Arina Andreyeva

Belarusian, 24/7 immunologist, part-time interpreter and tennis/F1 fan

[Arina Andreyeva @AndreyevaAri]

We are on the cover of @JCI_insight 🎉 Wow! 🥹
Such a special moment for the whole team after so much work, experiments, and persistence. ❤️🔬 Couldn’t be happier to see this project being celebrated this way!

[JCI insight @JCI_insight]

Presenting the first mouse model of #AddisonsDisease: https://t.co/PWDjIAbWPb

This issue’s Cover features work from Arina Andreyeva @AndreyevaAri, @ondrejStepanek, @AdaptiveImmuni2, et al., reporting on how immune cells destroy the adrenal glands in Addison's disease and identifying IFNG as a promising target for future therapies.

The cover image shows an adrenal section from a mouse with experimental autoimmune adrenalitis five months after immunization with CYP11A1-derived peptides. Granulomatous lesions appear as green due to intrinsic autofluorescence. Nuclei (DAPI, blue); steroidogenic adrenocortical cells (CYP11A1, red).

[Arina Andreyeva @AndreyevaAri]

Our paper is now finally published in JCI Insight! 🎉

We present the first mouse model of autoimmune Addison’s disease, revealing sex-specific disease differences and a key role for IFNG-driven adrenal inflammation.

📄 https://t.co/FC4C3BFfFz

#AddisonsDisease #Immunology

[Ondrej Stepanek - Lab of Adaptive Immunity @AdaptiveImmuni2]

Happy to share our latest preprint. We revisited the role of LCK in cytotoxic T cells. LCK-deficient T cells showed limited proliferation in vivo, but unexpectedly enhanced effector T-cell formation.
https://t.co/ucGXieBBRf

[Arina Andreyeva @AndreyevaAri]

@CYImmunologists @imgprague

[Arina Andreyeva @AndreyevaAri]

Happy to share new preprint from our lab @AdaptiveImmuni2 about the first mouse model of Addison’s disease (Experimental Autoimmune Adrenalitis). We show short-&long-term changes mirroring human pathology and the key role of IFNG-producing CD4+ T cells. https://t.co/zyzmjWf37g

[Arina Andreyeva @AndreyevaAri]

Another great event organized by @CYImmunologists ❤️ Tattoos of your favorite immune cells? Yes please!
Happy International Immunology Day. Even though it’s hard, it’s still the best 🦠

[Arina Andreyeva @AndreyevaAri]

@science_charles @HonzaDobes87 @CharlesUniPRG Wow! Congrats! 🎉

[Arina Andreyeva @AndreyevaAri]

I am glad to be chosen to participate and represent our lab @AdaptiveImmuni2 and @CzechAcademy at the Summer School of Single Cell in Pilsen. 8 active days ahead.

[Arina Andreyeva @AndreyevaAri]

Our project was presented at the European Congress of Immunology 2024 in Dublin. I couldn't attend in person, but wow, I'm so glad more and more people are learning about our research ✨

[Arina Andreyeva @AndreyevaAri]

An amazing work done in our lab ❤️

[EMBO Reports @emboreports]

Ondrej Stepanek @AdaptiveImmuni2 @imgprague and co-workers show that  adaptor protein ABIN1 is a negative regulator of effector functions in cytotoxic #Tcells by restricting p38 activation. #immunity

https://t.co/QBCkzR0xOY

[Ondrej Stepanek - Lab of Adaptive Immunity @AdaptiveImmuni2]

Happy to share our latest publication, showing that #ABIN1 aka #TNIP1 is a negative regulator of antigenic and co-stimulation signaling in primary CD8+ T cells.
https://t.co/KBnQ9OkqNV
Congrats to Sarka and other contributing authors from our lab and from the @CZphenogenomics!

[Arina Andreyeva @AndreyevaAri]

I was very excited to share our latest results on a very cool project :)

[Ondrej Stepanek - Lab of Adaptive Immunity @AdaptiveImmuni2]

Congratulations to our student @AndreyevaAri who won the best poster prize at the poster session for 1st year Immunology MSc. students at @science_charles. She works on the development and characterization of a new mouse model of Addison's disease.