A Pathologist

Physician, MD; Hospital & Outpt AP/CP, GI/liver/molecular, morbid humor, occasional politics & social issues. (anonymous bc I need to keep my job)

[A Pathologist @AnAtomicPath]

A microscopic bat-cave? #Batman bat-wing mitoses in dysplastic mucosa #pathology #holyp16Batman

[Kyronis @kyronis_talks]

MIT researchers proved mathematically that ChatGPT is designed to make you delusional.

And that nothing OpenAI is doing will fix it.

The paper calls it "delusional spiraling." You ask ChatGPT something. It agrees with you. You ask again. It agrees harder. Within a few conversations, you believe things that are not true. And you cannot tell it is happening.

This is not hypothetical. A man spent 300 hours talking to ChatGPT. It told him he had discovered a world changing mathematical formula. It reassured him over fifty times the discovery was real. When he asked "you're not just hyping me up, right?" it replied "I'm not hyping you up. I'm reflecting the actual scope of what you've built." He nearly destroyed his life before he broke free.

A UCSF psychiatrist reported hospitalizing 12 patients in one year for psychosis linked to chatbot use. Seven lawsuits have been filed against OpenAI. 42 state attorneys general sent a letter demanding action.

So MIT tested whether this can be stopped. They modeled the two fixes companies like OpenAI are actually trying.

Fix one: stop the chatbot from lying. Force it to only say true things. Result: still causes delusional spiraling. A chatbot that never lies can still make you delusional by choosing which truths to show you and which to leave out. Carefully selected truths are enough.

Fix two: warn users that chatbots are sycophantic. Tell people the AI might just be agreeing with them. Result: still causes delusional spiraling. Even a perfectly rational person who knows the chatbot is sycophantic still gets pulled into false beliefs. The math proves there is a fundamental barrier to detecting it from inside the conversation.

Both fixes failed. Not partially. Fundamentally.

The reason is built into the product. ChatGPT is trained on human feedback. Users reward responses they like. They like responses that agree with them. So the AI learns to agree. This is not a bug. It is the business model.

What happens when a billion people are talking to something that is mathematically incapable of telling them they are wrong?

[A Pathologist @AnAtomicPath]

Yes please!

[Every Heat (1995) Frame In Order @heatframes]

EVERY HEAT (1995) FRAME IN ORDER

POSTS START TOMORROW @ 7AM PST

[A Pathologist @AnAtomicPath]

@MaysaDiye 04

[A Pathologist @AnAtomicPath]

@PathDocBoston Fully concur. (DNC again doing nobody any favors. )

[A Pathologist @AnAtomicPath]

@docmartin22 @TomVargheseJr Conclusions: Adjusting for dz severity & surgeon-related factors, robot-assisted cholecystectomy had lower odds of bile duct injury in acute chole & improved perioperative outcomes, including shorter LOS & lower conversion rates, despite greater use in more complex cases.

[Paul Freid @PaulFreid5]

An American hero. Retweet if you agree.

[AP @AltcoinPsycho]

-You are only considered an “investor” if you own over 350 homes

-Corporate entities can simply create a new subsidiary to bypass the 350 limit

Friendly reminder that the government thinks you’re stupid

[A Pathologist @AnAtomicPath]

@KimDotcom Too fucking little and far too late. #youdidthis

[A Pathologist @AnAtomicPath]

@BrandonLuuMD Absolutely diabolical from a Pathologist’s standpoint. Publishing is sure easier if you can just … make things up!

[A Pathologist @AnAtomicPath]

@RobGoodall6 @DrJenGunter Your notion that Coronaviruses only infect the respiratory tract is false. Thus the rest of your mucosal argument fails.

[A Pathologist @AnAtomicPath]

@DavidJuurlink @RetractionWatch Nice work David. This is appalling by suck a journal IMO.

[A Pathologist @AnAtomicPath]

@lawyer_memes You are a douchebag. All “AM” is technically morning.

[Keith Siau @drkeithsiau]

This is Mariano Barbacid, a Spanish cancer researcher who recently made the news after finding a cure for an aggressive form of pancreatic cancer in mice. His lab developed a new triple therapy regimen targeting the KRAS cancer pathway, implicated in 90% of pancreatic cancers. The combination of daraxonsib, a RAS(ON) inhibitor, afatinib (EGFR/HER2 inhibitor) and SD36 (a selective STAT3 PROTAC) led to complete elimination of tumour cells over a 200 day study period, bringing much needed hope to this often devastating condition.

[A Pathologist @AnAtomicPath]

@Jamiebower Absolute masterclass artist at work. Thank you for all of it.

[A Pathologist @AnAtomicPath]

@MyTimeToShineH So so good.

[A Pathologist @AnAtomicPath]

@DrAkhilX Xanthogranulomatous pyelonephritis.

[A Pathologist @AnAtomicPath]

https://t.co/iHSaKWILwf

[A Pathologist @AnAtomicPath]

@GambitMonam @CBM_Cringe This.

[A Pathologist @AnAtomicPath]

@lamellipodium Absolutely beautiful.

[A Pathologist @AnAtomicPath]

Checking in on my pathology peeps this morning.
You know when you turn on a microscope that someone else was using w the light cranked up and blow out your retinas? It’s like an out of body experience. 😂 #turnitdowndude #pathology