A while ago I read about a guy who successfully treated many cancer patients with a mixture of maple syrup and baking soda. So basically a combination of sugar, salt, and CO2. This works in a ton of different ways but the main ones are probably inhibiting lipolysis and shifting the mitochondria towards efficient glucose oxidation, working towards eliminating or at least lessening the warburg effect (cancer cell metabolism) ..where cells when oxidizing substrate produce as byproducts lactate which is inflammatory, instead of urea and CO2 which are both anti inflammatory.
Also cancer thrives in an acidic environment and thus treatments using baking soda by itself are being studied for cancer treatment as it is a very basic (versus acidic) substance. It’s interesting to note also that since the warburg effect increases lactic acid production, CO2 can also help ameliorate the negative effects of it. Similarly to how the body mixes bicarbonate in the small intestine to render inert the stomach acid. CO2 is also a potent anti inflammatory which can’t hurt.
Then of course you have salt which reduces serotonin and prolactin, and thus estrogen, and also adrenaline which all slow the metabolism and inhibit glucose oxidation.. estrogen also in large enough quantities WILL cause cancer. This is relatively widely known. To the extent that doctors use the same estrogen blockers that bodybuilders use for breast cancer treatment. You also sometimes see warnings on products containing estrogen that say “this product is known to cause cancer in the state of California”
things i’d try before ever considering SSRIs:
bromantane
myo-inositol
testosterone
more caffeine
saffron extract
cerebrolysin cycle
theanine + taurine
daily vitamin d/k/zinc
modafinil/armodafinil
high dose vitamin E + C
fix thyroid/T3 microdosing
BPC-157 cycle for gut-brain reset
fix methylation (TMG + b-complex)
sprint often
read ‘the war of art’
take your own advice
never sleep over 8hrs
no food 2hrs before bed
20 mins of sunlight daily
jump rope every morning
consistent sleep/wake time
morning sunlight/short walk
increase carb & sugar intake
lifting 3x p/w + mobility training
direct procrastination into the halo effect
identify your god-given talent & master it.
There's a subset of people I've met that did best on fairly small doses of thiamine rather than megadoses, think 5-20mg
This could be for a few reasons, impurity in the supplement causing allergy, cross reaction with deficiencies in other vitamins or minerals, etc
Considering that the RDI for B1 is 1.1mg, I don't think this is necessarily a bad starting point
If possible I'd even suggest taking an "allergy test" microdose of any new supplement before you start taking it
From there, if you're getting paradoxical responses to thiamine in low doses, it's best to assess:
- status of related cofactors like B12, B2, B3, selenium, and magnesium
- quality of source
- presence of toxic additives like silicon dioxide, talc, or titanium dioxide
- specific form, TTFD and benfotiamine may cause more side effects than thiamine hcl or TPP (coenzymated B1)
It's okay to start low and experiment over time, you'll still be able to address and prevent a deficiency even with a few milligrams a day
My current regular supplement stack:
- Benfotiamine/Thiamine Hcl
- Magnesium glycinate
- Shilajit
- Vitamin K2
- Collagen
A few times a week I take taurine, bacopa, gingko, and biotin
Caffeine from coffee or tea most days
If you are experiencing brainfog and memory loss due to depression and anhedonia, I would STRONGLY advise that you supplement with vitamin B1.
The best form of vitamin B1 is Thiamine HCl - by far.
Here's science-backed advice for lowering cortisol ASAP:
1. Fix your T3 (TSH under 2)
2. Ruck with 30 lbs for 60 minutes in nature
3. Eat the Big Five (red meat, liver, egg yolks, oysters, milk)
4. Never train fasted
5. Add magnesium, zinc, pregnenolone
6. Sleep deep
7. Resolve stress instead of avoiding it
Not meditation. Not apps. Not supplements. Biology.
Start with fixing circadian rhythm: bright days, dark nights. Download Cronometer app, ensure you’re hitting all micronutrient bases, especially Mg, Ca, Zn, Cu, Fe, Mn, and B vitamins though they’re all important. Find a caloric point where you’re not gaining fat dependent on muscle growth goals. Establish a foundation because it’s rare you have one when you begin to feel like this.
Astragalus, Oat straw, and Rhodiola all in a cup of tea once or twice per day will begin to stabilize the nervous system. Include oral and topical multiform magnesium saturation, literally soak your body down with topical MgCl with focus on back of head and neck. 500-1000mg L-theanine per dose, 3-6g Taurine/day, large spoonful of inositol dissolved under the tongue. Lots of tools available to you. You can search my profile for “GABA” and find tons more. 🙏💗
Sunlight itself contributes to setting natural circadian rhythm, the necessary vitamin D production for calcium metabolism via UVB, positively influences the gut microbiome via UVB (shared study on this recently), as well as having antimicrobial properties in itself.
If you have a so-called "autoimmune" disease, check your prolactin level. If hypothyroidism exists, prolactin will be very difficult to lower.
"Many autoimmune diseases, such as lupus, rheumatoid arthritis, Sjögren’s syndrome, Hashimoto’s thyroiditis, multiple sclerosis, and psoriasis, are suggested to be associated with high prolactin levels and possible hair loss." https://t.co/ogmCMqeuzW