Anna_Tcc

Ph.D at @IREISGufficiale - I’m a supporter of the dual role of IFN-I in cancer and now I’m struggling with secretory autophagy.

[Anna_Tcc @AnnaLisaTcc]

I'm really happy to share with you our recent publication in JITC on hMena isoform role in the regulation of IFN-I signaling and resistance to ICB in NSCLC. #nisticòLab @IREISGufficiale

[Journal for ImmunoTherapy of Cancer @jitcancer]

New #JITC article: hMENA isoforms regulate cancer intrinsic type I IFN signaling and extrinsic mechanisms of resistance to immune checkpoint blockade in NSCLC https://t.co/TCjjldlYnr @AnnaLisaTcc

[IRE ISG IFO @IREISGufficiale]

🧬 Giornata Internazionale dell’Immunologia

“Il sistema immunitario ci protegge ogni giorno. Studiarlo nei tumori significa capire perché a volte fallisce e migliorare le immunoterapie” – Paola Nisticò @NisticoLab Resp. Immunologia e Immunoterapia IRE

[IRE ISG IFO @IREISGufficiale]

✋ Il tumore del polmone può creare una barriera contro il sistema immunitario.
Uno studio #IRE identifica nella proteina hMENA un ruolo chiave.
🎯 Obiettivo con @AIRC_it : spezzare la barriera e potenziare l’immunoterapia: https://t.co/BZRj5NdfA3

[TheNisticòLab @NisticoLab]

New study published! We uncover a reciprocal loop between hMENA and TGF-β  signallingin CAFs that fuels EMT, suppresses anti-tumor immunity, correlates with worse prognosis, and drives resistance to immune checkpoint therapy in NSCLC. @jitcancer
https://t.co/j7WvldNNtU

[Jennifer Guerriero, PhD @JennGuerriero]

PSA: Stop calling macrophages in tissue M1 or M2. These are not states that exist in biology. The only use of M1 is a macrophage cultured ex vivo with LPS and IFNg; and for M2: IL-4/13/10. Macrophages in tissues are highly complex and diverse and do not resemble either of the aforementioned M1/M2 states. M1/M2 language causes confusion and sets the field back. Refer to your macrophages by the molecules they express and the cytokines they make.

[Jennifer Guerriero, PhD @JennGuerriero]

I think this might be my best slide yet…
#IYKYK @PCFnews

[IRE ISG IFO @IREISGufficiale]

🧪 Studio ricercatrici IRE
Tumore del polmone: scoperte “fabbriche di difesa immunitaria” 🛡️ che predicono la risposta alla chemio-immunoterapia.
Una paziente con metastasi cerebrale ha ottenuto risposta completa e lunga sopravvivenza.
🔬 Scopri di più: https://t.co/RrtrCUmGTy

[Filippo Gallina @filippog92]

🚨 Just published in @jitcancer: our report on spatial transcriptomics of a resectable NSCLC after neoadjuvant chemo-io. A great multidisciplinary effort by @NisticoLab and @IREISGufficiale! Looking forward to many collaborations in this field.
https://t.co/ok2KiIS5hu

[TheNisticòLab @NisticoLab]

Precision medicine for lung cancer 🫁: a new case report from our institute @IREISGufficiale highlights B cells as crucial players in the response to neoadjuvant chemo-immunotherapy therapy.
@filippog92 @NiclaPorciello @NisticoPaola

[Repubblica @repubblica]

I commenti di oggi: Se Trump distrugge la ricerca [di Alberto Mantovani] #16marzo https://t.co/KRBpWeFVek

[TheNisticòLab @NisticoLab]

European scientists stand united with our American colleagues. We support the #StandUpForScience movement and advocate for sustained funding and policies that empower scientific research worldwide. #sciencenotsilence #scienceforall

[Arun Sharma @ArunSharmaPhD]

Happy Valentine’s Day! Here’s a heart-shaped, stem cell-derived cardiac organoid from @Sean_Escopete in our lab.

Our mini-hearts beat for you! ❤️🫀

[Nik Joshi @Joshilabyale]

My Uber driver found out I’m a cancer research and told me about his father who has been 4 yrs cancer free thanks to a-PD1 immunotherapy (Nivo).

Mentioned how his father got to see his two sons married, meet his grandchildren.

As a scientist, these stories are very inspiring

[Journal of Experimental & Clinical Cancer Research @JournalofExper1]

Read here this interesting Meeting Report
published on JECCR👇

#CancerOrganoids as reliable disease models to drive clinical development of novel therapies
https://t.co/4aVDhWSiUW

#PrecisionMedicine
#Patientderived3Dculturemodel
#PreclinicalModels
#CancerSpheroid

[Sara Bruschini @SaraBruschini1]

Today at @IREISGufficiale @Casanova_Acebes talking about the complexity of macrophages in tumour microenvironment. Such a brilliant and inspiring young PI with an entusiastic view on the macrophages world. A pleasure for young researchers!

[Dr. Catharine Young @DrCatharineY]

Tomorrow I will be voting like science and health depends on it. Because it does.

[IRE ISG IFO @IREISGufficiale]

Congratulazioni a Paola Nisticò, Resp. Immunologia e immunoterapia dei tumori #ReginaElena eletta nuova Presidente NIBIT, Network Italiano per la Bioterapia e Immunoterapia dei Tumori: https://t.co/umnyc9GffI
@NisticoLab @GennaroCiliber1

[Anna_Tcc @AnnaLisaTcc]

@NisticoLab @EMBO Impressive findings! 😍👏

[Anna_Tcc @AnnaLisaTcc]

@NisticoLab @NiclaPorciello @EMBO Well done!! 🤩

[Anna_Tcc @AnnaLisaTcc]

@NisticoLab @bio_lorenzo_ @NisticoPaola @NiclaPorciello Well done Lorenzino 💪🏻🥂🥳 Congratulations!!

[TheNisticòLab @NisticoLab]

The #NIBIT meeting in Palermo was incredible, with outstanding speakers and insightful discussions! And of course, the fantastic food made it even better. Amazing time all around!