💯🧬 Jake 🧬💯

👽 🪦 🧟 👽

💯 Club 💯

[💯🧬 Jake 🧬💯 @Biohacker_Jake]

Feeling overall good and hit 224lbs this am!

Don’t miss a day!

Fire at will 🔥

[💯🧬 Jake 🧬💯 @Biohacker_Jake]

If only I was as successful with appeals as I was with that shot 😂 🔥

[Peptide Central @peppycentral]

You’re looking at @Biohacker_Jake trying to get off X suspension for the thousand time.

[💯🧬 Jake 🧬💯 @Biohacker_Jake]

@Azlatin1313 Gotta make it look epic for the picture 😂

[💯🧬 Jake 🧬💯 @Biohacker_Jake]

Moaarrr chicken 🍗

[💯🧬 Jake 🧬💯 @Biohacker_Jake]

Immediately the first response that comes to mind with this is are people supposed to not use new technology to make daily activity/jobs etc easier?

Just because something applies to health it gets looped into the “natural” lifestyle defense and draws criticism, im saying this to hedge the rebuttal point of “well using AI or computers isn’t the same as putting something in your body”.

Anyone can point a finger and make a argument against the type of people who take things that serve primarily a medical purpose to someone who may have an issue, and dosing too high or just flat out using a compound that isn’t for them in ANY way, but to say you can’t benefit from something that that has a plethora of benefits (even if it’s a preventative reason) in reasonable doses is pretty fucking asinine.

[💯🧬 Jake 🧬💯 @Biohacker_Jake]

Maybe this is the one?

[💯🧬 Jake 🧬💯 @Biohacker_Jake]

@mannyjplays I still have no idea what is going on with this entire trend of every nation warning this now lol

[The Reconstitutionalist @WeThePeptides]

Eli Lilly Sends Armed Lawyers To Antarctica To Shut Down Florida Man Brewing Retatrutide In His Igloo https://t.co/WPZJ33kxXw @pepfessions @troywhiteyyc @JayCampbell333

[Yahoo Fantasy Sports @YahooFantasy]

The Eagles not giving Saquon an injury designation as he limps off the field after every run

[💯🧬 Jake 🧬💯 @Biohacker_Jake]

A masterclass on Vilon.

https://t.co/f1Q7Ez2Xc5

[💯🧬 Jake 🧬💯 @Biohacker_Jake]

@Scott21217154 Probably just shouldn’t eat in the middle of the night my dude!!

[💯🧬 Jake 🧬💯 @Biohacker_Jake]

For further context, I’m not flat out saying you can’t morning dose, but as I commented once below, it appears a lot of GHRH logic bled into HGH logic on YouTube, Reddit, X, etc when it’s completely different and timing is WAY less important for the food intake, as long as your not eating awhile after (strictly for the small edge of lipolysis HGH offers) alongside its plethora of other benefits.

Again, a small fake edge is the pointed out argument here, not an overall you can’t do this*

[💯🧬 Jake 🧬💯 @Biohacker_Jake]

HGH belongs at night

This is supposed to be controversial. It’s supposed to draw attention. But it’s true if we’re talking about what’s more optimal, and what makes the most sense, for someone who wants to run it long-term.

I didn’t say convenient.

Someone taking it in the morning because they can’t sleep on it is choosing convenience with a side of “this works for me.” That can still be the right call for them. It just isn’t the most optimal use of the compound.

Your biggest natural GH pulse happens at night, tied to the first deep slow-wave sleep. In men, a large portion of daily output (often the majority) occurs early in sleep. That’s why protocols for GHRH analogs like CJC are commonly started at night when possible. The short pulse is less “punishing” long-term than exogenous GH, but the night preference is still there because it lines up with how the body is already set up, and because dosing some of them in the morning can mess with energy in ways people notice.

With actual HGH you’re replacing. You’re completing the picture if you’re already on the other hormones. You’re not just poking a secretagogue and hoping for a pulse; you’re putting the hormone in yourself. Nighttime keeps that closer to how the body is wired to use it.

