Our genes can have an impact on our lifespan.
However, in a study involving 353,752 adults it was found that a healthy lifestyle can overcome 62% of the genetic risk of a shorter life.
- Over a 13 year period, involving 24,239 deaths, participants were grouped into long, intermediate and short lifespan risks based on a polygenic score of known lifespan influencing genes.
- Their lifestyle was also grouped into favourable, intermediate and unfavourable, based on several factors. The 4 most important were smoking status, sleep, activity level and diet.
- Over the 13 years, those with the short lifespan risk and unfavourable lifestyle were twice as likely to die as those with the long lifespan risk and favourable lifestyle.
- However, the study suggests that those with a short lifespan risk could extend their life expectancy by nearly 5.5 years at the age of 40 with the implementation of a healthy lifestyle.
PMID: 38684374
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