Applied Biophysics

Creator of ECIS® 😎 Pioneering impedance-based tools for real-time, label-free cell research and drug discovery. Study cells in vitro with precision and ease.

[Applied Biophysics @AppliedBioPhys]

New 🥳#ECIS research from the @CNSE

This study used ECIS to track how NIH 3T3 fibroblasts and bEnd3 endothelial cells respond to SMA nanoparticles in real time.

📖Full study: https://t.co/yKZbSSaCyv

#BiomedicalResearch #Nanotechnology #CellBiology #BarrierFunction #ECIS

[Applied Biophysics @AppliedBioPhys]

Hyperosmolar stress slashed corneal barrier integrity by up to 69%—but L-carnitine helped restore it.

With #ECIS Z-Theta, researchers showed:
🔹 NaCl cut TER 30–69% & slowed migration
🔹 L-carnitine partly rescued TER & repair

📄Full Paper: 10.1016/j.exer.2025.110499

[Applied Biophysics @AppliedBioPhys]

Using #ECIS Z-Theta, researchers tracked how Müller glial EVs affect RPE barrier function:

🔵 Normoxic EVs: Barrier stable ✅
🟡 Hypoxic EVs: Barrier weakens, TER drops over 72h
💡 #ECIS reveals how hypoxic EVs compromise retinal integrity

Full paper: https://t.co/iXmP9dCUdR

[Applied Biophysics @AppliedBioPhys]

We are saddened to share that our colleague and friend, Dr. Ivar Giaever—Nobel Laureate and co-founder of Applied BioPhysics—passed away peacefully on June 20 at the age of 96. His brilliance, humor, and visionary spirit continue to inspire us. He will be deeply missed. 🕊️💙

[Applied Biophysics @AppliedBioPhys]

🔎 TEERZ doesn’t just give more data—it gives better answers.

📉 Same trend as manual TEER, but with:
✅ Real-time, high-res data
✅ Full 96-well tracking
✅ Zero interruptions

Why settle for snapshots when you can see the full story?

#TEER #TEERZ #ECIS #CellBiology #Biotech

[Applied Biophysics @AppliedBioPhys]

🧬 New #GPCR insights via #ECIS!
UIC researchers show CLIC1/CLIC4 regulate Rac1 in endothelial cells—not through ion channel activity, but via structural domains (C-termini).

📖 Study: https://t.co/0S8Pk8FJwF
🔍 About ECIS TEER: https://t.co/ZhaxJxyTvJ

#BarrierFunction #TEER

[Applied Biophysics @AppliedBioPhys]

Discover how ECIS® evolved from a bold scientific idea into a trusted tool that’s transformed live cell research for over 40 years. ⬇️Link below⬇️#ECIS

🧑‍🔬https://t.co/V3tNLc400M

[Applied Biophysics @AppliedBioPhys]

🧬 Calling all cell biologists & bioengineers! Join us at IBCA 2025 – the 6th Int'l Conference on Impedance-Based Cellular Assays! Register now 👇

📃https://t.co/iOhgdJle2C

#IBCA2025 #CellBasedAssays #ECIS #ImpedanceAssays #CellBiology

[Applied Biophysics @AppliedBioPhys]

🦠New study from Univ. of Regensburg shows how #ECIS tracks virus-induced cytopathic effects in real time—offering a powerful, non-invasive alternative to traditional neutralization assays.

🔗https://t.co/sQbHsZJFWx
#Virology #VirusNeutralization #Biotech #Pseudovirus #Impedance

[Applied Biophysics @AppliedBioPhys]

Want to see what #ECIS can do for your cell research?
🔗 Contact us: https://t.co/ZhaxJxylGb

#SepsisResearch #EndothelialCells #BarrierFunction #RealTimeData #LungInjury #CellScience #BiotechTools

[Applied Biophysics @AppliedBioPhys]

🧪 How do you track lung cell injury in real-time—without disturbing the cells? Easy. Use #ECIS. 😉

Researchers at Shanghai Jiao Tong Univ. studied sepsis-induced lung injury 🫁 and the protective power of telocyte-derived exosomes 🧬—focusing on miRNA-146a-5p & caspase-3.

[Applied Biophysics @AppliedBioPhys]

📚 Full Study: https://t.co/p8imwzIkPN

[Applied Biophysics @AppliedBioPhys]

Exciting new paper from Dr. A. Chowdhury & UQ @MDPIOpenAccess

🧪 Real-time venom research with #ECIS
🐍 Viper & cobra venoms cause cell damage
🛡️ DTIs (varespladib + marimastat) offer protection
⚖️ Supports alternatives to animal testing

📄 Full paper: https://t.co/QeGHXgYWeT

[Applied Biophysics @AppliedBioPhys]

Congratulations to Catherine on graduating from SBA THRIVE 🎉We’re proud of her dedication to leadership, growth, and innovation. Her fresh ideas and strategies inspire our team and drive us forward.🚀Here’s to continued success and impact! #Leadership #Innovation #GrowthMindset

[Applied Biophysics @AppliedBioPhys]

Join us for our upcoming webinar: Barrier Function Assays at 11:00 AM EDT on October 15, 2024 ➡️https://t.co/EaFMMA35Bh

This webinar will discuss how complex impedance measurements with #ECIS can be used to evaluate the barrier function and #TEER of confluent cells.

[Applied Biophysics @AppliedBioPhys]

Watch 🤩our latest video to learn more about #ECIS and follow our page for updates! If you have any questions, let us know in the comments 👩‍🔬
⏩https://t.co/lvTDRcJ33N

[Applied Biophysics @AppliedBioPhys]

Join us for our upcoming webinar: Automated Cell Migration at 11:00 AM EDT on October 1, 2024 ➡ https://t.co/G5VbN8p3c9

This webinar will discuss how the #ECIS system employs electric signals to both wound and monitor the healing process of cells. #sciencetwitter

[Applied Biophysics @AppliedBioPhys]

Join us for our upcoming webinar: Cell Invasion/Extravasation Assays @ 11:00 AM EDT -September 17, 2024 ➡ https://t.co/hLTdMJFvOQ

Topic: Observe the extravasation of cell layers in real-time and record quantitative data regarding the metastatic potential of the cancer cells.

[Applied Biophysics @AppliedBioPhys]

We are excited to announce we have received a 2-year, $1.8M grant from NIH! 🥳 https://t.co/6IK6zYvO0n

The SBIR grant will fund the R&D of the #ECIS Cell Assurance Monitor, a new approach to ensure the quality and integrity of cells grown in vitro. 👩‍🔬🧫

[Applied Biophysics @AppliedBioPhys]

Congrats to our company President, Catherine, for being accepted into the SBA T.H.R.I.V.E. CEO Training Program! She is excited about this opportunity to collaborate with local business owners and learn from business leaders nationwide🥳Huzzah! #smallbiz @ThriveSBA @SBAUpstateNY