A lot of videos and write-ups push morning dosing as “better for fat loss.” It has zero real advantage over nighttime for that. Literally zero beyond convenience if you can’t tolerate it at night. There is no magic extra fat burn from pinning when you wake up.

GH doesn’t go to work the second the needle comes out. After a subcutaneous shot, levels typically peak in the 3-6 hour range (often around 4-5 hours depending on site and individual). That’s when lipolysis is ramping hard, free fatty acids rise after the first couple of hours and stay elevated for a good window after. So even if you ate something reasonably close to a nighttime dose, by the time the peak and the strong lipolytic window hit, your insulin is usually in a much better place. You’re fasted for hours while the strongest effect is playing out. You wake up with fatty acids already mobilized.

Morning dosing flips that. People say “you’re already fasted when you wake up, so just pin and wait an hour.” But the peak and the strongest lipolysis aren’t happening in that first hour. They’re happening later, right as most people are eating breakfast and lunch. GH raises insulin resistance to a degree; it is counter-regulatory. Do you want that resistance peaking and playing out across your daytime meals, or largely while you’re sleeping and fasted? Just because you’re fasted at injection time doesn’t mean the work is done immediately. You’re more likely to be dealing with the insulin-resistance side of GH through the part of the day when you’re actually eating.

It’s not the end of the world, you still get GH in you, but it is not superior for fat loss, and over time it is the less clean setup unless you stay strictly fasted for 5-8 hours after the morning shot. Most people are not doing that.

Data on this lines up with the physiology. Evening dosing has been shown to produce higher peak GH levels, hold IGF-1 more steadily, and avoid the higher daytime insulin seen with morning dosing. Morning dosing has also been linked to higher markers of protein breakdown overnight. Total daily dose still matters more than the clock for body composition, but the single night dose is the cleaner physiological choice for most people.

For the “set it and forget it/I want to run this forever and monitor it” approach, nighttime is the move. It matches the natural rhythm, manages the insulin side better for daily life, and keeps the lipolytic window in the long overnight fast.

Different use cases exist, with higher performance doses where people split to avoid dumping too much at once (above roughly 5-6 IU for some), or pure IGF-1 chasing when stacked with TRT/AAS. Those are different goals.

For longevity-range or steady use, night is the straightforward answer.

If sleep is an issue, try to power through it for a stretch and let your body adjust if you can. It’s still the optimal window. Convenience is fine when you need it. Optimal is night.

[💯🧬 Jake 🧬💯 @Biohacker_Jake]

@ElevateBiohack 💪 😂

[💯🧬 Jake 🧬💯 @Biohacker_Jake]

@whiteboigocrazy @James9thLife Lmao I did see that egg post one floating around lol

[Adam Schefter @AdamSchefter]

Eagles running back Saquon Barkley said his “hamstring came out great” and he doesn't believe his back issue will keep him out.

Story via @Tim_McManus: https://t.co/WtY4RsczJq

[💯🧬 Jake 🧬💯 @Biohacker_Jake]

@ElevateBiohack Only 10% 🫣!!!!

[💯🧬 Jake 🧬💯 @Biohacker_Jake]

I wouldn’t be concerned at all with it being GH versus GHRH.

Its peaking hours later where your insulin is much lower, even despite the reta.

People look at Reta as a negative for GH fasting timeframe when actually it’s quite the opposite, it improves insulin sensitivity so if anything it works great with the main side worry or GH overall.

But I get the idea people think it slows down digestion so much your insulin stays elevated for dramatic amounts of time through.

[💯🧬 Jake 🧬💯 @Biohacker_Jake]

HGH belongs at night

This is supposed to be controversial. It’s supposed to draw attention. But it’s true if we’re talking about what’s more optimal, and what makes the most sense, for someone who wants to run it long-term.

I didn’t say convenient.

Someone taking it in the morning because they can’t sleep on it is choosing convenience with a side of “this works for me.” That can still be the right call for them. It just isn’t the most optimal use of the compound.

