BEHcl

Respiratory Viruses Weekly Bulletin (Hospices Civils de Lyon)
VRS study group in Lyon
MD-PhD jean-sebastien Casalegno

[BEHcl @BEHcl]

Flu activity (red) is going down in Lyon (France). RSV (orange) epidemic is almost over. Lets see SARS-Cov-2 (green) next move before we can finally say: "season's over".

[BEHcl @BEHcl]

Rhinovirus causes significant number of infant hospital admissions https://t.co/j767df3ykC

[BEHcl @BEHcl]

Here is our last paper. Rhinovirus is a significant contributor to bed occupancy in the pediatric hospital. An issue that we will need to deal with in the future.
Contribution of Infant Rhinovirus Bronchiolitis to Hospital Bed and Ventilation Use https://t.co/XeVpL4HGUE

[BEHcl @BEHcl]

Influenza (red) and SARS-Cov-2 (green) are tested alltogether (PCR duplex/multiplex) since early 2023. In 2023 most often there was more hospital lab-confirmed SARS-Cov-2 cases detected per week than Influenza. It is changing early 2024 due to the Flu epidemic. Wait and see.

[BEHcl @BEHcl]

RSV (Orange) and SARS-Cov-2 (Green) activity peaked the very same week (W50). Flu (Red) activity is already high. Our population (Lyon) is experiencing three major viral epidemics in a very short time frame at a very special time (christmas). Hope it is not the new seasonality...

[BEHcl @BEHcl]

RSV is slowly coming back to the pre-covid-19 dynamic in Lyon. Still we may not be there yet. It looks like the RSV pic will be earlier this season.

[John Paget, PhD @PagetPhd]

There's a new surveillance Bulletin in town!

And its called the 'European Respiratory Virus Surveillance Summary (ERVISS)'

The ERVISS Bulletin covers influenza, RSV and SARS-CoV-2

Congratulations to all involved

➡️ https://t.co/yD9vOzyoxQ

[BEHcl @BEHcl]

In Lyon (France) the current RSV case detection curve is really close to the mean pre-covid RSV season. Is RSV finally back on track after three atypical post-covid RSV seasons ?

[John Paget, PhD @PagetPhd]

Decreasing SARS-CoV-2 activity in Lyon, France

➡️ Peak week 39/2023 (decrease in number of cases and % positive)
➡️ Adults were mainily affected during this epidemic (those aged 18+ years)

@BEHcl

[BEHcl @BEHcl]

A bit early in the season to take any conclusion. But so far, RSV dynamic mirror the pre-covid-19 RSV dynamic. Maybe RSV is finaly back on tracks ? Wait and see...

[John Paget, PhD @PagetPhd]

SARS-CoV-2 activity continues to increase in Lyon, France (in all ages) - see green line @BEHcl

Season: 23-24- #4 (25 September 2023)

[BEHcl @BEHcl]

https://t.co/uexZfp17Vf
Great paper from Pendrey et al. The influenza picture is getting clearer. International travellers played an important role in introducing new influenza viruses while adolescent and young adults contribute to early community spread.

[BEHcl @BEHcl]

Week 36: looks like we are heading toward scenario 2

[BEHcl @BEHcl]

Week 34 this is where we stand just before school opens. Two plausible scenarios:
1) 2021 actual SARS-Cov-2 wave will end soon while rhinovirus and RSV epidemics will start
2) 2022 SARS-Cov-2 cases will soon rise with increase circulation in school age-children

[BEHcl @BEHcl]

Same trend in Lyon (France). We observe an increase in SARS-Cov-2 positive rate for all groups since three weeks. Fascinating how it can be so synchronise across countries. Hope it is not an august covid wave.
US COVID markers continue slow summer rise https://t.co/qhi7J1jCkc

[BEHcl @BEHcl]

@clotilde_egs RED around 50% positive rate (maximum observed); YELLOW 1 to 10 %. Hard to see but PCR positive rate values are indicated in the table. On average in summer we detected 1 to 2 new influenza adult cases every week. Some patients have a recent history of travel but other's don't.

[BEHcl @BEHcl]

Now we are testing for Influenza year-around we can pick-up some flu activity during summer (mostly in adults). See heat map of PCR positive rates per week and age groups in Lyon (2022-2023). Low endemic circulation ? Multiple introductions from abroad ?

[John Paget, PhD @PagetPhd]

There are currently low levels of respiratory viruses activity in Lyon, France

➡️Influenza, RSV, SARS-CoV-2, Metapneumovirus and Picornaviruses (Rhinovirus and Enterovirus) - see Figure
➡️@BEHcl

[John Paget, PhD @PagetPhd]

Influenza activity in the Southern Hemishphere

▶️Two countries where activity is currently increasing
▶️Australia (left) and Colombia (right)

[John Paget, PhD @PagetPhd]

Interesting to see the seasonality of SARS-CoV-2 in Lyon France in 2021, 2022 and 2023

➡️ There appears to be a pretty clear March-April seasonal wave #COVID19
➡️Summer seasonality is less clear
➡️ Source: Bulletin Epidémiologique Hebdomadaire, Hospices Civils de Lyon @BEHcl