Carlo Alberto Barcella

MD, PhD - Department of cardiology at Herlev-Gentofte University Hospital

[Carlo Alberto Barcella @BarcellaCarlo]

@argulian Dissection

[Carlo Alberto Barcella @BarcellaCarlo]

@argulian MVP with late systolic MR

[Carlo Alberto Barcella @BarcellaCarlo]

@argulian I find often difficult to identify the real e' when the patient has Afib since there are often several negative waves. For example which wave would you pick in the pictures? The patient has LVH and for sure diastolic dysfunction but quite high e'.

[Carlo Alberto Barcella @BarcellaCarlo]

@argulian So? What was the answer?

[Ritika Tuli @RitikaTuliMD]

CardioNugget™ 🫀

Why does diastolic MR occur in acute severe Aortic Regurgitation?

1️⃣ Acute severe AR → rapid filling of a noncompliant LV
2️⃣ LVEDP rises dramatically
3️⃣ LV diastolic pressure exceeds LA pressure → premature mitral valve closure
4️⃣ LV pressure continues to rise in late diastole → blood is forced back across the closed mitral valve = diastolic MR

Often accompanied by premature MV closure and a normal-sized LV in acute severe AR.

#CardioNugget™ #EchoBoards #EchoFirst #ASEcho #Cardiology #FOAMed #BoardPrep #AorticRegurgitation

[Carlo Alberto Barcella @BarcellaCarlo]

@TheECGMedic Slow coarse Atrial fibrillation

[Carlo Alberto Barcella @BarcellaCarlo]

@DrRajeshG1 EAT

[Carlo Alberto Barcella @BarcellaCarlo]

@IhabFathiSulima Amyloidosis

[Carlo Alberto Barcella @BarcellaCarlo]

@healthefyheart @nihar_nayak2 @docakx @DrAatish_ @DrRajeshG1 @AlainaZameer @Drakhil_cardio Restrictive PML?

[Carlo Alberto Barcella @BarcellaCarlo]

@TrackYourHeart C

[HeartRhythm @hrs_journal]

Long-term outcomes among patients with and without psychiatric disorders following Out-of-Hospital Cardiac Arrest

@BarcellaCarlo @fordycecb

https://t.co/up6PVlJApX

[Carlo Alberto Barcella @BarcellaCarlo]

@sarahhudsonuk @leylaelifsade @DanXAugustine @MilicicaStefano @shaunrobinson02 @leilii I cannot watch the video. Is it still available?

[Carlo Alberto Barcella @BarcellaCarlo]

@TrackYourHeart @saide_aytekin C

[Carlo Alberto Barcella @BarcellaCarlo]

@NMerke Regurgitation volume falls in the severe range, but fraction in moderate. E is "only" 1,1 m/s. There could be other reasons for LV and LA dilation. What's the degree of severity?

[Carlo Alberto Barcella @BarcellaCarlo]

@argulian Complete heart block?

[EHJ-IMP Editor-in-Chief @EHJIMPEiC]

📄 Sex differences in moderate aortic stenosis: new longitudinal insights

🔗 https://t.co/ZuPlMei8wf

🫀 A longitudinal study of >500 patients with moderate aortic stenosis highlights important sex-specific differences in left ventricular remodeling.

✨ Key findings:
🔹 Women develop concentric hypertrophy and diastolic dysfunction at lower transvalvular gradients
🔹 They exhibit more pronounced diastolic dysfunction throughout follow-up
🔹 Dyspnoea is more common at presentation
🔹 Despite this, no differences in outcomes were observed:
➡️ symptom onset timing
➡️ aortic valve replacement
➡️ mortality

📊 These findings suggest greater sensitivity of the female myocardium to pressure overload, even at earlier stages of disease

💡 Clinical take-home message:
👉 Sex-specific differences emerge early (moderate AS stage)

👉 This may support:
closer surveillance in women
more tailored management strategies
rethinking timing of intervention

🚺 Aortic stenosis is not the same disease in women and men:
the pathophysiology differs—even when outcomes appear similar.

#Cardiology #AorticStenosis #Echocardiography #SexDifferences #WomenInCardiology #HeartValveDisease #CardiacRemodeling #HFpEF #TAVR #PrecisionMedicine 🫀📊

[Carlo Alberto Barcella @BarcellaCarlo]

@DrRajeshG1 Very likely VT (fusion beats, RS interval > 100ms)

[Carlo Alberto Barcella @BarcellaCarlo]

@VLSorrellImages @echogenics @CASEfromASE @ASE360 Probably A

[Carlo Alberto Barcella @BarcellaCarlo]

@sudarshanballa @WvuCvFellows @harshi_md @BritoCardio @CASivaram1 @argulian @alex1708ander Splay sign!

[Carlo Alberto Barcella @BarcellaCarlo]

@DisrespectedThe He will die anyway of an overdose within a few months