Do check out a new preprint from the lab @IISERPune on the bioinformatics analysis and biochemical characterization of ABHD12. Nice work spearheaded by @ArnabChaks & @ArchitDevarajan, with help from @Kundan703 & Rohith.
https://t.co/6HbYT9ht75
The work that I contributed to as a Mitacs Research Intern is now out in @CellReports!! We report the development of a CRISPRi-seq-based technique for chemical-genetic profiling of antimicrobials and identify a novel inhibitor of the essential enzyme peptidyl-tRNA hydrolase.
#InfosysPrize2024 in Life Sciences is awarded to Prof. Siddhesh Kamat, @KamatLab_IISER, of @IISERPune for his discoveries concerning bioactive lipids and their receptors, and their metabolic and signaling pathways. His research using advanced methods to understand the function of lipids, a key component of cells, has important implications for understanding the role of these molecules in a range of cellular functions and human diseases.
Today was @ArchitDevarajan & @ChaitanyaKatka4’s last day in lab @IISERPune. Both have been wonderful & very productive researchers over the past year & now move on to their PhD’s. Looking forward to exciting science from them. (Pic from their farewell lunch today).
My review article has been featured on front cover of the January 2024 issue of @ACSSynBio!
Link to the article:
https://t.co/k10mY2AGK5
@ACS4Authors#MyACSCover
Excited to share my review article on optical-control of #CRISPR-Cas9 and Cre recombinase for gene editing! I talk about the strategies in detail, summarize key challenges & discuss the therapeutic promise of optical-control.
https://t.co/k10mY2AGK5
@iiserbhopal@ACSSynBio
#Breaking: The U.S. FDA approves the CRISPR/Cas9 gene-edited treatment, co-developed with Vertex Pharmaceuticals, for #SickleCellDisease. Learn more: https://t.co/5U9n8WnoV6
Another major milestone towards not being beholden to the misspellings in our DNA. Congratulations to @CRISPRTX, @VertexPharma, the many scientists and doctors who laid the intellectual foundations for this work, and the patients who will benefit from it. 🍻
In vivo base editing works in humans!
Congratulations to @KomorLab, @NicoleGaudelli, and @davidrliu for advancing gene editing science and inventing base editing technology!
Great work by both the @BeamTx team and the Verve team to make it happen! @skathire and @ambellinger 👏🎉
In a major milestone for science, for medicine, and for patients, the world’s first CRISPR drug has been approved in the UK.
“A new treatment for sickle-cell disease and transfusion-dependent β-thalassemia has been authorised by the Medicines and Healthcare products Regulatory Agency (MHRA) for patients aged 12 and over after a rigorous assessment of its safety, quality and effectiveness.”
Congratulations to the many scientists, doctors, patients, and industry leaders who made this development possible.🍻
https://t.co/pUL956YsG3