CAIN

Cognitive Ageing and Impairment Neurosciences Lab, Adelaide University. Led by Prof Tobias Loetscher and Prof Hannah Keage. Views are our own.

[Andrew Zalesky @AndrewZalesky]

Mapping connectomes in disease?

Check out our article on clinical connectomics in @NeuroCellPress

- Tractography behavior in disease
- How to measure connectivity
- How pathology impacts each stage of connectome mapping
- Multiscale connectomics
https://t.co/u4CcFuPjPL

[JAMA Neurology @JAMANeuro]

Aerobic exercise, intensive blood pressure and cholesterol reduction, or both did not show differences in cognitive function improvement over 24 months among older adults with family history of #dementia or subjective #cognitive decline.

https://t.co/nH3dncXeV5

[Alasdair MacLullich @A_MacLullich]

⭐ META-ANALYSIS: Hospital delirium --> devastating long-term outcomes

253 studies, 137,000+ pts:
• 5.4x dementia risk
• 2.8x institutionalisation
• 2.5x mortality
• 1.7x readmission

⚠️ Delirium = a serious acute problem AND a risk warning.

➡️ All pts deserve robust delirium assessment

[Alzheimer's & Dementia Journals @alzdemjournals]

🫀What is the relationship between adult cardiorespiratory fitness (CRF) and dementia risk? 🫀

Newly published research in #DADM demonstrate high CRF is longitudinally associated with a lower risk of late-onset dementia (🧵1/2)

Full Article: https://t.co/Z98Aauishw

[Aitor Uribarri @Auribarri]

#Delirium is not “just confusion”, it is a major prognostic event in CV medicine.
In our State-of-the-Art Review in #EHJ, we synthesize current evidence on mechanisms, prevention, and management across the CV continuum. 🧠🫀
https://t.co/l4VSzuTQDL
@CekajEndrit et al👏👏

[Alex Fornito @AFornito]

🔥🔥Exciting news!!!🔥🔥

The invited speaker schedule for the 2026 Noosa Brain Workshop has been finalised!

Commuter registrations are still available, but close Feb 1.

3 more weeks to get in!!!

Register here:
https://t.co/J37Kv1JoK2

[Brain @Brain1878]

Togo et al. show strong electrophysiological links between the hippocampus and both the anterior and posterior thalamus, along with robust connections between thalamic subregions. https://t.co/cx0isOqkCe; https://t.co/yWIf8Jufjq

[Alex Fornito @AFornito]

Exciting announcement!

Our Institute is calling for applications for a EMCR 2-year fellowship .

Come and join a great team @turnerinstitute!

Details here:
https://t.co/I2QjJuTNbW

[Australian Academy of Science @Science_Academy]

🏆 Nominate now: 2026 PM's Prizes for Science – Australia's most prestigious science awards. 8 prizes spanning STEM innovation, Indigenous knowledge systems & teaching excellence. $50K or $250K + national recognition. Know a deserving scientist or educator? https://t.co/oXiLHHD88D #PMprizes

[Mark Oldham @MarkOldhamMD]

Yet more evidence that haloperidol is not a sedative.

RCT to ⬇️ agitation in palliative care #delirium

1⃣haloperidol
2⃣lorazepam
3⃣halop + loraz
4⃣placebo

Haloperidol monotherapy was not more efficacious than placebo in reducing RASS.

https://t.co/ceA2P4Oj6y

[JAMA Neurology @JAMANeuro]

The VasCog-2-WSO criteria provide updated international guidelines for diagnosing vascular cognitive impairment and #dementia, incorporating recent biomarker advancements. https://t.co/2KLr8NTQgr

[Agustin Ibañez @AgustinMIbanez]

We reassessed the @TheLancet 14 dementia risk factors and added poverty, wealth shocks, income inequality, & HIV. This provides a larger estimation of preventable dementia & exposes gender inequities with larger burdens in women. Out in @eBioMedicine https://t.co/kBb58VbPdO. Great leadership of Cyprian Mostert and congrats all authors: @MomohChi , Andrea Sylvia Winkler, Connor McLaughlin, @HarrisAEyre , @Mohamed03966736, Kirti Ranchod, @DominicTrepel , @vradenburg3 , William Hynes,@FiegsZA , Shehzad Ali, Najat E. L. Mekkaoui, Alan Landay, @dr_bobrow, @levi_muyela, Kelly Atkins, @ChadhaAnt, @r_marongiu, @PaolaBarbato, @sam_nightinga1e, John Joska, Alfred K. Njamnshi, Mie Rizig, @JamesGKahn1, Karen Blackmon, Zul Merali

[Seb Walsh @seb_walsh]

A privilege to represent the population health perspective, alongside Carol Brayne @CamPubHealth , in this new @TheLancet Series on Alzheimer's disease. Expertly led by @GiovanniFrisoni

Alzheimer's disease outlook: controversies and future directions https://t.co/keHNojvBYN

[CAIN @CAIN_Lab]

2025 ⁦@CAIN_Lab⁩ photo! Although needs Tobias photoshopped in, as he’s overseas.

[Imaging Neuroscience @ImagingNeurosci]

New paper in Imaging Neuroscience by Sian Virtue-Griffiths, Nigel C. Rogasch, et al:

Task-related changes in aperiodic activity are related to visual working memory capacity independent of event-related potentials and alpha oscillations

https://t.co/49vv4NUxaZ

[JAMA Neurology @JAMANeuro]

The VasCog-2-WSO criteria provide updated international guidelines for diagnosing vascular cognitive impairment and #dementia, incorporating recent biomarker advancements. https://t.co/X0D2xZ8Zx8

[Nat Rev Neurology @NatRevNeurol]

Revised Diagnostic Criteria for Vascular Cognitive Impairment and Dementia https://t.co/t7fkQG0tWP

[Victoria Ramos @vicktoriavic]

Prehabilitation Program for Older Adults Undergoing Major Elective Surgery:
Individualized physical therapy, nutritional counseling with protein supplementation, and guided meditation for 3–4 weeks before major surgery

https://t.co/Q2TUmkRL4Z

[Seb Walsh @seb_walsh]

Out of 800+ studies on blood-based biomarkers for Alzheimer's, not a single one measured actual changes in patient outcomes.

https://t.co/u8FMgNDVTV

[CAIN @CAIN_Lab]

Team Leader: Technical Services position now open!

Come work with us on EEG, PSG and VR research studies. The role will support psychology researchers at the new Adelaide University 🧠

https://t.co/x5XAuMOV0l