Fantastic research group camping outing last weekend: two nights of a northern lights show, a beautiful float and card games. Perfect weather only a few days after an 8” snow storm. @BroderickLabFeS
Check out our #potw! Thanks Alina for presenting this cool work about a radical SAM epimerase by the Broderick lab. Read to learn how a conserved Cys to Ser mutation helped trap and characterize the α-C • intermediate of OspA using rapid quench & EPR
https://t.co/e1zjLMHzPy
Congrats to @AnnaVagstad bringing this amazing story to the finish line! Thank you to everyone involved from @BroderickLabFeS for the fantastic collaboration! If you are interested in the enzymatic mechanism of peptide epimerization by rSAM, make sure to read it.👇
Kudos to grad student Will Walls @BroderickLabFeS on outstanding work that led to his first @J_A_C_S paper! Congrats also to undergrad Tyler Delridge, Will Broderick, and collaborators @AnnaVagstad and @piel_lab. Radical epimerization in RiPP maturation.
We showed that upon reductive SAM cleavage, the 5’-dAdo radical moves *towards* the [4Fe4S] cluster, on its way to forming the omega organometallic intermediate. The once elusive radical, triangulated! @BroderickLabFeS @MartinMosqueraT
New in ChemComm:
@joanbroderick and colleagues report the semisynthetic maturation of [FeFe]-hydrogenase, revealing new insights into the nature of H-cluster biosynthesis.
@BroderickLabFeS
https://t.co/JAhFu4jsQj
A new mini review from our lab focusing on in vitro [FeFe]-hydrogenase maturation. Interesting chemistry & biochemistry with still so much to learn!
Congrats to Katherine on graduating today with a B.S. in Chemistry/Biochemistry. She has been an awesome research student and lab mate and we will miss her!
Dana Longcope of @montanastate has been elected to the National Academy of Sciences for research on the nature of solar magnetism, and magnetic topology. #NAS159
Read more: https://t.co/bMRNU2Hm2R #physics
Congratulations to Joan B. Broderick of @montanastate who joins the National Academy of Sciences for her outstanding contributions to biochemistry. #NAS159
Read more: https://t.co/LJIsdZn9PN #biochemistry
Congratulations to the newly elected members of the American Academy! Today we are honored to welcome 261 exceptional individuals - including artists, scholars, scientists, and leaders in the public, non-profit, and private sectors - into the Academy.
https://t.co/7uJ8ygxxhd
A grad student interested in teaching positions? A post-doc looking to diversify? The @BUChemistry PAL program has been a successful way for training toward a PUI position! We are looking for 3 new PALs. You'll have a research and a teaching mentor! https://t.co/bDbRYW7T2I
[FeFe]-Hydrogenase: Defined Lysate-Free Maturation Reveals a Key Role for Lipoyl-H-Protein in DTMA Ligand Biosynthesis (Broderick) @BroderickLabFeS https://t.co/j7QmihPDym