Autophagy Articles

Daily updates on autophagy research. Covering macroautophagy, CMA, mitophagy, lysophagy, pexophagy, ER-phagy, aggrephagy, nucleophagy, and xenophagy.

[Autophagy Articles @AutophagyJC]

Hyper-ubiquitylation of DNA helicase RECQL4 by E3 ligase MITOL prevents mitochondrial entry and potentiates mitophagy.
https://t.co/CYbXTeNGlE

[Autophagy Articles @AutophagyJC]

TECPR1 conjugates LC3 to damaged endomembranes upon detection of sphingomyelin exposure.
https://t.co/mr15uepxCI

[Autophagy Articles @AutophagyJC]

TECPR1 is activated by damage-induced sphingomyelin exposure to mediate noncanonical autophagy.
https://t.co/ReeqYhcOj4

[Autophagy Articles @AutophagyJC]

The regulatory role of lipophagy in central nervous system diseases.
https://t.co/Yx3VRdYQOn

[Autophagy Articles @AutophagyJC]

Class 3 PI3K coactivates the circadian clock to promote rhythmic de novo purine synthesis.
https://t.co/SZO7us1wj5

[Autophagy Articles @AutophagyJC]

Tracking the Transition from an ATG9A Vesicle to an Autophagosome.
https://t.co/FCtT9ytCJH

[Autophagy Articles @AutophagyJC]

A mitochondrial SCF-FBXL4 ubiquitin E3 ligase complex degrades BNIP3 and NIX to restrain mitophagy and prevent mitochondrial disease.
https://t.co/S1v8T1kNj7

[Autophagy Articles @AutophagyJC]

ULK phosphorylation of STX17 controls autophagosome maturation via FLNA.
https://t.co/cC1dkMS63X

[Autophagy Articles @AutophagyJC]

LGG-1/GABARAP lipidation is not required for autophagy and development in Caenorhabditis elegans.
https://t.co/FdT3M7nujQ

[Autophagy Articles @AutophagyJC]

Loss of the batten disease protein CLN3 leads to mis-trafficking of M6PR and defective autophagic-lysosomal reformation.
https://t.co/2OH6eTryNU

[Autophagy Articles @AutophagyJC]

A conserved STRIPAK complex is required for autophagy in muscle tissue.
https://t.co/eBRIoqJp5o

[Autophagy Articles @AutophagyJC]

Microglial cytokines poison neuronal autophagy via CCR5, a druggable target.
https://t.co/sYTCNivDUK

[Autophagy Articles @AutophagyJC]

The yeast transcription factor Stb5 acts as a negative regulator of autophagy by modulating cellular metabolism.
https://t.co/N5lOQuNoSN

[Autophagy Articles @AutophagyJC]

The ER calcium channel Csg2 integrates sphingolipid metabolism with autophagy.
https://t.co/fyH7UBrYXZ

[Autophagy Articles @AutophagyJC]

Unique amphipathic α helix drives membrane insertion and enzymatic activity of ATG3.
https://t.co/c8qzEkL9eO

[Autophagy Articles @AutophagyJC]

PARK15/FBXO7 is dispensable for PINK1/Parkin mitophagy in iNeurons and HeLa cell systems.
https://t.co/ydZpK4nQ6w

[Autophagy Articles @AutophagyJC]

Measurement of SQSTM1 by flow cytometry.
https://t.co/gJI8Ayjuha

[Autophagy Articles @AutophagyJC]

PtdIns4p exchange at endoplasmic reticulum-autolysosome contacts is essential for autophagy and neuronal homeostasis.
https://t.co/30oBFsqiDC

[Autophagy Articles @AutophagyJC]

Autophagosome membrane expansion is mediated by the N-terminus and cis-membrane association of human ATG8s.
https://t.co/iOKDAbAxRt

[Autophagy Articles @AutophagyJC]

Assays of Monitoring and Measuring Autophagic Flux for iPSC-Derived Human Neurons and Other Brain Cell Types.
https://t.co/vaO4sPWWZL