Assassins Creed: Brotherhood set the precedent for what one man's ideas and creations with his team, actually set the mainline RPG Series into play and were heavily inspired on those ideas.
Aya= Amunet = AC Origins
Darius = AC Odyssey
Wei Yu = AC Jade.
Brotherhood and the first saga still echo and linger throughout the ages, because Patrice and his original team, Ex-Ubisoft helped set up those games.
Ezio is still the favourite, and still brought back again, again, and again.