Congratulations to all our team members. Our new paper was just published at Cell Reports Medicine: A synergistic two-drug therapy specifically targets a DNA repair dysregulation that occurs in p53-deficient colorectal and pancreatic cancers: Cell Reports Medicine
Love to see great basic science moving into the clinic. Congrats to Dr. Christos Fountzilas @RoswellPark on his @NCCN YI award on novel combination therapy for colorectal/esophagogastric cancers. This work builds on @GeneticsRoswell expert Dr.Andrei Bakinโs work on p53 and BER.
@CommsBio just published a paper exploring a new therapeutic approach targeting p53 mutant cancer using a combination of fluorinated deoxyuridines and PARP1 inhibitors https://t.co/dTqeJ8kfme.