I can't believe @sensible__med retweeted this horrible take. It demonstrates how little appreciation the sensible med crew has for basic biology.
The desmoplastic stroma of PDAC is so dense that no biologic drug can penetrate. PDAC learned to hijack every immune suppression mechanism - CAFs, MDSCs, TAMs, Tregs. Immune checkpoint inhibitors have ZERO effect on PDAC.
This is the perfect example of medical nihilism!
Today's $RVMD study outcome in pancreatic cancer is a good lesson for all the $IBRX @DrPatrick fans.
Stop with all the hand-waving "cancer cure" podcasting social media nonsense. Shut up and run well-designed clinical trials with definitive endpoints. If you have a drug that truly helps patients, the data will speak loudly for you.