Your biggest natural GH pulse happens at night, tied to the first deep slow-wave sleep. In men, a large portion of daily output (often the majority) occurs early in sleep. That’s why protocols for GHRH analogs like CJC are commonly started at night when possible. The short pulse is less “punishing” long-term than exogenous GH, but the night preference is still there because it lines up with how the body is already set up, and because dosing some of them in the morning can mess with energy in ways people notice.

With actual HGH you’re replacing. You’re completing the picture if you’re already on the other hormones. You’re not just poking a secretagogue and hoping for a pulse; you’re putting the hormone in yourself. Nighttime keeps that closer to how the body is wired to use it.

A lot of videos and write-ups push morning dosing as “better for fat loss.” It has zero real advantage over nighttime for that. Literally zero beyond convenience if you can’t tolerate it at night. There is no magic extra fat burn from pinning when you wake up.

GH doesn’t go to work the second the needle comes out. After a subcutaneous shot, levels typically peak in the 3-6 hour range (often around 4-5 hours depending on site and individual). That’s when lipolysis is ramping hard, free fatty acids rise after the first couple of hours and stay elevated for a good window after. So even if you ate something reasonably close to a nighttime dose, by the time the peak and the strong lipolytic window hit, your insulin is usually in a much better place. You’re fasted for hours while the strongest effect is playing out. You wake up with fatty acids already mobilized.

Morning dosing flips that. People say “you’re already fasted when you wake up, so just pin and wait an hour.” But the peak and the strongest lipolysis aren’t happening in that first hour. They’re happening later, right as most people are eating breakfast and lunch. GH raises insulin resistance to a degree; it is counter-regulatory. Do you want that resistance peaking and playing out across your daytime meals, or largely while you’re sleeping and fasted? Just because you’re fasted at injection time doesn’t mean the work is done immediately. You’re more likely to be dealing with the insulin-resistance side of GH through the part of the day when you’re actually eating.

It’s not the end of the world, you still get GH in you, but it is not superior for fat loss, and over time it is the less clean setup unless you stay strictly fasted for 5-8 hours after the morning shot. Most people are not doing that.

Data on this lines up with the physiology. Evening dosing has been shown to produce higher peak GH levels, hold IGF-1 more steadily, and avoid the higher daytime insulin seen with morning dosing. Morning dosing has also been linked to higher markers of protein breakdown overnight. Total daily dose still matters more than the clock for body composition, but the single night dose is the cleaner physiological choice for most people.

For the “set it and forget it/I want to run this forever and monitor it” approach, nighttime is the move. It matches the natural rhythm, manages the insulin side better for daily life, and keeps the lipolytic window in the long overnight fast.

Different use cases exist, with higher performance doses where people split to avoid dumping too much at once (above roughly 5-6 IU for some), or pure IGF-1 chasing when stacked with TRT/AAS. Those are different goals.

For longevity-range or steady use, night is the straightforward answer.

If sleep is an issue, try to power through it for a stretch and let your body adjust if you can. It’s still the optimal window. Convenience is fine when you need it. Optimal is night.

[New York Jets @nyjets]

Omar. Cooper. Jr.

[Mohi @mohithegoat]

Carlos Prates genuinely has the most terrifying record in the UFC right now

[💯🧬 Jake 🧬💯 @Biohacker_Jake]

@johnpaulp I originally did morning dosing.

I actually got really sick for a week and had a timeframe to change up stuff and that was one of em lol

[💯🧬 Jake 🧬💯 @Biohacker_Jake]

@johnpaulp Results will be similar as far as IGF-1 goes, should at least 💪 🤞

[💯🧬 Jake 🧬💯 @Biohacker_Jake]

@biotides Bro good
Fucking work!

[💯🧬 Jake 🧬💯 @Biohacker_Jake]

I really don’t hate it. It’s just there is a weird fad about it’s benefits and it’s not quite there for that fat loss angle solely in the am..

The reason your doing that is to be able
To get more GH daily but mitigate sleeping like shit to get 4ius. That’s similar to what I referred to in the end. Sounds like you respond strong to 4 where
Some need so fucking much, which imo is just high dimer bad quality GH for them lol, but nonetheless