Bioequivalence & Bioavailability

Journal of Bioequivalence & Bioavailability is a peer reviewed, open access journal dedicated to publishing research on all aspects of Drug Therapeutics.

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NRTIs are taken as prodrugs and must be taken into the host cell and phosphorylated before they become active. Once inside the host cell, cellular kinases will activate the #drug.

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The nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs) were the first class of antiretroviral #drugs to be approved by the #FDA.

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Drugs often have several names. When a drug is first discovered, it is given a chemical name, which describes the atomic or molecular structure of the drug. The chemical name is usually too complex and cumbersome for general use.

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Chemical #drugs have a low molecular weight and derive from a production process based on chemical synthesis starting from compounds which, under defined conditions, give rise to pharmacologically active molecules.

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In some cases – often in the #treatment of #disease such as #Cancer, #HIV infection and diabetes – multiple #drugs with different active ingredients may be administered, which is known as combination #therapy.

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Drug therapy (or pharmacotherapy) involves the administration of #drugs to treat or prevent #disease.

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Anti-infectives is a general term used to describe any medicine that is capable of inhibiting the spread of an infectious organism or by killing the infectious organism outright.

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Anti-infectives are medicines that work to prevent or treat infections, they include antibacterials, antivirals, antifungals and antiparasitic medications.

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Omeprazole is in a class of medications called proton-pump inhibitors. It works by decreasing the amount of acid made in the #stomach.

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#pharmacology has been identified as a critical undergraduate degree required to develop new medicines, improve current therapies and to treat #patients.

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Antimicrobial resistance happens when germs like bacteria and #fungi develop the ability to defeat the drugs designed to kill them.

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#drug resistance may be present before treatment is given or may occur during or after treatment with the drug.

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metformin is used to lower blood sugar levels in diabetes. Metformin is the generic form of a drug which is also available under the brand name Glucophage.

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the U.S. Food and Drug Administration approved Xenpozyme (Olipudase alfa) for intravenous infusion in pediatric and adult patients with Acid Sphingomyelinase Deficiency (ASMD), a rare genetic disease that causes premature #Death.

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Tablets may contain one or more of functional ingredients such as diluents (also known as fillers), binders, disintegrants, glidants, lubri-cants, coating materials, coloring agents, stabilizer(s), sweeteners, and fla-voring agents.

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A tablet formulation typically comprises one or more active substance(s) and other excipients that are required to enable the pharmacokinetic and mechanical properties of the final dosage form.

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#drug evidence may be in the form of plant material (such as marijuana, synthetic cannabinoids, salvia, and khat).

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The primary goal of the #forensics #drug examiner is the unequivocal identification of any controlled substance present in a drug exhibit.

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The most common omeprazole side effect is #headache. But it can also cause stomach-related side effects, such as nausea, vomiting, or diarrhea.

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Most #drugs undergo chemical alteration by various bodily systems to create compounds that are more easily excreted from the #body.