Differential regulation of histamine H1 receptor-mediated ERK phosphorylation by Gq proteins and arrestins
https://t.co/mjD713mZ4g
#GPCR#signaling#pharmacology
Detection, chemical analysis, and pharmacological characterization of dipyanone and other new synthetic opioids related to prescription drugs
https://t.co/OaArSLc4rx
#GPCR#signaling#pharmacology
Distinct Profiles of Desensitization of µ-Opioid Receptors Caused by Remifentanil or Fentanyl: In Vitro Assay with Cells and Three-Dimensional Structural Analyses
https://t.co/UQA8xnxcFC
#GPCR#signaling#pharmacology
A novel CCR6 antagonist (PF-07054894) that distinguishes between homologous chemokine receptors, increases basal circulating CCR6+ T cells, and ameliorates interleukin-23-induced skin inflammation
https://t.co/PktPDvX1bg
#GPCR#signaling#pharmacology
Dual-Acting Small Molecules: Subtype-Selective Cannabinoid Receptor 2 Agonist/Butyrylcholinesterase Inhibitor Hybrids Show Neuroprotection in an Alzheimer's Disease Mouse Model
https://t.co/RVxPb6YmkB
#GPCR#signaling#pharmacology
Carteolol triggers senescence via activation of β-arrestin-ERK-NOX4-ROS pathway in human corneal endothelial cells in vitro
https://t.co/bzF3hIucan
#GPCR#signaling#pharmacology
Structural Insights into M1 Muscarinic Acetylcholine Receptor Signaling Bias between Gαq and β-Arrestin through BRET Assays and Molecular Docking
https://t.co/HMGAiDkNNu
#GPCR#signaling#pharmacology
Identification of biomarkers, pathways, and potential therapeutic targets for heart failure using next-generation sequencing data and bioinformatics analysis
https://t.co/rvdlK7n9Xw
#GPCR#signaling#pharmacology
Computational insights into ligand-induced G protein and β-arrestin signaling of the dopamine D1 receptor
https://t.co/Q76xClDoxb
#GPCR#signaling#pharmacology