovSummit #WGS2@AlokGene Day 2 | World Governments Summit 2025 – Discussions happening now! Artificial intelligence, government efficiency, and emerging economies.

Join the Conversation.

#WorldGovSummit #WGS2@AlokGene Day 2 | World Governments Summit 2025 – Discussions happening now! Artificial intelligence, government efficiency, and emerging economies.

Join the Conversation.

#WorldGovSummit #WGS2@AlokGene Day 2 | World Governments Summit 2025 – Discussions happening now! Artificial intelligence, government efficiency, and emerging economies.

Join the Conversation.

#WorldGovSummit #WGS2@AlokGene Day 2 | World Governments Summit 2025 – Discussions happening now! Artificial intelligence, government efficiency, and emerging economies.

Join the Conversation.

#WorldGovSummit #WGS25

[World Governments Summit @WorldGovSummit]

@AlokGene Day 1 | World Governments Summit 2025 | More than 30 heads of state and government, 400 ministers, and top global business leaders are gathering to envision a better future for humanity.

Join the Conversation.

#WorldGovSummit #WGS2@AlokGene Day 1 | World Governments Summit 2025 | More than 30 heads of state and government, 400 ministers, and top global business leaders are gathering to envision a better future for humanity.

Join the Conversation.

#WorldGovSummit #WGS2@AlokGene Day 1 | World Governments Summit 2025 | More than 30 heads of state and government, 400 ministers, and top global business leaders are gathering to envision a better future for humanity.

Join the Conversation.

#WorldGovSummit #WGS2@AlokGene Day 1 | World Governments Summit 2025 | More than 30 heads of state and government, 400 ministers, and top global business leaders are gathering to envision a better future for humanity.

Join the Conversation.

#WorldGovSummit #WGS2@AlokGene Day 1 | World Governments Summit 2025 | More than 30 heads of state and government, 400 ministers, and top global business leaders are gathering to envision a better future for humanity.

Join the Conversation.

#WorldGovSummit #WGS2@AlokGene Day 1 | World Governments Summit 2025 | More than 30 heads of state and government, 400 ministers, and top global business leaders are gathering to envision a better future for humanity.

Join the Conversation.

#WorldGovSummit #WGS25