Athena Lane

[William Makis @MakisMedicine]

NEW ARTICLE: METHYLENE BLUE in BREAST CANCER - massive cancer cell killing achieved in this ground-breaking 2017 study

Methylene Blue Week continues! 😃

Now this was a heck of a study! Bet your Oncologist never told you about this one...

2017 Dos Santos et al - Methylene blue photodynamic therapy induces selective and massive cell death in human breast cancer cells

"In this study, we assessed the cell-killing potential of PDT using methylene blue (MB-PDT) in three breast epithelial cell lines... Cells were incubated in the absence or presence of MB and irradiated or not at 640 nm with 4.5 J/cm2"

"We observed that MB-PDT differentially induces massive cell death of tumour cells. Non-malignant cells were significantly more resistant to the therapy compared to malignant cells"

"The highest sensitivity to MB-PDT was observed in MDA-MB-231 cells, used as a model of TNBC (Triple Negative Breast Cancer), a tumour subtype for which there are no targeted treatments"

TNBC cells have lowest reduced glutathione levels compared to all other cell lines - this could be related to the inability of these cells to cope with MB-PDT-induced oxidative stress.

My Take...Highlights:

Methylene Blue targets breast cancer cells but not normal breast cells

Methylene Blue Photodynamic Therapy induces massive cell death of breast cancer cells but only weakly affects normal cells

Triple Negative Breast Cancer cells are most sensitive to killing by Methylene Blue

Multiple cell killing mechanisms are at play but don’t involve mitochondria...Methylene Blue localized not in mitochondria but in lysosomes.

Methylene Blue could be used as an adjunct to breast cancer surgery to “eliminate microscropic residual malignant cells in the post-surgical tumor bed and prevent local as well as metastatic recurrence without affecting normal tissues”

Methylene Blue Photodynamic Therapy could replace Radiation Treatment after breast cancer surgery. (!!)

This was a huge discovery. It was then promptly buried and never spoken of in Oncology again.

Because there is no money in Methylene Blue. 🤔

Those cancer cell killing graphs are stunning!
Have a look! 100% Cancer Cell killing in some cases...

Especially for Triple Negative Breast Cancer!!
(blue bars are normal breast cells, black are breast cancer, red are TNBC)

Methylene Blue week continues...and there are even more shocking articles to come!! Stay tuned! 😃

Article Link in photo to avoid shadowban, just re-type the URL in the first photo at the top, into your browser to access.

@joerogan

[Athena Lane @AthenaLane84]

Trump's UFC 250 is the Greatest Troll in American History. He is the “man in he arena” https://t.co/DHhc6A9coO

[Athena Lane @AthenaLane84]

Trump's birthday proves obsession with age is partisan bias | Opinion https://t.co/rVGzcaiUxj

[🔬 RicardoMontes @_MCRicardo_]

A Narrative Review of the Role of Mitochondria in Cancer: From Metabolic Reprogramming to Therapeutic Targeting

✅️ This review examines the multifaceted role of mitochondria in cancer, integrating initial discoveries w/recent advances from recent studies. It explores how mitochondrial DNA mutations, metabolic reprogramming, & alterations in mitochondrial dynamics contribute to malignant transformation, tumor progression, & therapeutic resistance.

https://t.co/YYPOFHEwoA

Mitochondrial functions in cancer: an integrated overview.

This figure summarizes the major mitochondrial alterations & functions discussed in this review. Central to cancer biology, mitochondria undergo mtDNA mutations, metabolic reprogramming beyond the Warburg effect, altered dynamics including fusion/fission and mitophagy, & ROS/redox signaling changes. These alterations influence the tumor microenvironment & represent therapeutic targets. Collectively, mitochondrial dysfunction enables cancer hallmarks including sustained proliferation, apoptosis resistance, invasion, immune evasion, & therapy resistance.

[John Kass @John_Kass]

HOW THE NEWSPAPER OF RECORD FLUNKED JOURNALISM 101. By Cory Franklin for johnkassnews https://t.co/Obq4Mt3SIT

[Athena Lane @AthenaLane84]

@LangmanVince Then she should choose her outfits more appropriately. Looks like she is starving for money and attention. A has been.

[Karli Bonne’ 🇺🇸 @KarluskaP]

He’s just so darn proud of that reflecting pool 🤣

[Jason Cohen 🇺🇸 @JasonJournoDC]

💥NEW: John Fetterman pushes Kristen Welker to press Graham Platner on s*xting scandal💥

“This is a guy that’s been dropping d*ck pics on Kik for a decade! … the ‘predators’ playground.’ Why can’t someone — perhaps YOU — ask him: ‘Why did you choose Kik!?’”

[Athena Lane @AthenaLane84]

@GOP_is_Gutless Would be a litmus test for sanity

[Tom Fitton @TomFitton]

Woman who stole White House furniture has something to say about "our house."

[Juanita Broaddrick @atensnut]

He does it again. Scott Jennings gets the last word on CNN. 😂👌🏻

JENNINGS: If Elon Musk had never gotten involved in politics, never supported Trump … he’d be getting a ticker tape parade right now.

HINOJOSA: Do you agree that one person should have control in f American policy?

JENNINGS: Call me when you’re mad about Alex Soros.

[Paul A. Szypula 🇺🇸 @Bubblebathgirl]

🎉 Happy 80th Birthday to President Donald J. Trump!

The most resilient leader in U.S. history — and arguably the greatest. His unwavering love for America shines through in everything he does, especially securing our border and putting our country first.

Happy Birthday to the GOAT!

Please keep taking such great care of him, First Lady Melania. 🇺🇸

(Video: AI)

[Athena Lane @AthenaLane84]

@FFT1776 White collar prison would be just fine but send him there!

[Athena Lane @AthenaLane84]

@MrWhiplash_ Sure, Hillary. “Plus one”

[Athena Lane @AthenaLane84]

@speer01369872 @Real_RobN Stealing from hardworking honest Americans who pay taxes

[Dewey Duck @Swmngwshrks]

@Real_RobN Truman knew:

[🇺🇸RealRobert🇺🇸 @Real_RobN]

Here is:

Chairman and editor-in-chief of Forbes, Steve Forbes:

The g’ddamn Somali Ilhan Omar and her white husband are running a money laundering operation in broad daylight.

“It’s amazing how people can go into Congress and then become these entrepreneurial investing geniuses, where they come in, she had under $1,000 of net worth, and her husband didn't have much, and suddenly now they're multimillionaires. Is there a money laundering operation here — something is not right”

“That $30 million came from sources that are illegal, period.”

[Athena Lane @AthenaLane84]

@LangmanVince Saggy butt give away

[Athena Lane @AthenaLane84]

@LangmanVince Covers up the saggy parts. Plastic surgery on head. Trying to look risqué. Young men aren’t interested

[Athena Lane @AthenaLane84]

@TaraBull She must be lonesome. Not in a good relationship and searching. Pitiful actually