Grab ‘n go: siderophore-binding proteins provide pathogens a quick fix to satisfy their hunger for iron!
Read #FirstRxns https://t.co/jsbFLVrlNF by @ADGallo56 & Katherine Franz @FranzLabDuke on the research by the Wencewicz Lab
@WashUChem https://t.co/1ixmwJR8aq
Bragging about huge numbers of hours worked each week misses two important truths:
-time at work doesn’t necessarily equal productivity
-there is no prize for suffering the most
.@UCSB_chemistry’s graduate students recently discovered a technique to decipher siderophore's 3D structure. A better understanding this compound potentially means thwarting bacterial growth and treating certain illnesses. Findings appear in @PNASNews. https://t.co/WisCfVe8WU
"Mentoring: Reflections and Suggestions" -- Don't miss this editorial by Harry Gray, pioneer of #bioinorganic chemistry. Alison is a proud member of Gray Nation!
Working with just his hand and a very hot flame, #UCSB's in-house glassblower Richard Bock shares his expertise on this niche profession. https://t.co/nHxUBGh7Vr
#UCSB colleagues, sign ups are open for the 2019 Out List! Please consider coming out as member of the LGBTQIA community, or even as a supporter. Visibility matters!
@ucsantabarbara@ucsb_rcsgd
https://t.co/Zmel11hHIn
@jwilcoxen @pinenut666@rdavbritt NSF broader impacts. A significant portion of our grant money goes to promoting tweets and buying followers, but the influencer points make it worth it.
When you finish a PhD in chemistry they take you in a special room and tell you that tenure-track professorships aren't real and all professors are just really old postdocs.
I am posting this at great physical risk to myself and my family.
https://t.co/nhmEaMY6K6
When you finish a PhD in chemistry they take you in a special room and tell you that the periodic table isn't real and all matter is just made of the elements earth, air, fire, and water.
I am posting this at great physical risk to myself and my family.
To sum up, we can now predict the residue selectivity and stereospecificity of any siderophore β-hydroxylase. Although mechanistic questions remain, structures can now quickly be predicted just by looking at the gene cluster, or better yet, by using the pHMMs provided. (11/11)
To confirm that we could actually use these trees to predict siderophore structures, Cliff, Jae, and Jean isolated four siderophores and stereochemically characterized the OHAsp residues. Each matched the subtype-based prediction! (10/11)