Becca Cole

Neuroscience PhD student in the Joffe lab @ the University of Pittsburgh | interneurons, opioids, and PFC | Boston U ‘22 | she/her

[Becca Cole @Beccaaa_57]

Our paper on opioid receptor regulation of mPFC inhibitory microcircuits is out as an early release https://t.co/ntJe0dNTrv @allichonmc @mejoffe ! More to come on these systems in opioid dependence 🧠

[Luca Posa @DrLu_Po]

Excited this paper is out @CellCellPress ! 🎉
This work explores the role of MOR and SST interneurons in ketamine’s antidepressant effect and identifies synergistic approaches to develop new therapeutics. Big shoutout to @hermanymv and all the team!

https://t.co/p0VAqgMxVR

[Max Joffe @mejoffe]

We focused on L2/3 PL. Certainly there is more MOR in pyramidal cells in deeper and caudal regions of cortex. We could have a substantive discussion about the biology but instead you're out here subtweeting trainees and dragging their science. This behavior is weird and mean

[Marie-Charlotte @allichonmc]

🚨 New review out! We summarize how MOR and NOPR exert divergent , cell-type-specific control over VTA-NAc-PFC circuits in opioid use disorder https://t.co/yZdtAAH144

[Hugo Tejeda @NeuroTejeda]

Happy to share the latest preprint from the lab. Work examining the role of somatostatin neuropeptide transmission in the PFC in regulating associative learning underlying discrimination between salient and neutral outcomes. Led by @Miigii13

https://t.co/n1jniU2EYg

[Becca Cole @Beccaaa_57]

Incredibly grateful for my @NIDAnews F31 to study DOR signaling in oxycodone dependence and withdrawal

[Max Joffe @mejoffe]

NGA for @Beccaaa_57 F31 arrived today! Very glad to see her work and potential recognized with support from @NIDAnews

[Malaika @Maliqa_M]

So honored to have been 1 of the 50 recipients of this grant, which was instrumental in launching my career!

In uncertain times, it’s reassuring to see Hello Bio stay committed to investing in and supporting the future.

Grateful to be featured in this article—give it a read ⬇️

[Max Joffe @mejoffe]

Excited to present some of @Beccaaa_57's work on opioid receptor regulation of PFC transmission today! Very thorough characterization and some neat findings in a model of opioid dependence. Come find me at M217. @ACNPorg #ACNP2024

[Becca Cole @Beccaaa_57]

made it out of the lab to see @KamalaHarris !!! 👑 💙 #pittsburghforharris

[Becca Cole @Beccaaa_57]

DOR’s biggest fan

[Max Joffe @mejoffe]

Congrats to @Beccaaa_57 for earning an amazing score on her F31!! So proud of the work she’s put into this project and excited to see where it will go

[Max Joffe @mejoffe]

Our lab is hiring at all levels. Currently have postings up for entry level, more senior, and postdoc positions. Please reach out if interested!

https://t.co/IYXSXwSTSj

https://t.co/jd5e34IIyO

https://t.co/2rmmFKqqCl

[Carly Fabian @carlyfabian231]

Honored to have been selected as a finalist for the Stephen L. Phillips “Best Peer-Reviewed Publication” Award 🎉 Big thanks again to @mejoffe and @SeneyMarianne 😊and for @FarrisSP for coming to support! @NeuroatPitt

[bioRxiv Neuroscience @biorxiv_neursci]

Mu and Delta Opioid Receptors Modulate Inhibition within the Prefrontal Cortex through Dissociable Cellular and Molecular Mechanisms https://t.co/0KP7wGi8di #biorxiv_neursci

[Becca Cole @Beccaaa_57]

@Maliqa_M 🫶🫶🫶

[Max Joffe @mejoffe]

Presynaptic and somato-dendritic DOR functions are greatest in SST cells, while MOR's effects and putative subcellular location vary extensively across cell types. Lots of neat data in this one, including a new tool made by @FlyBottleEscape and @gsalimando to target MOR+ cells

[Max Joffe @mejoffe]

Excited to share our first foray into opioid research! @Beccaaa_57 set out to build a comprehensive picture of opioid receptor function within PFC interneurons. Becca characterized several pronounced and contrasting effects across the major GABAergic cell types and circuits...

[Becca Cole @Beccaaa_57]

there is no escape

[Becca Cole @Beccaaa_57]

so much fun + such cool science at my first Addiction GRS/GRC !!🦞🧠🥹

[Becca Cole @Beccaaa_57]

365 party girl

[Carly Fabian @carlyfabian231]

Honored to have received the official Notice of Award for my F31 NRSA application the other day! 🎉 Huge thanks to @NIAAAnews for supporting my work and all those who helped me through this process @mejoffe @mtorregrossa1 😊