Membranoproliferative Glomerulonephritis (MPGN).
I classified the disease into Immune complex (IC) MPGN and complement MPGN (now called C3G) back in 2011.
The IC in IC-MPGN come from autoimmune dis, infections or monoclonal gammopathy. Careful and diligent work up will reveal the underlying etiology in >95% of IC-MPGN.
Idiopathic or primary IC-MPGN is very rare in my opinion.
Be careful of entrapment of Ig, these are C3G to begin with.
And some cases of C3G may represent IC-MPGN, particularly in infections or in some cases where IC is minimal or may need unmasking.
In this review, I describe the pitfalls in the diagnosis, practical considerations on biopsy findings of MPGN.
https://t.co/J1IBirZdTN
💧How is fluid restriction failure defined in SIAD?
• ≤3 mEq/L Na rise at day 4
• ≤5 mEq/L at day 7
✅️ NaCl 3.6 g/day + furosemide 40 mg/day → ~1.5 mmol/L/day sodium increase after FR failure.
@CKJsocial
https://t.co/aFAlJHRz3s
🧐NEW pro/con:
👍Hematuria as a biomarker guiding treatment decisions in IgA nephropathy? Yes
🆓https://t.co/dfNCz0hKJ4
👎Hematuria as a biomarker guiding treatment decisions in IgA nephropathy? No
🆓https://t.co/HNKPsFmPrv